Nucleophosmin 1: from its pathogenic role to a tantalizing therapeutic target in acute myeloid leukemia
Nucleophosmin 1 (NPM1, also known as B23) is a multifunctional protein involved in a variety of cellular processes, including ribosomal maturation, centrosome replication, maintenance of genomic stability, cell cycle control, and apoptosis. NPM1 is the most commonly mutated gene in adult acute myelo...
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Published in | Hematology (Luxembourg) Vol. 27; no. 1; pp. 609 - 619 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
Taylor & Francis
31.12.2022
Taylor & Francis Group |
Subjects | |
Online Access | Get full text |
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