Hepatitis C Virus Infection in an Area Hyperendemic for Hepatitis B and Chronic Liver Disease: The Taiwan Experience

• Published in: The Journal of infectious diseases Vol. 162; no. 4; pp. 817 - 822
• Main Authors: Chen, Ding-Shinn, Kuo, George C., Sung, Juei-Low, Lai, Ming-Yang, Sheu, Jin-Chuan, Chen, Pei-Jer, Yang, Pei-Ming, Hsu, Hsu-Mei, Chang, Mei-Hwei, Chen, Chien-Jen, Hahn, Liang-Cheng, Choo, Qui-Lim, Wang, Teh-Hong, Houghton, Michael
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 01.10.1990; University of Chicago Press
• Subjects: Adult; Aged; Antibodies; Biological and medical sciences; Blood donation; Blood Donors; Carcinoma, Hepatocellular - complications; Chronic Disease; Cirrhosis; Female; General aspects; Hemophilia A - complications; Hepacivirus; Hepatitis; Hepatitis Antibodies - analysis; Hepatitis B - complications; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis C - complications; Hepatitis C - epidemiology; Hepatitis Viruses - immunology; Hepatitis, Viral, Human - epidemiology; Hepatocellular carcinoma; Humans; Infections; Infectious diseases; Liver Diseases - complications; Liver Neoplasms - complications; Major Articles; Male; Medical sciences; Middle Aged; Predisposing factors; Prevalence; Substance Abuse, Intravenous - complications; Taiwan - epidemiology; Viruses; Asia; Taiwan; Infection; Human; Non A non B viral hepatitis; Prevalence; Antibody; Immunological investigation; Viral disease; Digestive diseases; Hepatic disease; Epidemiology; In vitro; Humoral immunity

To assess the contribution of hepatitis C virus (HCV) in liver disease in Taiwan, antibody to HCV (anti-HCV) was studied by radioimmunoassay in 392 patients with chronic liver disease and in 440 healthy adults and 444 subjects at risk. The anti-HCV prevalence was 0.95% in 420 volunteer blood donors,...