Relation of central adiposity and body mass index to the development of diabetes in the Diabetes Prevention Program

BACKGROUND: Greater central adiposity is related to the risk of diabetes. OBJECTIVE: We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a better predictor of the risk of diabetes than is body mass index (BMI), waist circumference (WC), waist/hip ratio (WHR...

Full description

Saved in:
Bibliographic Details
Published inThe American journal of clinical nutrition Vol. 87; no. 5; pp. 1212 - 1218
Main Authors Bray, George A, Jablonski, Kathleen A, Fujimoto, Wilfred Y, Barrett-Connor, Elizabeth, Haffner, Steven, Hanson, Robert L, Hill, James O, Hubbard, Van, Kriska, Andrea, Stamm, Elizabeth, Pi-Sunyer, F. Xavier
Format Journal Article
LanguageEnglish
Published Bethesda, MD American Society for Nutrition 01.05.2008
American Society for Clinical Nutrition
American Society for Clinical Nutrition, Inc
Subjects
Online AccessGet full text

Cover

Loading…
Abstract BACKGROUND: Greater central adiposity is related to the risk of diabetes. OBJECTIVE: We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a better predictor of the risk of diabetes than is body mass index (BMI), waist circumference (WC), waist/hip ratio (WHR), or waist/height ratio. DESIGN: Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were measured at the L2-3 and L4-5 disc spaces in 1106 of the 3234 participants in the Diabetes Prevention Program. Sex-specific proportional hazards models were used to evaluate the association between VAT and SAT at both cuts, BMI, and other measures of central adiposity as predictors of the development of diabetes. RESULTS: Men had more VAT than did women. White subjects had more VAT at both cuts than did other ethnic groups. The ratio of VAT to SAT was lowest in African Americans of both sexes. Among men in the placebo group, VAT at both cuts, WC, BMI, waist/height ratio, and WHR predicted diabetes (hazard ratio: 1.79-1.44 per 1 SD of variable). Among women in the lifestyle group, VAT at both cuts predicted diabetes as well as did BMI, and L2-3 was a significantly better predictor than was WC or WHR. SAT did not predict diabetes. None of the body fat measurements predicted diabetes in the metformin group. CONCLUSIONS: In the placebo and lifestyle groups, VAT at both cuts, WHR, and WC predicted diabetes. No measure predicted diabetes in the metformin group. CT provided no important advantage over these simple measures. SAT did not predict diabetes.
AbstractList BACKGROUND: Greater central adiposity is related to the risk of diabetes. OBJECTIVE: We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a better predictor of the risk of diabetes than is body mass index (BMI), waist circumference (WC), waist/hip ratio (WHR), or waist/height ratio. DESIGN: Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were measured at the L2-3 and L4-5 disc spaces in 1106 of the 3234 participants in the Diabetes Prevention Program. Sex-specific proportional hazards models were used to evaluate the association between VAT and SAT at both cuts, BMI, and other measures of central adiposity as predictors of the development of diabetes. RESULTS: Men had more VAT than did women. White subjects had more VAT at both cuts than did other ethnic groups. The ratio of VAT to SAT was lowest in African Americans of both sexes. Among men in the placebo group, VAT at both cuts, WC, BMI, waist/height ratio, and WHR predicted diabetes (hazard ratio: 1.79-1.44 per 1 SD of variable). Among women in the lifestyle group, VAT at both cuts predicted diabetes as well as did BMI, and L2-3 was a significantly better predictor than was WC or WHR. SAT did not predict diabetes. None of the body fat measurements predicted diabetes in the metformin group. CONCLUSIONS: In the placebo and lifestyle groups, VAT at both cuts, WHR, and WC predicted diabetes. No measure predicted diabetes in the metformin group. CT provided no important advantage over these simple measures. SAT did not predict diabetes.
Greater central adiposity is related to the risk of diabetes. We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a better predictor of the risk of diabetes than is body mass index (BMI), waist circumference (WC), waist/hip ratio (WHR), or waist/height ratio. Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were measured at the L2-3 and L4-5 disc spaces in 1106 of the 3234 participants in the Diabetes Prevention Program. Sex-specific proportional hazards models were used to evaluate the association between VAT and SAT at both cuts, BMI, and other measures of central adiposity as predictors of the development of diabetes. Men had more VAT than did women. White subjects had more VAT at both cuts than did other ethnic groups. The ratio of VAT to SAT was lowest in African Americans of both sexes. Among men in the placebo group, VAT at both cuts, WC, BMI, waist/height ratio, and WHR predicted diabetes (hazard ratio: 1.79-1.44 per 1 SD of variable). Among women in the lifestyle group, VAT at both cuts predicted diabetes as well as did BMI, and L2-3 was a significantly better predictor than was WC or WHR. SAT did not predict diabetes. None of the body fat measurements predicted diabetes in the metformin group. In the placebo and lifestyle groups, VAT at both cuts, WHR, and WC predicted diabetes. No measure predicted diabetes in the metformin group. CT provided no important advantage over these simple measures. SAT did not predict diabetes.
Greater central adiposity is related to the risk of diabetes. We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a better predictor of the risk of diabetes than is body mass index (BMI), waist circumference (WC), waist/hip ratio (WHR), or waist/height ratio. Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were measured at the L2-3 and L4-5 disc spaces in 1106 of the 3234 participants in the Diabetes Prevention Program. Sex-specific proportional hazards models were used to evaluate the association between VAT and SAT at both cuts, BMI, and other measures of central adiposity as predictors of the development of diabetes. Men had more VAT than did women. White subjects had more VAT at both cuts than did other ethnic groups. The ratio of VAT to SAT was lowest in African Americans of both sexes. Among men in the placebo group, VAT at both cuts, WC, BMI, waist/height ratio, and WHR predicted diabetes (hazard ratio: 1.79-1.44 per 1 SD of variable). Among women in the lifestyle group, VAT at both cuts predicted diabetes as well as did BMI, and L2-3 was a significantly better predictor than was WC or WHR. SAT did not predict diabetes. None of the body fat measurements predicted diabetes in the metformin group. In the placebo and lifestyle groups, VAT at both cuts, WHR, and WC predicted diabetes. No measure predicted diabetes in the metformin group. CT provided no important advantage over these simple measures. SAT did not predict diabetes.
