Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers
Modafinil, a putative cognitive enhancing drug, has previously been shown to improve performance of healthy volunteers as well as patients with attention deficit disorder and schizophrenia, mainly in tests of executive functions. The aim of this study was to investigate the effects of modafinil on n...
Saved in:
Published in | Neuropharmacology Vol. 64; no. 5; pp. 490 - 495 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.01.2013
Pergamon Press |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Modafinil, a putative cognitive enhancing drug, has previously been shown to improve performance of healthy volunteers as well as patients with attention deficit disorder and schizophrenia, mainly in tests of executive functions. The aim of this study was to investigate the effects of modafinil on non-verbal cognitive functions in healthy volunteers, with a particular focus on variations of cognitive load, measures of motivational factors and the effects on creative problem-solving.
A double-blind placebo-controlled parallel design study evaluated the effect of 200 mg of modafinil (N = 32) or placebo (N = 32) in non-sleep deprived healthy volunteers. Non-verbal tests of divergent and convergent thinking were used to measure creativity. A new measure of task motivation was used, together with more levels of difficulty on neuropsychological tests from the CANTAB battery.
Improvements under modafinil were seen on spatial working memory, planning and decision making at the most difficult levels, as well as visual pattern recognition memory following delay. Subjective ratings of enjoyment of task performance were significantly greater under modafinil compared with placebo, but mood ratings overall were not affected. The effects of modafinil on creativity were inconsistent and did not reach statistical significance.
Modafinil reliably enhanced task enjoyment and performance on several cognitive tests of planning and working memory, but did not improve paired associates learning. The findings confirm that modafinil can enhance aspects of highly demanding cognitive performance in non-sleep deprived individuals.
This article is part of a Special Issue entitled ‘Cognitive Enhancers’.
► Subjective ratings of task performance enjoyment were greater under modafinil. ► Modafinil enhanced performance on cognitive tests of planning and working memory. ► Modafinil can enhance demanding cognitive performance in non-sleep deprived people. |
---|---|
AbstractList | ► Subjective ratings of task performance enjoyment were greater under modafinil. ► Modafinil enhanced performance on cognitive tests of planning and working memory. ► Modafinil can enhance demanding cognitive performance in non-sleep deprived people. Modafinil, a putative cognitive enhancing drug, has previously been shown to improve performance of healthy volunteers as well as patients with attention deficit disorder and schizophrenia, mainly in tests of executive functions. The aim of this study was to investigate the effects of modafinil on non-verbal cognitive functions in healthy volunteers, with a particular focus on variations of cognitive load, measures of motivational factors and the effects on creative problem-solving. A double-blind placebo-controlled parallel design study evaluated the effect of 200 mg of modafinil (N = 32) or placebo (N = 32) in non-sleep deprived healthy volunteers. Non-verbal tests of divergent and convergent thinking were used to measure creativity. A new measure of task motivation was used, together with more levels of difficulty on neuropsychological tests from the CANTAB battery. Improvements under modafinil were seen on spatial working memory, planning and decision making at the most difficult levels, as well as visual pattern recognition memory following delay. Subjective ratings of enjoyment of task performance were significantly greater under modafinil compared with placebo, but mood ratings overall were not affected. The effects of modafinil on creativity were inconsistent and did not reach statistical significance. Modafinil reliably enhanced task enjoyment and performance on several cognitive tests of planning and working memory, but did not