Polyphenol-rich foods exhibit DNA antioxidative properties and protect the glutathione system in healthy subjects

• Published in: Molecular nutrition & food research Vol. 56; no. 7; pp. 1025 - 1033
• Main Authors: Pedret, Anna, Valls, Rosa M., Fernández-Castillejo, Sara, Catalán, Úrsula, Romeu, Marta, Giralt, Montserrat, Lamuela-Raventós, Rosa M., Medina-Remón, Alexander, Arija, Victoria, Aranda, Núria, Espinel, Alberto, Delgado, Marco Antonio, Solà, Rosa
• Format: Journal Article
• Language: English
• Published: Weinheim Blackwell Publishing Ltd 01.07.2012; Wiley
• Subjects: Adolescent; Adult; Age Factors; Aged; Antioxidants - administration & dosage; Antioxidants - analysis; Biological and medical sciences; Biomarkers - urine; Cross-Sectional Studies; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - urine; Diet; Diet Records; DNA Damage; DNA oxidation; Erythrocytes - metabolism; Female; Fermented food industries; Food Analysis; Food industries; Fruit and vegetable industries; Fruits; Fundamental and applied biological sciences. Psychology; Glutathione - blood; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Polyphenols - administration & dosage; Polyphenols - analysis; Polyphenols - urine; Urinary phenol excretion; Vegetables; Vitaceae; Wine; Wines and vinegars; Young Adult; Wine; Excretion; Vegetables; Fruit; Healthy subject; Urinary phenol excretion; Antioxidant; Properties; DNA oxidation; Fruits; Alcoholic beverage; Phenol; Polyphenol; DNA; Phenols; Oxidation; Food; Glutathione

Scope Polyphenols (ingested via food items) can decrease DNA, and oxidative damage of proteins and lipids. However, polyphenol effects in healthy populations have not been well defined. The aim of this study was to assess the relationship between urinary total polyphenol excretion (TPE), a biomarker...