Author Hanson, Robert L
Stamm, Elizabeth
Haffner, Steven
Pi-Sunyer, F. Xavier
Fujimoto, Wilfred Y
Hill, James O
Bray, George A
Jablonski, Kathleen A
Hubbard, Van
Kriska, Andrea
Barrett-Connor, Elizabeth
Author_xml – sequence: 1
  fullname: Bray, George A
– sequence: 2
  fullname: Jablonski, Kathleen A
– sequence: 3
  fullname: Fujimoto, Wilfred Y
– sequence: 4
  fullname: Barrett-Connor, Elizabeth
– sequence: 5
  fullname: Haffner, Steven
– sequence: 6
  fullname: Hanson, Robert L
– sequence: 7
  fullname: Hill, James O
– sequence: 8
  fullname: Hubbard, Van
– sequence: 9
  fullname: Kriska, Andrea
– sequence: 10
  fullname: Stamm, Elizabeth
– sequence: 11
  fullname: Pi-Sunyer, F. Xavier
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20339716$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/18469241$$D View this record in MEDLINE/PubMed
BookMark eNpF0E1v1DAQBmALtaLbwpUjWEgcsx1_xfYRtXxJlVq15Ww5tlOySuzFziL23-N0FzhZ43lmRnrP0UlMMSD0hsCagGaXduPipZJrsSaU0BdoRTRTDaMgT9AKAGijSSvO0HkpGwBCuWpfojOieKspJytU7sNo5yFFnHrsQpyzHbH1wzaVYd5jGz3ukt_jyZaCh-jDbzwnPP8I2IdfYUzbqc4ss36wXZjDgp7b13_ru1xhfD5xl9NTttMrdNrbsYTXx_cCPX7-9Hj1tbm5_fLt6uNN47iCuZE9cB-sI70SoqWOSOqDaLsAvH44HZSSwvGOWyGBCN1KV3tMg5LeQccu0PvD2m1OP3ehzGaTdjnWi4ayGpPUmle0PiCXUyk59Gabh8nmvSFgloTNkrBR0gizJFwH3h637rop-P_8GGkFH47AFmfHPtvohvLPUWBMS9JW9-7gepuMfcrVfH-gQBiA0ky0kv0BLwiPyw
CODEN AJCNAC
CitedBy_id crossref_primary_10_3390_jcm12134431
crossref_primary_10_1089_met_2011_0034
crossref_primary_10_1038_oby_2009_73
crossref_primary_10_4093_dmj_2019_0174
crossref_primary_10_1210_jendso_bvaa164
crossref_primary_10_1111_jcpe_13288
crossref_primary_10_1155_2017_9707284
crossref_primary_10_1016_j_metabol_2009_03_001
crossref_primary_10_1093_pm_pnaa426
crossref_primary_10_2337_db23_0131
crossref_primary_10_1007_s00247_011_2021_7
crossref_primary_10_3945_ajcn_2009_28136
crossref_primary_10_3390_nu15194112
crossref_primary_10_1007_s12020_013_0154_1
crossref_primary_10_4093_dmj_2017_41_6_486
crossref_primary_10_1002_msj_20112
crossref_primary_10_1007_s11695_013_0925_z
crossref_primary_10_26416_Med_157_1_2024_9459
crossref_primary_10_1111_jog_12364
crossref_primary_10_1371_journal_pone_0024017
crossref_primary_10_1530_ERC_12_0393
crossref_primary_10_3109_08037051_2010_538996
crossref_primary_10_1007_s00125_018_4748_2
crossref_primary_10_1134_S2079057013030107
crossref_primary_10_1097_TP_0000000000003881
crossref_primary_10_1007_s11606_018_4436_4
crossref_primary_10_1136_bmjopen_2015_009266
crossref_primary_10_1093_abbs_gmx113
crossref_primary_10_1097_FJC_0000000000001131
crossref_primary_10_1177_1479164111416139
crossref_primary_10_2147_DMSO_S299171
crossref_primary_10_2337_dc08_1881
crossref_primary_10_3390_nu15153394
crossref_primary_10_1038_oby_2009_180
crossref_primary_10_1080_13557858_2014_921890
crossref_primary_10_3390_nu12010244
crossref_primary_10_1097_MCO_0b013e32831b9c5b
crossref_primary_10_1186_1471_2458_10_234
crossref_primary_10_1093_ajcn_87_5_1118
crossref_primary_10_1016_j_diabet_2013_04_001
crossref_primary_10_1080_20905068_2019_1658340
crossref_primary_10_1093_ajcn_nqz309
crossref_primary_10_1016_j_diabres_2011_08_018
crossref_primary_10_1016_j_nutres_2010_08_007
crossref_primary_10_1016_j_diabres_2023_110561
crossref_primary_10_1016_j_dsx_2018_03_027
crossref_primary_10_1371_journal_pone_0152559
crossref_primary_10_1016_j_endonu_2010_06_009
crossref_primary_10_3109_14767058_2014_936003
crossref_primary_10_7717_peerj_cs_1896
crossref_primary_10_1111_j_1751_7176_2011_00565_x
crossref_primary_10_3945_ajcn_113_071712
crossref_primary_10_1002_oby_20459
crossref_primary_10_1155_2014_697264
crossref_primary_10_1017_S1368980013002668
crossref_primary_10_1155_2012_567320
crossref_primary_10_1038_ijo_2009_134
crossref_primary_10_1016_j_thromres_2015_05_033
crossref_primary_10_1111_ctr_13040
crossref_primary_10_1210_jc_2017_00967
crossref_primary_10_4158_EP161365_GL
crossref_primary_10_1016_j_dsx_2018_11_017
crossref_primary_10_1016_j_pmrj_2017_08_436
crossref_primary_10_1097_MD_0000000000027114
