Schwann cells apoptosis is induced by high glucose in diabetic peripheral neuropathy - Liu, Yu-pu; Shao, Shui-jin; Guo, Hai-dong (Life sciences (1973), 2020)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Animals; Apoptosis; Apoptosis - drug effects; Apoptosis - genetics; Autophagy; Autophagy - drug effects; Autophagy - genetics; beta catenin; beta Catenin - genetics; beta Catenin - metabolism; Diabetes; Diabetes mellitus; Diabetic Neuropathies - complications; Diabetic Neuropathies - genetics; Diabetic Neuropathies - metabolism; Diabetic Neuropathies - pathology; Diabetic peripheral neuropathy; Endoplasmic reticulum; endoplasmic reticulum stress; Endoplasmic Reticulum Stress - drug effects; Extracellular Signal-Regulated MAP Kinases - genetics; Extracellular Signal-Regulated MAP Kinases - metabolism; Gene Expression Regulation; Glucose; Glucose - metabolism; Glucose - pharmacology; High glucose; Humans; Hyperglycemia; Hyperglycemia - complications; Hyperglycemia - genetics; Hyperglycemia - metabolism; Hyperglycemia - pathology; Inflammation; Insulin; Insulin - metabolism; mitogen-activated protein kinase; NF-E2-Related Factor 2 - genetics; NF-E2-Related Factor 2 - metabolism; Nitrification; Oxidative stress; Oxidative Stress - drug effects; Pathogenesis; patients; peripheral nervous system diseases; Peripheral neuropathy; Phagocytosis; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-Kinases - genetics; Phosphatidylinositol 3-Kinases - metabolism; Proto-Oncogene Proteins c-akt - genetics; Proto-Oncogene Proteins c-akt - metabolism; Schwann cells; Schwann Cells - drug effects; Schwann Cells - metabolism; Schwann Cells - pathology; Signal Transduction; Signaling pathway; Wnt protein; β-Catenin; Diabetic peripheral neuropathy; Signaling pathway; Schwann cells; Apoptosis; High glucose