Drosophila Models Rediscovered with Super-Resolution Microscopy

• Published in: Cells (Basel, Switzerland) Vol. 10; no. 8; p. 1924
• Main Authors: Szikora, Szilárd, Görög, Péter, Kozma, Csaba, Mihály, József
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.07.2021; MDPI
• Subjects: Animals; Centrosome - metabolism; Centrosome - ultrastructure; Centrosomes; Drosophila; Drosophila - metabolism; Drosophila - ultrastructure; Electrophysiology; Insects; Labeling; Lasers; Light; Microscopes; Microscopy; Microscopy, Fluorescence - methods; Models, Biological; nanoscopy; Review; Sarcomeres; Sarcomeres - metabolism; Sarcomeres - ultrastructure; SIM; Single Molecule Imaging - methods; SMLM; STED; super-resolution microscopy; nanoscopy; Drosophila; SIM; STED; active zone; centrosome; SMLM; sarcomere; super-resolution microscopy

With the advent of super-resolution microscopy, we gained a powerful toolbox to bridge the gap between the cellular- and molecular-level analysis of living organisms. Although nanoscopy is broadly applicable, classical model organisms, such as fruit flies, worms and mice, remained the leading subjec...