crossref_primary_10_5551_jat_12294
crossref_primary_10_3389_fendo_2019_00449
crossref_primary_10_1177_0145721711411107
crossref_primary_10_1111_prd_12239
crossref_primary_10_1007_s40519_017_0467_9
crossref_primary_10_1016_j_metabol_2016_11_008
crossref_primary_10_1155_2023_5015572
crossref_primary_10_1111_j_1399_5448_2009_00512_x
crossref_primary_10_1038_s41598_019_53056_x
crossref_primary_10_1111_jgs_13376
crossref_primary_10_1186_1472_6823_13_7
crossref_primary_10_23921_amp_2021v5i2_00046
crossref_primary_10_1016_j_artmed_2014_08_005
crossref_primary_10_1115_1_4024491
crossref_primary_10_7705_biomedica_v32i4_799
crossref_primary_10_4236_ojpm_2018_81002
crossref_primary_10_3389_fpubh_2023_1159024
crossref_primary_10_1590_1806_9282_20220978
crossref_primary_10_56936_18290825_2022_16_2_91
crossref_primary_10_2169_internalmedicine_50_4292
crossref_primary_10_2337_dc09_0943
crossref_primary_10_1111_ajt_15784
crossref_primary_10_33790_jrpr1100126
crossref_primary_10_1042_BCJ20190472
crossref_primary_10_5402_2012_534085
crossref_primary_10_1016_j_anai_2012_07_017
crossref_primary_10_1038_s41598_020_73631_x
crossref_primary_10_1002_ijgo_12202
crossref_primary_10_4162_nrp_2013_7_1_43
crossref_primary_10_1002_nbm_4817
crossref_primary_10_1016_j_nut_2009_09_001
crossref_primary_10_1016_j_transproceed_2022_03_058
crossref_primary_10_1017_S1368980010002648
crossref_primary_10_1242_dmm_008912
crossref_primary_10_1111_obr_12335
crossref_primary_10_1097_MCO_0b013e32831fd97a
crossref_primary_10_1038_nutd_2010_2
crossref_primary_10_3945_jn_109_118737
crossref_primary_10_1038_aps_2011_167
crossref_primary_10_1007_s11695_020_05082_2
crossref_primary_10_1111_j_1532_5415_2010_03018_x
crossref_primary_10_1016_j_jnutbio_2011_02_005
crossref_primary_10_1016_j_gie_2011_07_006
crossref_primary_10_1016_j_phrs_2023_106860
crossref_primary_10_1007_s12160_010_9238_9
crossref_primary_10_1177_1054773817740547
crossref_primary_10_2183_pjab_88_454
crossref_primary_10_2337_dc10_0744
crossref_primary_10_1016_j_mayocp_2016_12_020
crossref_primary_10_1016_j_genm_2009_02_002
crossref_primary_10_1038_oby_2009_388
crossref_primary_10_1186_s12933_018_0734_8
crossref_primary_10_1007_s11695_024_07208_2
crossref_primary_10_1007_s00394_015_1066_z
crossref_primary_10_1001_jamanetworkopen_2018_1493
crossref_primary_10_2217_dmt_11_22
crossref_primary_10_1080_01443615_2024_2329880
crossref_primary_10_1038_emm_2016_5
crossref_primary_10_1111_obr_13393
crossref_primary_10_3998_circus_2801
crossref_primary_10_1089_met_2009_0089
crossref_primary_10_1111_j_1748_1716_2009_02010_x
crossref_primary_10_1002_oby_20705
crossref_primary_10_1007_s13679_015_0149_8
crossref_primary_10_1590_S0103_05822011000400012
crossref_primary_10_1017_S0954422410000144
crossref_primary_10_1093_ndt_gfac152
crossref_primary_10_1016_j_archger_2010_04_010
crossref_primary_10_1111_dote_12271
crossref_primary_10_1186_1472_6823_13_42
crossref_primary_10_1007_s00247_010_1880_7
crossref_primary_10_1017_S0954422409990096
crossref_primary_10_1152_physrev_00033_2011
crossref_primary_10_1097_gme_0b013e3182703b73
crossref_primary_10_1053_j_gastro_2010_04_056
crossref_primary_10_5402_2012_947323
crossref_primary_10_1186_s12880_019_0393_6
crossref_primary_10_2337_dc09_0290
crossref_primary_10_1016_j_physbeh_2016_04_047
crossref_primary_10_1007_s40265_015_0416_8
crossref_primary_10_1177_1474651411407418
crossref_primary_10_1210_jc_2012_4106
crossref_primary_10_1111_tri_13547
crossref_primary_10_1016_S0140_6736_23_01517_9
crossref_primary_10_1111_obr_12551
crossref_primary_10_1586_erc_10_13
crossref_primary_10_20463_pan_2021_0026
crossref_primary_10_1161_ATVBAHA_111_241893
crossref_primary_10_2217_whe_15_62
crossref_primary_10_3389_fimmu_2021_670566
crossref_primary_10_1002_ajhb_23413
crossref_primary_10_1093_gerona_glx163
crossref_primary_10_1111_jog_14887
crossref_primary_10_1515_hmbci_2018_0014
crossref_primary_10_1111_ajt_16322
crossref_primary_10_1210_js_2019_00069
crossref_primary_10_1111_j_1741_2358_2010_00411_x
crossref_primary_10_1249_MSS_0000000000002509
