Association of the ACE, GSTM1, IL-6, NOS3, and CYP1A1 polymorphisms with susceptibility of mycoplasma pneumoniae pneumonia in Chinese children

• Published in: Medicine (Baltimore) Vol. 96; no. 15; p. e6642
• Main Authors: Zhao, Jie, Zhang, Wen, Shen, Li, Yang, Xiaomeng, Liu, Yi, Gai, Zhongtao
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer Health 01.04.2017
• Subjects: Alleles; Asian Continental Ancestry Group - genetics; Case-Control Studies; Child; Child, Preschool; China; Cytochrome P-450 CYP1A1 - genetics; Female; Gene Frequency; Genetic Predisposition to Disease; Glutathione Transferase - genetics; Humans; Interleukin-6 - genetics; Male; Mycoplasma pneumoniae; Nitric Oxide Synthase Type III - genetics; Observational Study; Peptidyl-Dipeptidase A - genetics; Pneumonia, Mycoplasma - genetics; Pneumonia, Mycoplasma - microbiology; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors

Mycoplasma pneumoniae is a common cause of community-acquired pneumonia (CAP) and the clinical presentation of mycoplasma pneumoniae pneumonia (MPP) varies widely. Genetic variability affecting the host response may also influence the susceptibility to MPP. Several studies have investigated the asso...