Omaezallene from Red Alga Laurencia sp.: Structure Elucidation, Total Synthesis, and Antifouling Activity

• Published in: Angewandte Chemie International Edition Vol. 53; no. 15; pp. 3909 - 3912
• Main Authors: Umezawa, Taiki, Oguri, Yuko, Matsuura, Hiroshi, Yamazaki, Shohei, Suzuki, Masahiro, Yoshimura, Erina, Furuta, Takeshi, Nogata, Yasuyuki, Serisawa, Yukihiko, Matsuyama-Serisawa, Kazuyo, Abe, Tsuyoshi, Matsuda, Fuyuhiko, Suzuki, Minoru, Okino, Tatsufumi
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 07.04.2014; WILEY‐VCH Verlag; Wiley; Wiley Subscription Services, Inc
• Edition: International ed. in English
• Subjects: Algae; Alkadienes - chemical synthesis; Alkadienes - chemistry; allenes; Amphitrite; antifouling; Antifouling substances; Biological Products - chemical synthesis; Biological Products - chemistry; Chemistry; Chemistry, Multidisciplinary; Cypris; Hydrocarbons, Brominated - chemical synthesis; Hydrocarbons, Brominated - chemistry; Laurencia; Laurencia - chemistry; Molecular Structure; natural products; Physical Sciences; Science & Technology; structure elucidation; total synthesis; NUDIBRANCHS; allenes; natural products; ETHERS; structure elucidation; total synthesis; ABSOLUTE-CONFIGURATIONS; MARINE PLANTS; antifouling; CONSTITUENTS

Natural antifouling products have been the subject of considerable attention. We screened marine algae for antifouling activity and discovered omaezallenes, the new bromoallene‐containing natural products isolated from the red alga Laurencia sp. Described is the isolation, structure elucidation, and...