MicroRNAs and complex diseases: from experimental results to computational models

• Published in: Briefings in bioinformatics Vol. 20; no. 2; pp. 515 - 539
• Main Authors: Chen, Xing, Xie, Di, Zhao, Qi, You, Zhu-Hong
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 22.03.2019; Oxford Publishing Limited (England)
• Subjects: Algae; Aquatic plants; bioinformatics; Biological activity; biomedical research; Computer applications; disease diagnosis; Experimental methods; human diseases; Identification methods; Mathematical models; microRNA; MicroRNAs; miRNA; Pathogenesis; Plant viruses; prediction; State-of-the-art reviews; computational model; biological network; microRNA; complex disease; microRNA–disease association prediction; machine learning

Abstract Plenty of microRNAs (miRNAs) were discovered at a rapid pace in plants, green algae, viruses and animals. As one of the most important components in the cell, miRNAs play a growing important role in various essential and important biological processes. For the recent few decades, amounts of...