Micropuncture closure following high density microarray patch application in healthy subjects

• Published in: Skin research and technology Vol. 28; no. 2; pp. 305 - 310
• Main Authors: Henricson, Joakim, Muller, David A., Baker, S. Ben, Iredahl, Fredrik, Togö, Totte, Anderson, Chris D.
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.03.2022; John Wiley and Sons Inc
• Subjects: Density; evaporimetry; Health care; Healthy Volunteers; Histamine; Humans; Immunization; Inflammation; Inflammatory response; microneedles; Original; polarisation reflectance spectroscopy; Punctures; Skin; skin barrier integrity; skin reactivity; Skin resistance; Vaccination; Vaccines; Water loss; Water Loss, Insensible - physiology; microneedles; skin reactivity; skin barrier integrity; polarisation reflectance spectroscopy; evaporimetry; vaccination

Background The high‐density microarray patch (HD‐MAP) promises to be a robust vaccination platform with clear advantages for future global societal demands for health care management. The method of action has its base not only in efficient delivery of vaccine but also in the reliable induction of a...