A Population-Based and Clinical Cohort Validation of the Novel Consensus Definition of Metabolic Hyperferritinemia

• Published in: The journal of clinical endocrinology and metabolism Vol. 109; no. 6; pp. 1540 - 1549
• Main Authors: Liu, Wen-Yue, Lian, Li-You, Zhang, Huai, Chen, Sui-Dan, Jin, Xin-Zhe, Zhang, Ni, Ye, Chen-Hui, Chen, Wen-Ying, Bee, George Goh Boon, Wang, Fu-Di, Miele, Luca, Corradini, Elena, Valenti, Luca, Zheng, Ming-Hua
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.06.2024
• Subjects: Albumin; Biopsy; Cardiovascular diseases; China; Clinical; Clinical outcomes; Comorbidity; Comparative analysis; Creatinine; Fatty liver; Ferritin; Fibrosis; Liver; Liver diseases; Metabolism; Mortality; Sarcopenia; Steatosis; Type 2 diabetes; China; metabolic syndrome; metabolic dysfunction–associated fatty liver disease; iron overload; metabolic hyperferritinemia; Iron overload; Metabolic hyperferritinemia; Metabolic syndrome; Metabolic dysfunction-associated fatty liver disease
• ISSN: 0021-972X; 1945-7197; 1945-7197
• DOI: 10.1210/clinem/dgad749

Abstract Context There is limited data on the clinical significance of metabolic hyperferritinemia (MHF) based on the most recent consensus. Objective We aimed to validate the clinical outcomes of MHF in the general population and patients with biopsy-proven metabolic dysfunction–associated fatty li...