improve paired associates learning. The findings confirm that modafinil can enhance aspects of highly demanding cognitive performance in non-sleep deprived individuals. This article is part of a Special Issue entitled ‘Cognitive Enhancers’. ► Subjective ratings of task performance enjoyment were greater under modafinil. ► Modafinil enhanced performance on cognitive tests of planning and working memory. ► Modafinil can enhance demanding cognitive performance in non-sleep deprived people. Modafinil, a putative cognitive enhancing drug, has previously been shown to improve performance of healthy volunteers as well as patients with attention deficit disorder and schizophrenia, mainly in tests of executive functions. The aim of this study was to investigate the effects of modafinil on non-verbal cognitive functions in healthy volunteers, with a particular focus on variations of cognitive load, measures of motivational factors and the effects on creative problem-solving. A double-blind placebo-controlled parallel design study evaluated the effect of 200 mg of modafinil (N = 32) or placebo (N = 32) in non-sleep deprived healthy volunteers. Non-verbal tests of divergent and convergent thinking were used to measure creativity. A new measure of task motivation was used, together with more levels of difficulty on neuropsychological tests from the CANTAB battery. Improvements under modafinil were seen on spatial working memory, planning and decision making at the most difficult levels, as well as visual pattern recognition memory following delay. Subjective ratings of enjoyment of task performance were significantly greater under modafinil compared with placebo, but mood ratings overall were not affected. The effects of modafinil on creativity were inconsistent and did not reach statistical significance. Modafinil reliably enhanced task enjoyment and performance on several cognitive tests of planning and working memory, but did not improve paired associates learning. The findings confirm that modafinil can enhance aspects of highly demanding cognitive performance in non-sleep deprived individuals. This article is part of a Special Issue entitled 'Cognitive Enhancers'. |
Author | Müller, U. Rowe, J.B. Robbins, T.W. Rittman, T. Lewis, C. Sahakian, B.J. |
AuthorAffiliation | a Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK e Oxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, UK b MRC/Wellcome Trust Behavioural and Clinical Neuroscience Institute (BCNI), University of Cambridge, Cambridge, UK d Department of Experimental Psychology, Downing Street, University of Cambridge, Cambridge, UK c Department of Clinical Neuroscience, University of Cambridge School of Clinical Medicine, Cambridge, UK |
AuthorAffiliation_xml | – name: a Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK – name: d Department of Experimental Psychology, Downing Street, University of Cambridge, Cambridge, UK – name: e Oxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, UK – name: b MRC/Wellcome Trust Behavioural and Clinical Neuroscience Institute (BCNI), University of Cambridge, Cambridge, UK – name: c Department of Clinical Neuroscience, University of Cambridge School of Clinical Medicine, Cambridge, UK |
Author_xml | – sequence: 1 givenname: U. surname: Müller fullname: Müller, U. organization: Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK – sequence: 2 givenname: J.B. surname: Rowe fullname: Rowe, J.B. organization: MRC/Wellcome Trust Behavioural and Clinical Neuroscience Institute (BCNI), University of Cambridge, Cambridge, UK – sequence: 3 givenname: T. surname: Rittman fullname: Rittman, T. organization: Department of Clinical Neuroscience, University of Cambridge School of Clinical Medicine, Cambridge, UK – sequence: 4 givenname: C. surname: Lewis fullname: Lewis, C. organization: Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK – sequence: 5 givenname: T.W. surname: Robbins fullname: Robbins, T.W. organization: MRC/Wellcome Trust Behavioural and Clinical Neuroscience Institute (BCNI), University of Cambridge, Cambridge, UK – sequence: 6 givenname: B.J. surname: Sahakian fullname: Sahakian, B.J. email: bjs1001@cam.ac.uk, bjs-sec@medschl.cam.ac.uk organization: Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22820554$$D View this record in MEDLINE/PubMed |
