Phosphaturic mesenchymal tumors. A polymorphous group causing osteomalacia or rickets

• Published in: Cancer Vol. 59; no. 8; pp. 1442 - 1454
• Main Authors: Weidner, Noel, Cruz, Daniel Santa
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 15.04.1987; Wiley-Liss
• Subjects: Adult; Biological and medical sciences; Bone Neoplasms - pathology; Female; Fibroma - pathology; Follow-Up Studies; Histocytochemistry; Humans; Immunoenzyme Techniques; Male; Medical sciences; Mesenchymoma - pathology; Mesenchymoma - secondary; Microscopy, Electron; Middle Aged; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Osteoma, Osteoid - pathology; Osteomalacia - pathology; Osteomalacia - urine; Phosphates - urine; Rickets - pathology; Rickets - urine; Syndrome; Tumors; Vimentin - analysis; Metabolic disorder; Rickets; Diseases of the osteoarticular system; Tumor; Bone disease; Soft tissue; Osteomalacia

Reported are the pathologic features of 17 mesenchymal tumors documented as causing osteomalacia or rickets. Although these tumors were histologically polymorphous, they were classifiable into four morphological groups. In the first group there were ten unique tumors showing mixed connective tissue...