Gut microbiota in systemic lupus erythematosus: A fuse and a solution

• Published in: Journal of Autoimmunity Vol. 132; p. 102867
• Main Authors: Chen, Yanfei, Lin, Jin, Xiao, Lanlan, Zhang, Xuan, Zhao, Lidan, Wang, Min, Li, Lanjuan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.10.2022; Elsevier BV
• Subjects: Autoantibodies; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Gut microbiome; Humans; Immune response; Inflammation; Lupus Erythematosus, Systemic; Systemic lupus erythematosus; Gut microbiome; Systemic lupus erythematosus; Immune response

Gut commensals help shape and mold host immune system and deeply influence human health. The disease spectrum of mankind that gut microbiome may associate with is ever-growing, but the mechanisms are still enigmas. Characterized by loss of self-tolerance and sustained self-attack, systemic lupus ery...