crossref_primary_10_1186_1758_5996_2_30
crossref_primary_10_1111_jhn_12089
crossref_primary_10_1016_j_gtc_2023_03_001
crossref_primary_10_1590_S0004_27302010000300008
crossref_primary_10_1152_ajpheart_00593_2012
crossref_primary_10_1186_1475_2840_8_22
crossref_primary_10_1016_j_cjca_2015_06_017
crossref_primary_10_1038_srep40389
crossref_primary_10_12717_DR_2017_21_3_259
crossref_primary_10_1007_s11892_015_0675_5
crossref_primary_10_1038_s42003_022_03503_9
crossref_primary_10_1089_bar_2010_9994
crossref_primary_10_2147_DMSO_S432331
crossref_primary_10_1016_j_trsl_2014_05_008
Cites_doi 10.1016/0026-0495(87)90063-1
10.2337/diacare.17.9.961
10.2337/diacare.23.11.1619
10.1016/0002-9149(94)90676-9
10.1111/j.1464-5491.2004.01391.x
10.1152/jappl.2000.89.2.636
10.1056/NEJM200105033441801
10.1016/S0026-0495(99)90033-1
10.1093/ajcn/81.3.555
10.2337/diab.46.3.456
10.1016/0895-4356(91)90044-A
10.1093/ajcn/61.4.765
10.2337/diab.34.10.1055
10.2337/diab.39.3.283
10.2337/diab.35.4.411
10.1093/ajcn/4.1.20
10.1038/sj.ijo.0801414
10.1093/oxfordjournals.aje.a009158
10.1002/j.1550-8528.1997.tb00278.x
10.2337/diacare.22.4.623
10.2337/diacare.20.4.537
10.1210/jcem-54-2-254
10.1002/(SICI)1096-9136(199712)14:5+3.0.CO;2-R
10.1016/0091-7435(83)90244-X
10.1002/sim.1802
10.2337/diacare.27.5.1047
10.2337/diab.18.7.478
10.1093/ajcn/48.6.1351
10.1136/bmj.311.6998.158
10.1038/oby.2006.246
10.2307/2531595
10.1056/NEJMoa012512
10.2337/diab.38.3.304
10.1016/S0026-0495(96)90011-6
10.1093/ajcn/69.3.381
ContentType Journal Article
Copyright 2008 INIST-CNRS
Copyright American Society for Clinical Nutrition, Inc. May 1, 2008
Copyright_xml – notice: 2008 INIST-CNRS
– notice: Copyright American Society for Clinical Nutrition, Inc. May 1, 2008
CorporateAuthor Diabetes Prevention Program Research Group
CorporateAuthor_xml – name: Diabetes Prevention Program Research Group
DBID FBQ
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7QP
7T7
7TS
8FD
C1K
FR3
K9.
NAPCQ
P64
DOI 10.1093/ajcn/87.5.1212
DatabaseName AGRIS
Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Calcium & Calcified Tissue Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
Physical Education Index
Technology Research Database
Environmental Sciences and Pollution Management
Engineering Research Database
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Premium
Biotechnology and BioEngineering Abstracts
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Nursing & Allied Health Premium
Technology Research Database
ProQuest Health & Medical Complete (Alumni)
Engineering Research Database
Industrial and Applied Microbiology Abstracts (Microbiology A)
Calcium & Calcified Tissue Abstracts
Physical Education Index
Biotechnology and BioEngineering Abstracts
Environmental Sciences and Pollution Management
DatabaseTitleList
Nursing & Allied Health Premium
MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: FBQ
  name: AGRIS
  url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN
  sourceTypes: Publisher
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Diet & Clinical Nutrition
EISSN 1938-3207
EndPage 1218
ExternalDocumentID 1484739271
10_1093_ajcn_87_5_1212
18469241
20339716
US201300893567
Genre Research Support, U.S. Gov't, P.H.S
Research Support, N.I.H., Intramural
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Journal Article
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: NIDDK NIH HHS
  grantid: U01 DK048489
– fundername: NIDDK NIH HHS
  grantid: P30 DK072476
– fundername: NIDDK NIH HHS
  grantid: U01 DK048489-06
– fundername: Intramural NIH HHS
GroupedDBID ---
-ET
-~X
..I
.55
.GJ
0R~
1HT
23M
2FS
2WC
3O-
4.4
476
48X
53G
5GY
5RE
5VS
6J9
85S
8R4
8R5
A8Z
AABJS
AABMN
AABZA
AACZT
AAIKC
AAJQQ
AAMNW
AAPGJ
AAPQZ
AAUQX
AAUTI
AAVAP
AAWDT
AAWTL
AAXUO
AAYOK
ABBTP
ABDNZ
ABJNI
ABLJU
ABOCM
ABPTD
ABSAR
ABSGY
ABWST
ACFRR
ACGFO
ACGFS
ACGOD
ACIMA
ACNCT
ACPRK
ACPVT
ACUFI
ACUTJ
ADBBV
ADEIU
ADGZP
ADHUB
ADRTK
ADVEK
AEGXH
AENEX
AEQTP
AETBJ
AFDAS
AFFDN
AFFNX
AFFZL
AFMIJ
AFOFC
AFRAH
AFXAL
AGINJ
AGNAY
AGQXC
AGUTN
AHMBA
AI.