BookMark | eNqFkc1u1DAQx62qFd0WXqHyA5AwTuJkckGCqlCkSlzK2XLi8cbbxF453kj79k210MKJ0xzm_zH6zRU798ETY1xALkDUn3a5p0MM-0HHKS9AFDk0OUB7xjYCmzJroK7O2QagwKxsAS_Z1TzvAKBCge_YZVFgAVJWGzbcWUt9mnmwfApGW-fdyIPna2O2UOz0yPuw9S654D_ypOcnTn4XjhP5xLU3vI-kk1uIp8H5J-e33Hk-kB7TcORLGA8-EcX5Pbuwepzpw-95zX59u3u8vc8efn7_cfvlIeurpk2ZkR1KhKI0NRXYIZVIPeoWDSC1tpLSirrUAkppqbPQdSjIGK2xbk2FXXnNPp9y94duItOvZ0Y9qn10k45HFbRT_268G9Q2LKqsUMq6XAPwFNDHMM-R7KtXgHqhr3bqjb56oa-gUSv91Xrzd_er8Q_uVfD1JKCVwOIoqrl35HsyLq5fUCa4_7c8A18Godw |
CitedBy_id | crossref_primary_10_1097_JCP_0000000000001085 crossref_primary_10_3389_fphar_2018_01189 crossref_primary_10_1016_j_neuroimage_2019_116279 crossref_primary_10_1093_ijnp_pyx112 crossref_primary_10_1016_j_neuroimage_2013_07_038 crossref_primary_10_1177_0269881116668591 crossref_primary_10_1007_s12152_014_9222_3 crossref_primary_10_1007_s41465_024_00288_z crossref_primary_10_1042_ETLS20220008 crossref_primary_10_1007_s00213_019_05250_y crossref_primary_10_1177_0091450918789415 crossref_primary_10_1177_0269881113508173 crossref_primary_10_3389_fpsyg_2015_01852 crossref_primary_10_1080_09687637_2019_1593318 crossref_primary_10_1080_10826084_2018_1552297 crossref_primary_10_1093_brain_awab429 crossref_primary_10_1002_hbm_25949 crossref_primary_10_1007_s13311_020_00849_y crossref_primary_10_1126_science_aad5893 crossref_primary_10_1186_s12910_016_0102_8 crossref_primary_10_1111_hequ_12201 crossref_primary_10_1016_j_neuropharm_2013_07_038 crossref_primary_10_1080_15265161_2013_794881 crossref_primary_10_1093_milmed_usab398 crossref_primary_10_1016_j_neuropharm_2017_07_031 crossref_primary_10_1093_brain_awz137 crossref_primary_10_2196_21703 crossref_primary_10_1002_hup_2700 crossref_primary_10_1080_17449642_2018_1443050 crossref_primary_10_1007_s00213_022_06149_x crossref_primary_10_1016_j_bbr_2017_06_023 crossref_primary_10_1177_2398212818816018 crossref_primary_10_1002_14651858_CD010843_pub2 crossref_primary_10_1016_S2215_0366_15_00004_8 crossref_primary_10_1016_j_neuropharm_2017_08_020 crossref_primary_10_4236_ojpsych_2018_81008 crossref_primary_10_1038_s41598_021_03372_y crossref_primary_10_1111_bcp_13885 crossref_primary_10_1007_s00106_020_00927_9 crossref_primary_10_1177_0269881114555252 crossref_primary_10_1007_s00213_020_05625_6 crossref_primary_10_1016_j_bpsc_2016_11_009 crossref_primary_10_18273_revmed_v33n1_2020004 crossref_primary_10_1007_s00213_017_4650_5 crossref_primary_10_1016_j_bandc_2021_105802 crossref_primary_10_1111_1468_2230_12056 crossref_primary_10_1016_j_jddst_2016_12_012 crossref_primary_10_1016_j_addbeh_2014_02_015 crossref_primary_10_1007_s00213_013_3186_6 crossref_primary_10_1080_08897077_2019_1700584 crossref_primary_10_1007_s00213_015_4007_x crossref_primary_10_1007_s12144_023_04703_0 crossref_primary_10_2139_ssrn_2592354 crossref_primary_10_1007_s00213_013_3232_4 crossref_primary_10_1016_j_euroneuro_2020_07_002 crossref_primary_10_1016_j_neuroscience_2014_08_014 crossref_primary_10_1016_j_euroneuro_2015_07_028 crossref_primary_10_1093_jmp_jhy040 crossref_primary_10_1111_dar_12294 crossref_primary_10_1007_s00213_015_4038_3 crossref_primary_10_1124_jpet_116_236000 crossref_primary_10_1017_S0033291717000885 crossref_primary_10_1075_aila_27_04mac crossref_primary_10_1016_j_cobeha_2015_04_010 crossref_primary_10_3389_fphar_2019_00682 crossref_primary_10_13005_bpj_1776 crossref_primary_10_1007_s10111_022_00715_1 crossref_primary_10_1016_j_cobeha_2015_05_007 crossref_primary_10_31338_2657_599X_ph_2021_2_1 crossref_primary_10_1016_j_cobeha_2015_05_004 crossref_primary_10_1016_j_neubiorev_2014_04_002 crossref_primary_10_1590_0004_282X20150140 crossref_primary_10_5665_sleep_3480 crossref_primary_10_1101_lm_040345_115 crossref_primary_10_1111_nyas_13040 crossref_primary_10_1038_s41386_020_0625_z crossref_primary_10_1056_NEJMoa1701131 crossref_primary_10_1080_14740338_2020_1698545 crossref_primary_10_1016_j_tics_2024_04_007 crossref_primary_10_1007_s40265_022_01701_7 crossref_primary_10_1016_j_nicl_2017_04_026 crossref_primary_10_1016_j_bioet_2017_05_001 crossref_primary_10_1016_j_euroneuro_2017_01_006 crossref_primary_10_1016_j_tine_2019_02_001 crossref_primary_10_1111_bph_13813 crossref_primary_10_1002_clc_22678 crossref_primary_10_1007_s11569_018_0332_y crossref_primary_10_1098_rstb_2014_0214 |
