Distribution Characteristics of Air-Bone Gaps: Evidence of Bias in Manual Audiometry

Five databases were mined to examine distributions of air-bone gaps obtained by automated and manual audiometry. Differences in distribution characteristics were examined for evidence of influences unrelated to the audibility of test signals. The databases provided air- and bone-conduction threshold...

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Published inEar and hearing Vol. 37; no. 2; p. 177
Main Authors Margolis, Robert H, Wilson, Richard H, Popelka, Gerald R, Eikelboom, Robert H, Swanepoel, De Wet, Saly, George L
Format Journal Article
LanguageEnglish
Published United States 01.03.2016
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Abstract Five databases were mined to examine distributions of air-bone gaps obtained by automated and manual audiometry. Differences in distribution characteristics were examined for evidence of influences unrelated to the audibility of test signals. The databases provided air- and bone-conduction thresholds that permitted examination of air-bone gap distributions that were free of ceiling and floor effects. Cases with conductive hearing loss were eliminated based on air-bone gaps, tympanometry, and otoscopy, when available. The analysis is based on 2,378,921 threshold determinations from 721,831 subjects from five databases. Automated audiometry produced air-bone gaps that were normally distributed suggesting that air- and bone-conduction thresholds are normally distributed. Manual audiometry produced air-bone gaps that were not normally distributed and show evidence of biasing effects of assumptions of expected results. In one database, the form of the distributions showed evidence of inclusion of conductive hearing losses. Thresholds obtained by manual audiometry show tester bias effects from assumptions of the patient's hearing loss characteristics. Tester bias artificially reduces the variance of bone-conduction thresholds and the resulting air-bone gaps. Because the automated method is free of bias from assumptions of expected results, these distributions are hypothesized to reflect the true variability of air- and bone-conduction thresholds and the resulting air-bone gaps.
AbstractList Five databases were mined to examine distributions of air-bone gaps obtained by automated and manual audiometry. Differences in distribution characteristics were examined for evidence of influences unrelated to the audibility of test signals. The databases provided air- and bone-conduction thresholds that permitted examination of air-bone gap distributions that were free of ceiling and floor effects. Cases with conductive hearing loss were eliminated based on air-bone gaps, tympanometry, and otoscopy, when available. The analysis is based on 2,378,921 threshold determinations from 721,831 subjects from five databases. Automated audiometry produced air-bone gaps that were normally distributed suggesting that air- and bone-conduction thresholds are normally distributed. Manual audiometry produced air-bone gaps that were not normally distributed and show evidence of biasing effects of assumptions of expected results. In one database, the form of the distributions showed evidence of inclusion of conductive hearing losses. Thresholds obtained by manual audiometry show tester bias effects from assumptions of the patient's hearing loss characteristics. Tester bias artificially reduces the variance of bone-conduction thresholds and the resulting air-bone gaps. Because the automated method is free of bias from assumptions of expected results, these distributions are hypothesized to reflect the true variability of air- and bone-conduction thresholds and the resulting air-bone gaps.
Author Margolis, Robert H
Eikelboom, Robert H
Popelka, Gerald R
Saly, George L
Wilson, Richard H
Swanepoel, De Wet
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References 23516088 - J Rehabil Res Dev. 2013;50(1):111-32
6082350 - J Speech Hear Res. 1967 Jun;10(2):232-49
17727085 - Ann Otol Rhinol Laryngol. 2007 Jul;116(7):532-41
19900526 - Hear Res. 2010 May;263(1-2):85-92
15129113 - Otol Neurotol. 2004 May;25(3):323-32
17245035 - Adv Otorhinolaryngol. 2007;65:137-45
23548148 - Int J Audiol. 2013 May;52(5):342-9
18600134 - Ear Hear. 2008 Aug;29(4):524-32
23886428 - J Am Acad Audiol. 2013 Jun;24(6):514-21; quiz 529
24165302 - Ear Hear. 2013 Nov-Dec;34(6):745-52
447779 - J Chronic Dis. 1979;32(1-2):51-63
17252960 - J Am Acad Audiol. 2007 Jan;18(1):78-89
18049964 - Int J Audiol. 2007 Dec;46(12):746-58
20109081 - Int J Audiol. 2010 Mar;49(3):185-94
24099269 - BMC Public Health. 2013;13:936
23713469 - Int J Audiol. 2013 Aug;52(8):526-32
25938502 - Int J Audiol. 2015;54(11):796-805
16534056 - Arch Ophthalmol. 2006 Mar;124(3):363-9
21417674 - Int J Audiol. 2011 Jul;50(7):434-9
15419943 - Arch Otolaryngol. 1950 Jun;51(6):798-808
21668325 - Int J Audiol. 2011 Jul;50(7):440-7
6017931 - J Speech Hear Disord. 1967 Feb;32(1):82-6
24828218 - J Am Acad Audiol. 2014 Feb;25(2):171-86
References_xml – reference: 17252960 - J Am Acad Audiol. 2007 Jan;18(1):78-89
– reference: 21668325 - Int J Audiol. 2011 Jul;50(7):440-7
– reference: 6017931 - J Speech Hear Disord. 1967 Feb;32(1):82-6
– reference: 16534056 - Arch Ophthalmol. 2006 Mar;124(3):363-9
– reference: 18049964 - Int J Audiol. 2007 Dec;46(12):746-58
– reference: 447779 - J Chronic Dis. 1979;32(1-2):51-63
– reference: 19900526 - Hear Res. 2010 May;263(1-2):85-92
– reference: 23548148 - Int J Audiol. 2013 May;52(5):342-9
– reference: 15129113 - Otol Neurotol. 2004 May;25(3):323-32
– reference: 23713469 - Int J Audiol. 2013 Aug;52(8):526-32
– reference: 24099269 - BMC Public Health. 2013;13:936
– reference: 20109081 - Int J Audiol. 2010 Mar;49(3):185-94
– reference: 24165302 - Ear Hear. 2013 Nov-Dec;34(6):745-52
– reference: 17727085 - Ann Otol Rhinol Laryngol. 2007 Jul;116(7):532-41
– reference: 25938502 - Int J Audiol. 2015;54(11):796-805
– reference: 24828218 - J Am Acad Audiol. 2014 Feb;25(2):171-86
– reference: 23516088 - J Rehabil Res Dev. 2013;50(1):111-32
– reference: 17245035 - Adv Otorhinolaryngol. 2007;65:137-45
– reference: 21417674 - Int J Audiol. 2011 Jul;50(7):434-9
– reference: 18600134 - Ear Hear. 2008 Aug;29(4):524-32
– reference: 23886428 - J Am Acad Audiol. 2013 Jun;24(6):514-21; quiz 529
– reference: 15419943 - Arch Otolaryngol. 1950 Jun;51(6):798-808
– reference: 6082350 - J Speech Hear Res. 1967 Jun;10(2):232-49
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Snippet Five databases were mined to examine distributions of air-bone gaps obtained by automated and manual audiometry. Differences in distribution characteristics...
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StartPage 177
SubjectTerms Adult
Aged
Aged, 80 and over
Audiometry, Pure-Tone - methods
Bone Conduction
Databases, Factual
Female
Hearing Loss, Conductive - diagnosis
Hearing Loss, Mixed Conductive-Sensorineural - diagnosis
Hearing Loss, Sensorineural - diagnosis
Humans
Male
Middle Aged
Young Adult
Title Distribution Characteristics of Air-Bone Gaps: Evidence of Bias in Manual Audiometry
URI https://www.ncbi.nlm.nih.gov/pubmed/26627469
Volume 37
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