AIAGR
AIKOY
AIMBJ
AJEEA
ALMA_UNASSIGNED_HOLDINGS
ALXQX
AMRAJ
ANFBD
AQDSO
AQKUS
ASMCH
AZQFJ
BAWUL
BAYMD
BCRHZ
BEYMZ
BKOMP
BTRTY
BYORX
C1A
CASEJ
CDBKE
DAKXR
DIK
DPPUQ
E3Z
EBS
EIHJH
EJD
ENERS
EX3
F5P
F9R
FBQ
FDB
FECEO
FOTVD
FQBLK
FRP
G8K
GAUVT
GJXCC
GX1
HF~
HZ~
I4R
IH2
J5H
KBUDW
KOP
KQ8
KSI
KSN
L7B
LPU
MBLQV
MHKGH
MV1
MVM
N4W
NEJ
NHB
NHCRO
NOMLY
NOYVH
NVLIB
O9-
OAUYM
OBFPC
ODMLO
OHT
OJZSN
OK1
OPAEJ
OVD
P2P
P6G
PCD
PQQKQ
PRG
Q2X
R0Z
RHF
RHI
RNS
ROL
ROX
SJN
SV3
TCN
TEORI
TMA
TNT
TR2
TWZ
UBH
UHB
UKR
VH1
W2D
W8F
WH7
WHG
WOQ
WOW
X7M
XOL
XSW
YBU
YHG
YOJ
YQJ
YRY
YSK
YV5
YYQ
YZZ
ZA5
ZCA
ZCG
ZGI
ZUP
ZXP
~KM
08R
AAUGY
AKALU
H13
IQODW
0SF
AAHBH
AALRI
ADUKH
ADVLN
AFJKZ
AFRQD
AGKRT
AITUG
AKRWK
CGR
CUY
CVF
ECM
EIF
FLUFQ
FOEOM
NPM
AAYXX
ABDPE
CITATION
7QP
7T7
7TS
8FD
C1K
FR3
K9.
NAPCQ
P64
ID FETCH-LOGICAL-c480t-7f04deac1f85562c172de56be04855c9e8875c4b4a57015967cbe039087dc0b3
ISSN 0002-9165
IngestDate Thu Oct 10 20:22:38 EDT 2024
Thu Nov 21 23:10:58 EST 2024
Sat Sep 28 08:17:33 EDT 2024
Sun Oct 22 16:06:22 EDT 2023
Wed Dec 27 19:18:39 EST 2023
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 5
Keywords Endocrinopathy
Human
Prevention
Body mass index
Adiposity
Diabetes mellitus
Development
Language English
License CC BY 4.0
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c480t-7f04deac1f85562c172de56be04855c9e8875c4b4a57015967cbe039087dc0b3
OpenAccessLink https://doi.org/10.1093/ajcn/87.5.1212
PMID 18469241
PQID 231937994
PQPubID 41076
PageCount 7
ParticipantIDs proquest_journals_231937994
crossref_primary_10_1093_ajcn_87_5_1212
pubmed_primary_18469241
pascalfrancis_primary_20339716
fao_agris_US201300893567
PublicationCentury 2000
PublicationDate 2008-05-01
PublicationDateYYYYMMDD 2008-05-01
PublicationDate_xml – month: 05
  year: 2008
  text: 2008-05-01
  day: 01
PublicationDecade 2000
PublicationPlace Bethesda, MD
PublicationPlace_xml – name: Bethesda, MD
– name: United States
– name: Bethesda
PublicationTitle The American journal of clinical nutrition
PublicationTitleAlternate Am J Clin Nutr
PublicationYear 2008
Publisher American Society for Nutrition
American Society for Clinical Nutrition
American Society for Clinical Nutrition, Inc
Publisher_xml – name: American Society for Nutrition
– name: American Society for Clinical Nutrition
– name: American Society for Clinical Nutrition, Inc
References 18469227 - Am J Clin Nutr. 2008 May;87(5):1118-9
Lachin (10.1093/ajcn/87.5.1212_bib32) 2000
Wang (10.1093/ajcn/87.5.1212_bib21) 2005; 81
Ohlson (10.1093/ajcn/87.5.1212_bib11) 1985; 34
Vague (10.1093/ajcn/87.5.1212_bib7) 1956; 4
Kaye (10.1093/ajcn/87.5.1212_bib19) 1991; 44
Chan (10.1093/ajcn/87.5.1212_bib20) 1994; 17
(10.1093/ajcn/87.5.1212_bib6) 2002; 346
McAlpine (10.1093/ajcn/87.5.1212_bib2) 2005; 22
(10.1093/ajcn/87.5.1212_bib27) 1999; 22
Despres (10.1093/ajcn/87.5.1212_bib14) 1989; 38
Hartz (10.1093/ajcn/87.5.1212_bib10) 1983; 12
Pan (10.1093/ajcn/87.5.1212_bib4) 1997; 20
(10.1093/ajcn/87.5.1212_bib28) 2000; 23
Carey (10.1093/ajcn/87.5.1212_bib17) 1997; 145
Hill (10.1093/ajcn/87.5.1212_bib38) 1999; 69
Perry (10.1093/ajcn/87.5.1212_bib40) 2000; 89
Okosun (10.1093/ajcn/87.5.1212_bib41) 2000; 24
Kotani (10.1093/ajcn/87.5.1212_bib25) 1994; 18
Pencina (10.1093/ajcn/87.5.1212_bib33) 2004; 23
Amos (10.1093/ajcn/87.5.1212_bib3) 1997; 14
Kissebah (10.1093/ajcn/87.5.1212_bib9) 1982; 54
Lohman (10.1093/ajcn/87.5.1212_bib30) 1988
Marcus (10.1093/ajcn/87.5.1212_bib39) 1999; 48
Tuomilehto (10.1093/ajcn/87.5.1212_bib5) 2001; 344
Wei (10.1093/ajcn/87.5.1212_bib18) 1997; 5
10.1093/ajcn/87.5.1212_bib26
Lean (10.1093/ajcn/87.5.1212_bib22) 1995; 311
Holm (10.1093/ajcn/87.5.1212_bib31) 1979; 6
DeLong (10.1093/ajcn/87.5.1212_bib34) 1988; 44
Conway (10.1093/ajcn/87.5.1212_bib36) 1995; 61
Kvist (10.1093/ajcn/87.5.1212_bib24) 1988; 48
Wing (10.1093/ajcn/87.5.1212_bib29) 2004; 12
Albu (10.1093/ajcn/87.5.1212_bib35) 1997; 46
Haffner (10.1093/ajcn/87.5.1212_bib16) 1990; 39
Lundgren (10.1093/ajcn/87.5.1212_bib15) 1989; 13
Pouliot (10.1093/ajcn/87.5.1212_bib23) 1994; 73
Lovejoy (10.1093/ajcn/87.5.1212_bib37) 1996; 45
Feldman (10.1093/ajcn/87.5.1212_bib8) 1969; 18
Fujioka (10.1093/ajcn/87.5.1212_bib13) 1987; 36
Sparrow (10.1093/ajcn/87.5.1212_bib12) 1986; 35
Wild (10.1093/ajcn/87.5.1212_bib1) 2004; 27
References_xml – volume: 36
  start-page: 54
  year: 1987
  ident: 10.1093/ajcn/87.5.1212_bib13
  article-title: Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity.