Cites_doi | 10.2174/1874473710801020213 10.1007/s00213-008-1395-1 10.1016/0361-476X(81)90035-7 10.1016/j.pbb.2005.07.019 10.1056/NEJMoa041292 10.1016/j.appet.2003.11.003 10.1097/FJC.0b013e318195a470 10.1111/j.2044-8341.1976.tb02388.x 10.1016/0028-3932(94)00098-A 10.1016/j.neuropharm.2012.07.011 10.1007/s00213-008-1369-3 10.1586/14737175.6.4.455 10.1016/j.neuropsychologia.2011.03.037 10.1037/0022-3514.37.8.1398 10.1016/j.smrv.2004.03.002 10.1007/s002130051102 10.1176/appi.ajp.2009.09050613 10.1177/0269881109106926 10.1007/s00213-005-0044-1 10.1159/000051269 10.1159/000074081 10.1016/j.phrs.2010.04.002 10.1007/s00213-004-1926-3 10.1007/s00213-010-1823-x 10.1007/s00213-002-1080-8 10.1007/BF02244990 10.1038/sj.npp.1300457 10.1016/j.paid.2009.01.018 10.1007/s00213-011-2472-4 10.1002/j.1552-4604.1998.tb04425.x 10.1126/science.1164908 10.1038/sj.npp.1301534 10.1177/0269881109105899 10.1207/s15326934crj0904_8 10.1016/S0006-3223(03)00609-7 10.1017/S146114571100037X 10.1017/S1355617798455073 10.1111/j.2044-8341.1974.tb02285.x 10.1016/0028-3932(90)90137-D 10.1007/s00213-002-1250-8 |
ContentType | Journal Article |
Copyright | 2012 Elsevier Ltd Copyright © 2012 Elsevier Ltd. All rights reserved. 2013 Elsevier Ltd. 2012 Elsevier Ltd |
Copyright_xml | – notice: 2012 Elsevier Ltd – notice: Copyright © 2012 Elsevier Ltd. All rights reserved. – notice: 2013 Elsevier Ltd. 2012 Elsevier Ltd |
DBID | 6I. AAFTH CGR CUY CVF ECM EIF NPM AAYXX CITATION 5PM |
DOI | 10.1016/j.neuropharm.2012.07.009 |
DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef PubMed Central (Full Participant titles) |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Pharmacy, Therapeutics, & Pharmacology |
EISSN | 1873-7064 |
EndPage | 495 |
ExternalDocumentID | 10_1016_j_neuropharm_2012_07_009 22820554 S0028390812003449 |
Genre | Randomized Controlled Trial Research Support, Non-U.S. Gov't Journal Article |
GrantInformation_xml | – fundername: Medical Research Council grantid: G1100464 – fundername: Wellcome Trust grantid: 086041 – fundername: Medical Research Council grantid: MC_U105597119 – fundername: Wellcome Trust grantid: 0886041/Z/08/Z – fundername: Wellcome Trust grantid: 088324 – fundername: Wellcome Trust grantid: 093875 – fundername: Medical Research Council grantid: G1000183 – fundername: Medical Research Council grantid: G0001354 – fundername: Wellcome Trust grantid: 093875/Z/10/Z |
GroupedDBID | --- --K --M -~X .55 .GJ .~1 0R~ 123 1B1 1RT 1~. 1~5 29N 3O- 4.4 41~ 457 4G. 53G 5RE 5VS 6I. 7-5 71M 8P~ 9JM AABNK AACTN AADPK AAEDT AAEDW AAFTH AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATCM AAXLA AAXUO ABCQJ ABFNM ABFRF ABIVO ABJNI ABMAC ABXDB ABYKQ ABZDS ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADIYS ADMUD AEBSH AEFWE AEKER AENEX AFKWA AFTJW AFXIZ AGHFR AGUBO AGWIK AGYEJ AHHHB AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC C45 CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HMQ HMT HVGLF HZ~ IHE J1W K-O KOM L7B M2V M34 M41 MO0 MOBAO N9A O-L O9- OAUVE OGGZJ OVD OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SCC SDF SDG SDP SES SEW SNS SPCBC SPT SSN SSP SSZ T5K TEORI WUQ X7M XOL ZGI ZXP ~G- AKRWK CGR CUY CVF ECM EIF NPM AAXKI AAYXX CITATION 5PM |
ID | FETCH-LOGICAL-c479t-d5b858023d6e28b8e38ec8a98d08e9f455f163a1035febf0bb81eddaa869d48b3 |
IEDL.DBID | .~1 |
ISSN | 0028-3908 |
IngestDate | Tue Sep 17 21:21:25 EDT 2024 Thu Sep 12 16:30:14 EDT 2024 Tue Aug 27 13:45:52 EDT 2024 Fri Feb 23 02:30:52 EST 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 5 |
Keywords | Executive functions Cognitive enhancer Modafinil Motivation Memory Creative thinking |
Language | English |
License | http://creativecommons.org/licenses/by/3.0 Copyright © 2012 Elsevier Ltd. All rights reserved. Open Access under CC BY 3.0 license |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c479t-d5b858023d6e28b8e38ec8a98d08e9f455f163a1035febf0bb81eddaa869d48b3 |
OpenAccessLink | https://www.sciencedirect.com/science/article/pii/S0028390812003449 |
PMID | 22820554 |
PageCount | 6 |
ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_3485563 crossref_primary_10_1016_j_neuropharm_2012_07_009 pubmed_primary_22820554 elsevier_sciencedirect_doi_10_1016_j_neuropharm_2012_07_009 |
