Dopaminergic Genes Predict Individual Differences in Susceptibility to Confirmation Bias

• Published in: The Journal of neuroscience Vol. 31; no. 16; pp. 6188 - 6198
• Main Authors: Doll, Bradley B., Hutchison, Kent E., Frank, Michael J.
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 20.04.2011
• Subjects: Adult; Catechol O-Methyltransferase - genetics; Catechol O-Methyltransferase - metabolism; Cognition - physiology; Corpus Striatum - metabolism; Dopamine - genetics; Dopamine - metabolism; Dopamine and cAMP-Regulated Phosphoprotein 32 - genetics; Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism; Female; Genotype; Humans; Individuality; Learning - physiology; Male; Models, Psychological; Neuropsychological Tests; Polymorphism, Genetic; Prefrontal Cortex - metabolism

The striatum is critical for the incremental learning of values associated with behavioral actions. The prefrontal cortex (PFC) represents abstract rules and explicit contingencies to support rapid behavioral adaptation in the absence of cumulative experience. Here we test two alternative models of...