  publication-title: Metabolism
  doi: 10.1016/0026-0495(87)90063-1
  contributor:
    fullname: Fujioka
– volume: 17
  start-page: 961
  issue: 9
  year: 1994
  ident: 10.1093/ajcn/87.5.1212_bib20
  article-title: Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men.
  publication-title: Diabetes Care
  doi: 10.2337/diacare.17.9.961
  contributor:
    fullname: Chan
– volume: 23
  start-page: 1619
  year: 2000
  ident: 10.1093/ajcn/87.5.1212_bib28
  article-title: The Diabetes Prevention Program Research Group.
  publication-title: Diabetes Care
  doi: 10.2337/diacare.23.11.1619
– volume: 73
  start-page: 460
  issue: 7
  year: 1994
  ident: 10.1093/ajcn/87.5.1212_bib23
  article-title: Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women.
  publication-title: Am J Cardiol
  doi: 10.1016/0002-9149(94)90676-9
  contributor:
    fullname: Pouliot
– volume: 22
  start-page: 348
  issue: 3
  year: 2005
  ident: 10.1093/ajcn/87.5.1212_bib2
  article-title: The annual incidence of diabetic complications in a population of patients with type 1 and type 2 diabetes.
  publication-title: Diabet Med
  doi: 10.1111/j.1464-5491.2004.01391.x
  contributor:
    fullname: McAlpine
– volume: 89
  start-page: 636
  issue: 2
  year: 2000
  ident: 10.1093/ajcn/87.5.1212_bib40
  article-title: Racial differences in visceral adipose tissue but not anthropometric markers of health-related variables.
  publication-title: J Appl Physiol
  doi: 10.1152/jappl.2000.89.2.636
  contributor:
    fullname: Perry
– volume: 18
  start-page: 207
  year: 1994
  ident: 10.1093/ajcn/87.5.1212_bib25
  article-title: Sexual dimorphism of age-related changes in whole-body fat distribution in the obese.
  publication-title: Int J Obes Relat Metab Disord
  contributor:
    fullname: Kotani
– volume: 344
  start-page: 1343
  year: 2001
  ident: 10.1093/ajcn/87.5.1212_bib5
  article-title: Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.
  publication-title: N Engl J Med
  doi: 10.1056/NEJM200105033441801
  contributor:
    fullname: Tuomilehto
– volume: 12
  start-page: 1426
  issue: 9
  year: 2004
  ident: 10.1093/ajcn/87.5.1212_bib29
  article-title: Obes Res
  publication-title: Obes Res
  contributor:
    fullname: Wing
– volume: 48
  start-page: 194
  issue: 4
  year: 1999
  ident: 10.1093/ajcn/87.5.1212_bib39
  article-title: Insulin sensitivity and serum triglyceride level in obese white and black women: relationship to visceral and truncal subcutaneous fat.
  publication-title: Metabolism
  doi: 10.1016/S0026-0495(99)90033-1
  contributor:
    fullname: Marcus
– volume: 81
  start-page: 555
  issue: 3
  year: 2005
  ident: 10.1093/ajcn/87.5.1212_bib21
  article-title: Comparison of abdominal adiposity and overall obeity in predicting risk of type 2 diabetes among men.
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/81.3.555
  contributor:
    fullname: Wang
– volume: 46
  start-page: 456
  issue: 3
  year: 1997
  ident: 10.1093/ajcn/87.5.1212_bib35
  article-title: Visceral fat and race-dependent health risks in obese nondiabetic premenopausal women.
  publication-title: Diabetes
  doi: 10.2337/diab.46.3.456
  contributor:
    fullname: Albu
– volume: 44
  start-page: 329
  issue: 3
  year: 1991
  ident: 10.1093/ajcn/87.5.1212_bib19
  article-title: Increased incidence of diabetes mellitus in relation to abdominal adiposity in older women.
  publication-title: J Clin Epidemiol
  doi: 10.1016/0895-4356(91)90044-A
  contributor:
    fullname: Kaye
– volume: 61
  start-page: 765
  issue: 4
  year: 1995
  ident: 10.1093/ajcn/87.5.1212_bib36
  article-title: Visceral adipose tissue differences in black and white women.
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/61.4.765
  contributor:
    fullname: Conway
– volume: 6
  start-page: 5
  year: 1979
  ident: 10.1093/ajcn/87.5.1212_bib31
  article-title: A simple sequentially rejective multiple test procedure.
  publication-title: Scand J Stat
  contributor:
    fullname: Holm
– year: 1988
  ident: 10.1093/ajcn/87.5.1212_bib30
  contributor:
    fullname: Lohman
– volume: 34
  start-page: 1055
  year: 1985
  ident: 10.1093/ajcn/87.5.1212_bib11
  article-title: The influence of body fat distribution on the incidence of diabetes mellitus. 13.5 years of follow-up of the participants in the study of men born in 1913.
  publication-title: Diabetes
  doi: 10.2337/diab.34.10.1055
  contributor:
    fullname: Ohlson
– volume: 13
  start-page: 413
  year: 1989
  ident: 10.1093/ajcn/87.5.1212_bib15
  article-title: Adiposity and adipose tissue distribution in relation to incidence of diabetes in women: results from a prospective population study in Gothenburg, Sweden.