PublicationCentury | 2000 |
PublicationDate | January 2013 2013-Jan 2013-01-00 20130101 |
PublicationDateYYYYMMDD | 2013-01-01 |
PublicationDate_xml | – month: 01 year: 2013 text: January 2013 |
PublicationDecade | 2010 |
PublicationPlace | England |
PublicationPlace_xml | – name: England |
PublicationTitle | Neuropharmacology |
PublicationTitleAlternate | Neuropharmacology |
PublicationYear | 2013 |
Publisher | Elsevier Ltd Pergamon Press |
Publisher_xml | – name: Elsevier Ltd – name: Pergamon Press |
References | Owen, Sahakian, Semple, Polkey, Robbins (bib29) 1995; 33 Makris, Rush, Frederich, Kelly (bib18) 2004; 42 Mehta, Sahakian, McKenna, Robbins (bib20) 1999; 146 Swainson, Hodges, Galton, Semple, Michael, Dunn, Iddon, Robbins, Sahakian (bib40) 2001; 12 Benerjee, Vitiellob, Grunsteinc (bib2) 2004; 8 Farah, Caroline, Sankoorikal, Smith, Chatterjee (bib10) 2009; 203 Winder-Rhodes, Chamberlaine, Idris, Robbins, Sahakian, Müller (bib46) 2010; 24 Sahakian, Morein-Zamir (bib34) 2011; 25 Wong, King, Laughton, McCormick, Grebow (bib48) 1998; 38 Wechsler (bib45) 1981; 6 Turner (bib43) 2006; 6 Witkin, Oltman, Raskin (bib47) 2002 Minzenberg, Carter (bib21) 2008; 33 Noppe (bib27) 1996; 9 Randall, Shneerson, File (bib31) 2005; 82 Martínez-Raga, Knecht, Cepeda (bib19) 2008; 1 Scoriels, L., Jones, P.B., Sahakian, B.J. Modafinil effects on cognition and emotion in schizophrenia and its neurochemical modulation in the brain. Neuropharmacology, in press. de Rover, Pironti, McCabe, Acosta-Cabronero, Arana, Morein-Zamir, Hodges, Robbins, Fletcher, Nestor, Sahakian (bib8) 2011; 49 Deroche-Gamonet, Darnaudéry, Bruins-Slot, Piat, Le Moal, Piazza (bib9) 2002; 161 Repantis, Schlattmann, Laisney, Heuser (bib32) 2010; 62 Provigil (bib30) 1997 Herbert, Johns, Dore (bib14) 1976; 49 Lezak, Howieson, Loring (bib16) 2004 Scoriels, Barnett, Soma, Sahakian, Jones (bib36) 2012; 220 Nelson, Willison (bib26) 1991 Blackwell, Sahakian, Vesey, Semple, Robbins, Hodges (bib3) 2004; 17 Sahakian, Owen (bib35) 1992; 85 Morgan, Pace-Schott, Pittman, Stickgold, Malison (bib24) 2010; 167 Czeisler, Walsh, Roth, Hughes, Wright, Kingsbury, Arora, Schwartz, Niebler, Dinges, U.S. Modafinil in Shift Work Sleep Disorder Study Group (bib7) 2005; 353 Goff (bib12) 2002 CANTABeclipse (bib5) 2011 Robbins, James, Owen, Sahakian, Lawrence, McInnes, Rabbitt (bib33) 1998; 4 Stoops, Lile, Fillmore, Glaser, Rush (bib39) 2005; 182 Lynch, Regan, Stump, Tannenbaum, Stevens, Bone, Gilberto, Johnson, Fujino, Takenaga, Tokita, Nagase, Sato, Renger (bib15) 2009; 53 Marchant, Kamel, Echlin, Grice, Lewis, Rusted (bib17) 2009; 202 Müller, Steffenhagen, Regenthal, Bublak (bib25) 2004; 177 Turner, Clark, Pomarol-Clotet, McKenna, Robbins, Sahakian (bib42) 2004; 29 Minzenberg, Watrous, Yoon, Ursu, Carter (bib22) 2008; 322 Finke, Dodds, Bublak, Regenthal, Baumann, Manly, Müller (bib11) 2010; 210 Claridge, McDonald (bib6) 2009; 49 Turner, Robbins, Clark, Aron, Dowson, Sahakian (bib41) 2003; 165 Owen, Downes, Sahakian, Polkey, Robbins (bib28) 1990; 28 Wallach, Kogan (bib44) 1965 Simon, Panissaud, Costentin (bib38) 1994; 114 Mohamed, Sahakian (bib23) 2012; 15 Aron, Dowson, Sahakian, Robbins (bib1) 2003; 54 Gough (bib13) 1979; 37 Bond, Lader (bib4) 1974; 47 Owen (10.1016/j.neuropharm.2012.07.009_bib28) 1990; 28 Deroche-Gamonet (10.1016/j.neuropharm.2012.07.009_bib9) 2002; 161 Lynch (10.1016/j.neuropharm.2012.07.009_bib15) 2009; 53 Turner (10.1016/j.neuropharm.2012.07.009_bib43) 2006; 6 Marchant (10.1016/j.neuropharm.2012.07.009_bib17) 2009; 202 Swainson (10.1016/j.neuropharm.2012.07.009_bib40) 2001; 12 Winder-Rhodes (10.1016/j.neuropharm.2012.07.009_bib46) 2010; 24 Farah (10.1016/j.neuropharm.2012.07.009_bib10) 2009; 203 Goff (10.1016/j.neuropharm.2012.07.009_bib12) 2002 Herbert (10.1016/j.neuropharm.2012.07.009_bib14) 1976; 49 Minzenberg (10.1016/j.neuropharm.2012.07.009_bib21) 2008; 33 Claridge (10.1016/j.neuropharm.2012.07.009_bib6) 2009; 49 Wechsler (10.1016/j.neuropharm.2012.07.009_bib45) 1981; 6 Blackwell (10.1016/j.neuropharm.2012.07.009_bib3) 2004; 17 Sahakian (10.1016/j.neuropharm.2012.07.009_bib35) 1992; 85 Lezak (10.1016/j.neuropharm.2012.07.009_bib16) 2004 CANTABeclipse (10.1016/j.neuropharm.2012.07.009_bib5) 2011 Müller (10.1016/j.neuropharm.2012.07.009_bib25) 2004; 177 Bond (10.1016/j.neuropharm.2012.07.009_bib4) 1974; 47 Noppe (10.1016/j.neuropharm.2012.07.009_bib27) 1996; 9 Makris (10.1016/j.neuropharm.2012.07.009_bib18) 2004; 42 Wallach (10.1016/j.neuropharm.2012.07.009_bib44) 1965 Witkin (10.1016/j.neuropharm.2012.07.009_bib47) 2002 Sahakian (10.1016/j.neuropharm.2012.07.009_bib34) 2011; 25 Aron (10.1016/j.neuropharm.2012.07.009_bib1) 2003; 54 Robbins (10.1016/j.neuropharm.2012.07.009_bib33) 1998; 4 Turner (10.1016/j.neuropharm.2012.07.009_bib41) 2003; 165 de Rover (10.1016/j.neuropharm.2012.07.009_bib8) 2011; 49 Minzenberg (10.1016/j.neuropharm.2012.07.009_bib22) 2008; 322 Nelson (10.1016/j.neuropharm.2012.07.009_bib26) 1991 Gough (10.1016/j.neuropharm.2012.07.009_bib13) 1979; 37 Mehta (10.1016/j.neuropharm.2012.07.009_bib20) 1999; 146 Turner (10.1016/j.neuropharm.2012.07.009_bib42) 2004; 29 Repantis (10.1016/j.neuropharm.2012.07.009_bib32) 2010; 62 Morgan (10.1016/j.neuropharm.2012.07.009_bib24) 2010; 167 Stoops (10.1016/j.neuropharm.2012.07.009_bib39) 2005; 182 Martínez-Raga (10.1016/j.neuropharm.2012.07.009_bib19) 2008; 1 10.1016/j.neuropharm.2012.07.009_bib37 Czeisler (10.1016/j.neuropharm.2012.07.009_bib7) 2005; 353 Benerjee (10.1016/j.neuropharm.2012.07.009_bib2) 2004; 8 Scoriels (10.1016/j.neuropharm.2012.07.009_bib36) 2012; 220 Finke (10.1016/j.neuropharm.2012.07.009_bib11) 2010; 210 Wong (10.1016/j.neuropharm.2012.07.009_bib48) 1998; 38 Simon (10.1016/j.neuropharm.2012.07.009_bib38) 1994; 114 Randall (10.1016/j.neuropharm.2012.07.009_bib31) 2005; 82 Owen (10.1016/j.neuropharm.2012.07.009_bib29) 1995; 33 Provigil (10.1016/j.neuropharm.2012.07.009_bib30) 1997 Mohamed (10.1016/j.neuropharm.2012.07.009_bib23) 2012; 15 |
References_xml | – year: 1965 ident: bib44 article-title: Modes of Thinking in Young Children: a Study of the Creativity-intelligence Distinction contributor: fullname: Kogan – volume: 203 start-page: 541 year: 2009 end-page: 547 ident: bib10 article-title: When we can enhance cognition with Adderall, do we sacrifice creativity? publication-title: Psychopharmacology contributor: fullname: Chatterjee – volume: 37 start-page: 1398 year: 1979 end-page: 1405 ident: bib13 article-title: A creative personality scale for the adjective check list publication-title: J. Personality Soc. Psychol. contributor: fullname: Gough – volume: 17 start-page: 42 year: 2004 end-page: 48 ident: bib3 article-title: Detecting dementia: novel neuropsychological markers of preclinical Alzheimer's disease publication-title: Demen. Geriat. Cogn. Dis. contributor: fullname: Hodges – volume: 49 start-page: 2060 year: 2011 end-page: 2070 ident: bib8 article-title: Hippocampal dysfunction in patients with mild cognitive impairment: a functional neuroimaging study of a visuospatial paired associates learning task publication-title: Neuropsychologia contributor: fullname: Sahakian – volume: 33 start-page: 1477 year: 2008 end-page: 1502 ident: bib21 article-title: Modafinil: a review of neurochemical action and effects on cognition publication-title: Neuropsychopharmacology contributor: fullname: Carter – year: 1997 ident: bib30 article-title: Modafinil Data Sheet. Data for the First Authorisation contributor: fullname: Provigil – volume: 53 start-page: 52 year: 2009 end-page: 59 ident: bib15 article-title: Hemodynamic and cardiac neurotransmitter-releasing effects in conscious dogs of attention- and wake-promoting agents: a comparison of d-amphetamine, atomoxetine, modafinil, and a novel quinazolinone H3 inverse agonist publication-title: J. Cardiovasc. Pharmacol. contributor: fullname: Renger – volume: 182 start-page: 186 year: 2005 end-page: 193 ident: bib39 article-title: Reinforcing effects of modafinil: influence of dose and behavioral demands following drug administration publication-title: Psychopharmacology contributor: fullname: Rush – volume: 24 start-page: 1649 year: 2010 end-page: 1657 ident: bib46 article-title: Effects of modafinil and prazosin on cognitive and physiological functions in healthy volunteers publication-title: J. Psychopharmacol. contributor: fullname: Müller – volume: 8 start-page: 339 year: 2004 end-page: 354 ident: bib2 article-title: