Cannabinoid modulation of brain activation during volitional regulation of negative affect in trauma-exposed adults

• Published in: Neuropharmacology Vol. 218; p. 109222
• Main Authors: Pacitto, Regina, Peters, Craig, Iadipaolo, Allesandra, Rabinak, Christine A.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.11.2022
• Subjects: Adult; Brain; Cannabinoids; Dronabinol - pharmacology; Dronabinol - therapeutic use; Emotions - physiology; Humans; Magnetic Resonance Imaging; Stress Disorders, Post-Traumatic - diagnostic imaging; Stress Disorders, Post-Traumatic - drug therapy

Emotion dysregulation is considered a core component of posttraumatic stress disorder (PTSD). Cognitive reappraisal is one therapeutic emotion regulation strategy that has been widely studied among individuals with mood and anxiety disorders, and numerous differences in brain activation patterns hav...