  publication-title: Int J Obes
  contributor:
    fullname: Lundgren
– volume: 39
  start-page: 283
  year: 1990
  ident: 10.1093/ajcn/87.5.1212_bib16
  article-title: Incidence of type II diabetes in Mexican Americans predicted by fasting insulin and glucose levels, obesity and body fat distribution.
  publication-title: Diabetes
  doi: 10.2337/diab.39.3.283
  contributor:
    fullname: Haffner
– volume: 35
  start-page: 411
  year: 1986
  ident: 10.1093/ajcn/87.5.1212_bib12
  article-title: Relationship of fat distribution to glucose tolerance.
  publication-title: Diabetes
  doi: 10.2337/diab.35.4.411
  contributor:
    fullname: Sparrow
– volume: 4
  start-page: 20
  year: 1956
  ident: 10.1093/ajcn/87.5.1212_bib7
  article-title: The degree of masculine differentiation of obesities determining predisposition to diabetes, atherosclerosis, gout and uric calculus disease.
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/4.1.20
  contributor:
    fullname: Vague
– volume: 24
  start-page: 1279
  issue: 10
  year: 2000
  ident: 10.1093/ajcn/87.5.1212_bib41
  article-title: Abdominal adiposity values associated with established body mass indexes in white, black and Hispanic Americans. A study from the Third National Health and Nutrition Examination Survey.
  publication-title: Int J Obes Relat Metab Disord
  doi: 10.1038/sj.ijo.0801414
  contributor:
    fullname: Okosun
– volume: 145
  start-page: 614
  year: 1997
  ident: 10.1093/ajcn/87.5.1212_bib17
  article-title: Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study.
  publication-title: Am J Epidemiol
  doi: 10.1093/oxfordjournals.aje.a009158
  contributor:
    fullname: Carey
– volume: 5
  start-page: 16
  issue: 1
  year: 1997
  ident: 10.1093/ajcn/87.5.1212_bib18
  article-title: Waist circumference as the best predictor of non-insulin dependent diabetes mellitus (NIDDM) compared to body mass index, waist/hip ratio and other anthropometric measurements in Mexican Americans—a 7-year prospective study.
  publication-title: Obes Res
  doi: 10.1002/j.1550-8528.1997.tb00278.x
  contributor:
    fullname: Wei
– volume: 22
  start-page: 623
  issue: 4
  year: 1999
  ident: 10.1093/ajcn/87.5.1212_bib27
  article-title: Design and methods for a clinical trial in the prevention of type 2 diabetes.
  publication-title: Diabetes Care
  doi: 10.2337/diacare.22.4.623
– volume: 20
  start-page: 537
  year: 1997
  ident: 10.1093/ajcn/87.5.1212_bib4
  article-title: Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Zing IGT and Diabetes Study.
  publication-title: Diabetes Care
  doi: 10.2337/diacare.20.4.537
  contributor:
    fullname: Pan
– volume: 54
  start-page: 254
  year: 1982
  ident: 10.1093/ajcn/87.5.1212_bib9
  article-title: Relation of body fat distribution to metabolic complications of obesity.
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jcem-54-2-254
  contributor:
    fullname: Kissebah
– volume: 14
  start-page: 81
  year: 1997
  ident: 10.1093/ajcn/87.5.1212_bib3
  article-title: The rising global burden of diabetes and its complications: estimates and projections to the year 2010.
  publication-title: Diabet Med
  doi: 10.1002/(SICI)1096-9136(199712)14:5+3.0.CO;2-R
  contributor:
    fullname: Amos
– volume: 12
  start-page: 351
  year: 1983
  ident: 10.1093/ajcn/87.5.1212_bib10
  article-title: Relationship of obesity to diabetes: influence of obesity level and body fat distribution.
  publication-title: Prev Med
  doi: 10.1016/0091-7435(83)90244-X
  contributor:
    fullname: Hartz
– volume: 23
  start-page: 2109
  year: 2004
  ident: 10.1093/ajcn/87.5.1212_bib33
  article-title: Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation.
  publication-title: Stat Med
  doi: 10.1002/sim.1802
  contributor:
    fullname: Pencina
– volume: 27
  start-page: 1047
  year: 2004
  ident: 10.1093/ajcn/87.5.1212_bib1
  article-title: Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.
  publication-title: Diabetes Care
  doi: 10.2337/diacare.27.5.1047
  contributor:
    fullname: Wild
– year: 2000
  ident: 10.1093/ajcn/87.5.1212_bib32
  contributor:
    fullname: Lachin
– volume: 18
  start-page: 478
  year: 1969
  ident: 10.1093/ajcn/87.5.1212_bib8
  article-title: Difference in diabetic and nondiabetic fat distribution patterns by skinfold measurements.
  publication-title: Diabetes
  doi: 10.2337/diab.18.7.478
  contributor:
    fullname: Feldman
– volume: 48
  start-page: 1351
  year: 1988
  ident: 10.1093/ajcn/87.5.1212_bib24
  article-title: Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations.
