Etiology of acute pancreatitis

Acute pancreatitis is a common disease with a benign course in the majority of patients, but it is associated with serious morbidity, and mortality close to 20% in up to 20% of cases. The incidence of acute pancreatitis seems to be rising in western countries. About 75% of all cases are caused by ga...

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Published inCentral European journal of medicine Vol. 9; no. 4; pp. 530 - 542
Main Authors Gimenez, Tomas Ratia, Calvo, Alberto Gutierrez, Vicent, Javier Granell
Format Journal Article
LanguageEnglish
Published Heidelberg Versita 01.08.2014
Walter de Gruyter GmbH
De Gruyter
Subjects
Acute pancreatitis
Biomedicine
Etiology
Guidelines
Internal Medicine
Maternal and Child Health
Medicine
Medicine & Public Health
Pathogenesis
Reproductive Medicine
Review Article
Surgery
Acute pancreatitis
Etiology
Pathogenesis
Guidelines
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Summary:Acute pancreatitis is a common disease with a benign course in the majority of patients, but it is associated with serious morbidity, and mortality close to 20% in up to 20% of cases. The incidence of acute pancreatitis seems to be rising in western countries. About 75% of all cases are caused by gallstones or alcoholism. The relative rate of gallstones versus alcohol as etiology depends on the age and the area of enrolment. A thorough evaluation allows cause identification in another 10% of cases, leaving about 15–20% as idiopathic. The most common causes, and a growing list of less frequent and sometimes very rare and controversial etiologies, are reviewed in this article. A classification on the pathogenic mechanisms of causes of acute pancreatitis based is used in this Review. The approach, or suggested plan of investigations, to determine the etiology of acute pancreatitis, based on the most recently published Guidelines is outlined.
ISSN:1895-1058
2391-5463
1644-3640
2391-5463
DOI:10.2478/s11536-013-0279-x