Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid - Lleó, Alberto; Núñez-Llaves, Raúl; Alcolea, Daniel; Chiva, Cristina; Balateu-Paños, Daniel; Colom-Cadena, Martí; Gomez-Giro, Gemma; Muñoz, Laia; Querol-Vilaseca, Marta; Pegueroles, Jordi; Rami, Lorena; Lladó, Albert; et al. (Molecular & cellular proteomics, 2019)
Keywords: Aged; Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - metabolism; Alzheimer's disease; Autopsy; Biomarker: Prognostic; Biomarkers - cerebrospinal fluid; Biomarkers - metabolism; Calcium-Binding Proteins - cerebrospinal fluid; Calcium-Binding Proteins - metabolism; Cerebrospinal fluid; Clinical proteomics; Early Diagnosis; Female; Humans; Male; Nerve Tissue Proteins - cerebrospinal fluid; Nerve Tissue Proteins - metabolism; Prodromal Symptoms; Prognosis; Proteomics - methods; Receptors, AMPA - metabolism; Selected reaction monitoring; Synapses - metabolism; Syntaxin 1 - cerebrospinal fluid; Syntaxin 1 - metabolism; Thy-1 Antigens - cerebrospinal fluid; Thy-1 Antigens - metabolism; Biomarker: Prognostic; Cerebrospinal fluid; Selected reaction monitoring; Clinical proteomics; Alzheimer's disease