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/48.6.1351
  contributor:
    fullname: Kvist
– volume: 311
  start-page: 158
  issue: 6998
  year: 1995
  ident: 10.1093/ajcn/87.5.1212_bib22
  article-title: Waist circumference as a measure for indicating need for weight management.
  publication-title: BMJ
  doi: 10.1136/bmj.311.6998.158
  contributor:
    fullname: Lean
– ident: 10.1093/ajcn/87.5.1212_bib26
  doi: 10.1038/oby.2006.246
– volume: 44
  start-page: 837
  issue: 3
  year: 1988
  ident: 10.1093/ajcn/87.5.1212_bib34
  article-title: Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach.
  publication-title: Biometrics
  doi: 10.2307/2531595
  contributor:
    fullname: DeLong
– volume: 346
  start-page: 393
  year: 2002
  ident: 10.1093/ajcn/87.5.1212_bib6
  article-title: Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa012512
– volume: 38
  start-page: 304
  year: 1989
  ident: 10.1093/ajcn/87.5.1212_bib14
  article-title: Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women.
  publication-title: Diabetes
  doi: 10.2337/diab.38.3.304
  contributor:
    fullname: Despres
– volume: 45
  start-page: 1119
  issue: 9
  year: 1996
  ident: 10.1093/ajcn/87.5.1212_bib37
  article-title: Abdominal fat distribution and metabolic risk factors: effects of race.
  publication-title: Metabolism
  doi: 10.1016/S0026-0495(96)90011-6
  contributor:
    fullname: Lovejoy
– volume: 69
  start-page: 381
  issue: 3
  year: 1999
  ident: 10.1093/ajcn/87.5.1212_bib38
  article-title: Racial differences in amounts of visceral adipose tissue in young adults: the CARDIA (Coronary Artery Risk Development in Young Adults) Study.
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/69.3.381
  contributor:
    fullname: Hill
SSID ssj0012486
Score 2.4280407
Snippet BACKGROUND: Greater central adiposity is related to the risk of diabetes. OBJECTIVE: We aimed to test the hypothesis that central adiposity measured by...
Greater central adiposity is related to the risk of diabetes. We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a...
Greater central adiposity is related to the risk of diabetes. We aimed to test the hypothesis that central adiposity measured by computed tomography (CT) is a...
SourceID proquest
crossref
pubmed
pascalfrancis
fao
SourceType Aggregation Database
Index Database
Publisher
StartPage 1212
SubjectTerms abdominal fat
adipose tissue
Adult
adults
Biological and medical sciences
Body Composition - physiology
Body fat
Body Height - physiology
Body Mass Index
Diabetes
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - prevention & control
Diabetes Prevention Program
Disease prevention
drug therapy
Ethnicity
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Humans
Hypoglycemic Agents - therapeutic use
Intra-Abdominal Fat - anatomy & histology
Intra-Abdominal Fat - diagnostic imaging
Life Style
lifestyle
Lumbar Vertebrae
Male
Measurement
metformin
Metformin - therapeutic use
Middle Aged
Obesity - complications
Obesity - therapy
prediction
Predictive Value of Tests
Primary Prevention
Proportional Hazards Models
Risk
Risk Factors
Sex Factors
subcutaneous fat
Subcutaneous Fat - anatomy & histology
Subcutaneous Fat - diagnostic imaging
Time Factors
Tomography, X-Ray Computed - methods
Vertebrates: anatomy and physiology, studies on body, several organs or systems
visceral fat
waist circumference
Waist-Hip Ratio
waist-to-hip ratio
Title Relation of central adiposity and body mass index to the development of diabetes in the Diabetes Prevention Program
URI https://www.ncbi.nlm.nih.gov/pubmed/18469241
https://www.proquest.com/docview/231937994
Volume 87
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwGLW6ISFeEIzLwmDyA4KHKl2a-JI8AmUaQ5uQ6KS9RYljT522ZlrTh_F7-KF8vsXZYBLwErVxElc9J_6O7ePPCL0teCoFy1XMIXbERGR1nIuGxqxKaFqpaZ2ZdWtHx-zghBye0tPR6OfAtbTu6on48cd1Jf-DKpwDXPUq2X9Atn8onIDPgC8cAWE4_hXG3slmvOF2mHZcNQtjxLJ5leq2uRlfgkAem7SIXmk2wSqk7-0HYJ3pcea_-wRPUMU3a-Qaitl5WJWyHKag6FdbLn2q_8HM_U0YiQ_jqIdVfdH6LbS9wSMU76_PNaXMqC40Y0p75nsJ_tGajWOzcfb1XataGNLIg4FwIm0zXEAznKV2P1zfTrvAvBjOhJtGd5paJ_Zv0cBmyqrOhY54OZ_Qyd1LAc-rS8MO6Oky6ItOQ1zs3Yq-aAM90OkW9Q4Nsy9f-7mqlOSsTwea7enq9vrKdFJad_st5bOhqlb7cKsVwKHsHir3d3KM2Jk_QY9dLwV_sJR7ikZyuYWi2UJ2-B12qWQv8LGHdws9PHIejWdo5VmJW4UdK3HPSgysxJqVWLMSG1birsVAOzxgpb7XsxIuMsWelTiwEjtWPkfz_c_zTwex29ojFiRPupirhDQQ86cqp6DABcjoRlJWy0QnKxKFhNhHBalJRTkI1oJxAWVZkeS8EUmdvUCby3YptxFmpGGN5KohVBKZsjpXSVJxRUEXC5VMI_Te_-vllU3gUlrjRVZqqMqcl7TUUEVoG0ApqzOIruXJ91TP6Scg5ynjEdq9hVT_pDTJMp2ELUI7HrrSvW-rErpOIP6LgkTopUUz_ALHiVf3luygR-HVeI02u-u1fAP6t6t3Df1-AWvkskc
link.rule.ids 314,780,784,27924,27925
linkProvider Flying Publisher
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Relation+of+central+adiposity+and+body+mass+index+to+the+development+of+diabetes+in+the+Diabetes+Prevention+Program&rft.jtitle=The+American+journal+of+clinical+nutrition&rft.au=Bray%2C+George+A&rft.au=Jablonski%2C+Kathleen+A&rft.au=Fujimoto%2C+Wilfred+Y&rft.au=Barrett-Connor%2C+Elizabeth&rft.date=2008-05-01&rft.eissn=1938-3207&rft.volume=87&rft.issue=5&rft.spage=1212&rft_id=info:doi/10.1093%2Fajcn%2F87.5.1212&rft_id=info%3Apmid%2F18469241&rft.externalDocID=18469241
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0002-9165&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0002-9165&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0002-9165&client=summon