Psychopharmacology for excessive daytime sleepiness publication-title: Sleep Med. Rev. contributor: fullname: Grunsteinc – volume: 167 start-page: 331 year: 2010 end-page: 340 ident: bib24 article-title: Normalizing effects of modafinil on sleep in chronic cocaine users publication-title: Am. J. Psychiatry contributor: fullname: Malison – volume: 210 start-page: 317 year: 2010 end-page: 329 ident: bib11 article-title: Effects of modafinil and methylphenidate on visual attention capacity: a TVA-based study publication-title: Psychopharmacology contributor: fullname: Müller – volume: 1 start-page: 213 year: 2008 end-page: 221 ident: bib19 article-title: Modafinil: a useful medication for cocaine addiction? Review of the evidence from neuropharmacological, experimental and clinical studies publication-title: Curr. Drug Abuse Rev. contributor: fullname: Cepeda – volume: 62 start-page: 187 year: 2010 end-page: 206 ident: bib32 article-title: Modafinil and methylphenidate for neuroenhancement in healthy individuals: a systematic review publication-title: Pharmacol. Res. contributor: fullname: Heuser – volume: 42 start-page: 185 year: 2004 end-page: 195 ident: bib18 article-title: Wakepromoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity publication-title: Appetite contributor: fullname: Kelly – volume: 177 start-page: 161 year: 2004 end-page: 169 ident: bib25 article-title: Effects of modafinil on working memory processes in humans publication-title: Psychopharmacology contributor: fullname: Bublak – volume: 54 start-page: 1465 year: 2003 end-page: 1468 ident: bib1 article-title: Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder publication-title: Biol. Psychiatry contributor: fullname: Robbins – volume: 82 start-page: 133 year: 2005 end-page: 139 ident: bib31 article-title: Cognitive effects of modafinil in student volunteers may depend on IQ publication-title: Pharmacol. Biochem. Behav. contributor: fullname: File – volume: 4 start-page: 474 year: 1998 end-page: 490 ident: bib33 article-title: A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging publication-title: J. Int. Neuropsych. Soc. contributor: fullname: Rabbitt – volume: 47 start-page: 211 year: 1974 end-page: 218 ident: bib4 article-title: The use of analogue scales in rating subjective feelings publication-title: Br. J. Med. Psychol. contributor: fullname: Lader – year: 2002 ident: bib12 article-title: Abbreviated Torrance Test for Adults Manual contributor: fullname: Goff – volume: 38 start-page: 276 year: 1998 end-page: 282 ident: bib48 article-title: Single-dose pharmacokinetics of modafinil and methylphenidate given alone in and in combination to healthy male volunteers publication-title: J. Clin. Pharmacol. contributor: fullname: Grebow – volume: 29 start-page: 1363 year: 2004 end-page: 1373 ident: bib42 article-title: Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia publication-title: Neuropsychopharmacology contributor: fullname: Sahakian – volume: 12 start-page: 265 year: 2001 end-page: 280 ident: bib40 article-title: Early detection and differential diagnosis of Alzheimer's disease and depression with neuropsychological tasks publication-title: Dement. Geriatr. Cogn. contributor: fullname: Sahakian – year: 2011 ident: bib5 article-title: Test Administration Guide contributor: fullname: CANTABeclipse – volume: 114 start-page: 597 year: 1994 end-page: 600 ident: bib38 article-title: The stimulant effect of modafinil on wakefulness is not associated with an increase in anxiety in mice: a comparison with dexamphetamine publication-title: Psychopharmacology contributor: fullname: Costentin – volume: 6 start-page: 82 year: 1981 end-page: 85 ident: bib45 article-title: The psychometric tradition: developing the Wechsler adult intelligence scale publication-title: Contemp. Educ. Psychol. contributor: fullname: Wechsler – volume: 220 start-page: 249 year: 2012 end-page: 258 ident: bib36 article-title: Effects of modafinil on cognitive functions in first episode psychosis publication-title: Psychopharmacology contributor: fullname: Jones – year: 2004 ident: bib16 article-title: Neuropsychological Assessment contributor: fullname: Loring – year: 1991 ident: bib26 article-title: National Adult Reading