Transcriptomic Analysis from Normal Glucose Tolerance to T2D of Obese Individuals Using Bioinformatic Tools

• Published in: International journal of molecular sciences Vol. 24; no. 7; p. 6337
• Main Authors: Errafii, Khaoula, Boujraf, Said, Chikri, Mohamed
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.03.2023; MDPI
• Subjects: Adipose tissues; Blood sugar; Body fat; Cytokines; Datasets; Development and progression; Diabetes; Diabetes Mellitus, Type 2 - metabolism; Endothelial growth factors; Gene expression; Genomics; Glucose; Glucose - pharmacology; Humans; Inflammation; Insulin; Insulin - metabolism; Insulin resistance; Insulin Resistance - genetics; Kinases; Liver; Metabolism; Obesity; Obesity - metabolism; Protein kinases; Proteins; Transcriptome; Triggering Receptor Expressed on Myeloid Cells-1; Type 2 diabetes; Vascular Endothelial Growth Factor A; transcriptomics; insulin resistance; obesity; T2D

Understanding the role of white adipose tissue (WAT) in the occurrence and progression of metabolic syndrome is of considerable interest; among the metabolic syndromes are obesity and type 2 diabetes (T2D). Insulin resistance is a key factor in the development of T2D. When the target cells become re...