Experimental evolution reveals hidden diversity in evolutionary pathways

• Published in: eLife Vol. 4
• Main Authors: Lind, Peter A, Farr, Andrew D, Rainey, Paul B
• Format: Journal Article
• Language: English
• Published: England eLife Sciences Publications Ltd 25.03.2015; eLife Sciences Publications, Ltd
• Subjects: bacterial evolution; Bias; Biological Evolution; c-di-GMP; diguanylate cyclase; Directed Molecular Evolution; Evolution; Evolution & development; evolutionary rule; evolutionary rules; Experiments; Gene Fusion; genetic constraint; Genetic Fitness; Genomes; Genomics and Evolutionary Biology; Mutation; Mutation - genetics; parallel evolution; Phenotype; Population; Promoter Regions, Genetic - genetics; Pseudomonas fluorescens - genetics; Pseudomonas fluorescens SBW25; RNA, Messenger - genetics; RNA, Messenger - metabolism; Transcription, Genetic; diguanylate cyclase; parallel evolution; evolutionary biology; genetic constraint; bacterial evolution; genomics; Pseudomonas fluorescens; evolutionary rules

Replicate populations of natural and experimental organisms often show evidence of parallel genetic evolution, but the causes are unclear. The wrinkly spreader morph of Pseudomonas fluorescens arises repeatedly during experimental evolution. The mutational causes reside exclusively within three path...