Prospective study of long-term pulmonary manifestations of mantle irradiation

• Published in: International journal of radiation oncology, biology, physics Vol. 19; no. 3; pp. 707 - 714
• Main Authors: Shapiro, Susan J., Shapiro, Steven D., Mill, William B., Campbell, Edward J.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.09.1990; Elsevier
• Subjects: 560151 - Radiation Effects on Animals- Man; Adolescent; Adult; Aged; Biological and medical sciences; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; BODY AREAS; CHEST; Chest radiographs; DISEASES; Diseases of the respiratory system; Dysgerminoma - diagnostic imaging; Dysgerminoma - epidemiology; Dysgerminoma - radiotherapy; Expiratory Reserve Volume - radiation effects; Female; Functional Residual Capacity - radiation effects; Gas exchange; Hodgkin Disease - diagnostic imaging; Hodgkin Disease - epidemiology; Hodgkin Disease - radiotherapy; Hodgkin's disease; HODGKINS DISEASE; Humans; IMMUNE SYSTEM DISEASES; Lung - radiation effects; Lymphoma, Follicular - diagnostic imaging; Lymphoma, Follicular - epidemiology; Lymphoma, Follicular - radiotherapy; LYMPHOMAS; Male; Mediastinal Neoplasms - diagnostic imaging; Mediastinal Neoplasms - epidemiology; Mediastinal Neoplasms - radiotherapy; MEDIASTINUM; Medical sciences; MEDICINE; Middle Aged; NEOPLASMS; NUCLEAR MEDICINE; PATIENTS; Prospective Studies; Pulmonary function studies; Pulmonary Gas Exchange - radiation effects; RADIATION EFFECTS; Radiation therapy; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT; RADIOINDUCTION; RADIOLOGY; Radionuclide Imaging; RADIOTHERAPY; Radiotherapy - adverse effects; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Respiratory Mechanics - radiation effects; RESPIRATORY SYSTEM; RESPIRATORY SYSTEM DISEASES; SIDE EFFECTS; THERAPY; Time Factors; Ventilation-perfusion scans; Vital Capacity - radiation effects; Radiation therapy; Chest radiographs; Gas exchange; Pulmonary function studies; Ventilation-perfusion scans; Hodgkin's disease; Human; Tumor; Treatment; Radiotherapy; Respiratory disease; Lung

Given the high cure rate of patients with Hodgkin's disease, the complications related to therapy take on great significance. Mantle irradiation to the thorax is used in virtually all patients with early stage Hodgkin's disease. Prior studies of patients receiving mantle irradiation demons...