Macrophage Migration Inhibitory Factor: A Novel Inhibitor of Apoptosis Signal-Regulating Kinase 1–p38–Xanthine Oxidoreductase–Dependent Cigarette Smoke–Induced Apoptosis - Fallica, Jonathan; Varela, Lidenys; Johnston, Laura; Kim, Bo; Serebreni, Leonid; Wang, Lan; Damarla, Mahendra; Kolb, Todd M.; Hassoun, Paul M.; Damico, Rachel (American journal of respiratory cell and molecular biology, 2016)
Keywords: Animals; Apoptosis; Cells, Cultured; Chronic obstructive pulmonary disease; Cytotoxicity; Deoxyribonucleic acid; DNA; Emphysema; Enzyme Activation; Enzymes; Human subjects; Humans; Kinases; Lungs; Macrophage Migration-Inhibitory Factors - genetics; Macrophage Migration-Inhibitory Factors - physiology; MAP Kinase Kinase Kinase 5 - metabolism; Mice; Mice, Inbred C57BL; Nicotiana; Original Research; Oxidative stress; p38 Mitogen-Activated Protein Kinases - metabolism; Phosphorylation; Proteins; Rats; Reactive Oxygen Species - metabolism; Rodents; Smoke; Xanthine Dehydrogenase - metabolism; apoptosis; cigarette; migration inhibitory factor; apoptosis signal–regulating kinase 1; xanthine oxidase