Matrix Metalloproteinase-9 Is Increased in Obese Subjects and Decreases in Response to Pioglitazone - Unal, Resat; Yao-Borengasser, Aiwei; Varma, Vijayalakshmi; Rasouli, Neda; Labbate, Craig; Kern, Philip A.; Ranganathan, Gouri (The journal of clinical endocrinology and metabolism, 2010)
Keywords: Abdominal wall; Adipocytes; Adipocytes - drug effects; Adipocytes - enzymology; Adipose tissue; Adipose Tissue - enzymology; Adult; Aged; Biological and medical sciences; Biopsy; Blotting, Western; Body fat; Body Mass Index; Cells, Cultured; Coculture Techniques; Endocrinopathies; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Gelatinase B; Glucose; Glucose tolerance; Humans; Hypoglycemic Agents - therapeutic use; Insulin Resistance; Kinases; Macrophages; Male; Matrix metalloproteinase; Matrix Metalloproteinase 9 - biosynthesis; Matrix Metalloproteinase 9 - metabolism; Matrix Metalloproteinase Inhibitors; Medical sciences; Metalloproteinase; Metformin; Middle Aged; mRNA; Obesity; Obesity - enzymology; Oligonucleotides - metabolism; Original; Pioglitazone; Protein kinase C; Protein Kinase C-alpha - metabolism; Research design; Reverse Transcriptase Polymerase Chain Reaction; RNA - biosynthesis; RNA - genetics; Sensitivity analysis; Stromal Cells - drug effects; Stromal Cells - enzymology; Th1 Cells - drug effects; Th1 Cells - enzymology; Thiazolidinediones - therapeutic use; Transfection; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Vertebrates: endocrinology; Young Adult; Human; Obesity; Nutrition; Enzyme; Pioglitazone; Nutrition disorder; Metalloendopeptidases; Metabolic diseases; Thiazolidinedione derivatives; Gelatinase B; Peptidases; Hypoglycemic agent; Hydrolases; Endocrinology; Nutritional status