Evolution and molecular interactions of major histocompatibility complex (MHC)-G, -E and -F genes

• Published in: Cellular and molecular life sciences : CMLS Vol. 79; no. 8; p. 464
• Main Authors: Arnaiz-Villena, Antonio, Suarez-Trujillo, Fabio, Juarez, Ignacio, Rodríguez-Sainz, Carmen, Palacio-Gruber, José, Vaquero-Yuste, Christian, Molina-Alejandre, Marta, Fernández-Cruz, Eduardo, Martin-Villa, José Manuel
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.08.2022; Springer Nature B.V
• Subjects: Alleles; Animal models; Antigens; Apes; Associations; Biochemistry; Biomedical and Life Sciences; Biomedicine; Cell Biology; Chromosomes; Coevolution; complement; Complement component C4; Evolution; Evolutionary genetics; Genes; Genetic markers; Haplotypes; Histocompatibility antigen HLA; HLA antigens; humans; Immunomodulation; Leukocytes; Life Sciences; Lymphocytes T; Major histocompatibility complex; Modulation; Molecular interactions; Natural killer cells; Orthology; Pathogenesis; Receptors; Review; statistics; T cell receptors; Haplotypes; Apes; Disease; Complotypes; MHC; Evolution; Monkeys; HLA-F; HLA; HLA-G; HLA-E

Classical HLA (Human Leukocyte Antigen) is the Major Histocompatibility Complex (MHC) in man. HLA genes and disease association has been studied at least since 1967 and no firm pathogenic mechanisms have been established yet. HLA-G immune modulation gene (and also -E and -F ) are starting the same a...