Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix‐related gene expression partly via secretion of complement factor D - Ezure, Tomonobu; Sugahara, Misato; Amano, Satoshi (BioFactors (Oxford), 2019)
Keywords: Cell Proliferation; Cellular Senescence - drug effects; CFD; Coculture Techniques; Collagen Type I - genetics; Collagen Type I - metabolism; Complement Factor D - antagonists & inhibitors; Complement Factor D - genetics; Complement Factor D - metabolism; Complement Factor D - pharmacology; Diffusion Chambers, Culture; Elastin - genetics; Elastin - metabolism; Extracellular Matrix - chemistry; Extracellular Matrix - drug effects; Extracellular Matrix - metabolism; fibroblast; Fibroblasts - cytology; Fibroblasts - drug effects; Fibroblasts - metabolism; Gene Expression Regulation; Humans; Matrix Metalloproteinase 1 - genetics; Matrix Metalloproteinase 1 - metabolism; MMP1; Primary Cell Culture; Research Communication; Research Communications; RNA, Small Interfering - genetics; RNA, Small Interfering - metabolism; SASP; senescence; Signal Transduction; CFD; senescence; fibroblast; MMP1; SASP