Test contributor: fullname: Willison – volume: 165 start-page: 260 year: 2003 end-page: 269 ident: bib41 article-title: Cognitive enhancing effects of modafinil in healthy volunteers publication-title: Psychopharmacology contributor: fullname: Sahakian – volume: 322 start-page: 1700 year: 2008 end-page: 1702 ident: bib22 article-title: Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI publication-title: Science contributor: fullname: Carter – volume: 28 start-page: 1021 year: 1990 end-page: 1034 ident: bib28 article-title: Planning and spatial working memory following frontal lobe lesions in man publication-title: Neuropsychologia contributor: fullname: Robbins – volume: 6 start-page: 455 year: 2006 end-page: 468 ident: bib43 article-title: A review of the use of modafinil for attention-deficit hyperactivity disorder publication-title: Expert Rev. Neurother. contributor: fullname: Turner – volume: 161 start-page: 387 year: 2002 end-page: 395 ident: bib9 article-title: Study of the addictive potential of modafinil in naive and cocaine-experienced rats publication-title: Psychopharmacology contributor: fullname: Piazza – volume: 85 start-page: 399 year: 1992 end-page: 402 ident: bib35 article-title: Computerized assessment in neuropsychiatry using CANTAB: discussion paper publication-title: J. Roy Soc. Med. contributor: fullname: Owen – volume: 49 start-page: 373 year: 1976 end-page: 379 ident: bib14 article-title: Factor analysis of analogue scales measuring subjective feelings before and after sleep publication-title: Br. J. Med. Psychol. contributor: fullname: Dore – year: 2002 ident: bib47 article-title: Group Embedded Figures Test Manual contributor: fullname: Raskin – volume: 15 start-page: 559 year: 2012 end-page: 571 ident: bib23 article-title: The ethics of elective psychopharmacology publication-title: Int. J. Neuropsychopharmacol. contributor: fullname: Sahakian – volume: 9 start-page: 369 year: 1996 end-page: 383 ident: bib27 article-title: Progression in the service of the ego, cognitive styles, and creative thinking publication-title: Creativity Res. J. contributor: fullname: Noppe – volume: 353 start-page: 476 year: 2005 end-page: 486 ident: bib7 article-title: Modafinil for excessive sleepiness associated with shift-work sleep disorder publication-title: N. Engl. J. Med. contributor: fullname: U.S. Modafinil in Shift Work Sleep Disorder Study Group – volume: 25 start-page: 197 year: 2011 end-page: 204 ident: bib34 article-title: Neuroethical issues in cognitive enhancement publication-title: J. Psychopharmacol. contributor: fullname: Morein-Zamir – volume: 33 start-page: 1 year: 1995 end-page: 24 ident: bib29 article-title: Visual spatial short term recognition working memory and learning after temporal lobe excision, frontal lobe excision or amygdalo-hippocampectomy in man publication-title: Neuropsychologia contributor: fullname: Robbins – volume: 202 start-page: 487 year: 2009 end-page: 495 ident: bib17 article-title: Modafinil improves rapid shifts of attention publication-title: Psychopharmacology contributor: fullname: Rusted – volume: 146 start-page: 162 year: 1999 end-page: 174 ident: bib20 article-title: Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson’s disease publication-title: Psychopharmacology contributor: fullname: Robbins – volume: 49 start-page: 794 year: 2009 end-page: 799 ident: bib6 article-title: An investigation into the relationship between convergent and divergent thinking, schizotypy, and autistic traits publication-title: Pers. Indiv. Differ. contributor: fullname: McDonald – volume: 1 start-page: 213 year: 2008 ident: 10.1016/j.neuropharm.2012.07.009_bib19 article-title: Modafinil: a useful medication for cocaine addiction? Review of the evidence from neuropharmacological, experimental and clinical studies publication-title: Curr. Drug Abuse Rev. doi: 10.2174/1874473710801020213 contributor: fullname: Martínez-Raga – volume: 202 start-page: 487 year: 2009 ident: 10.1016/j.neuropharm.2012.07.009_bib17 article-title: Modafinil improves rapid shifts of attention publication-title: Psychopharmacology doi: 10.1007/s00213-008-1395-1 contributor: fullname: Marchant – volume: 6 start-page: 82 year: 1981 ident: 10.1016/j.neuropharm.2012.07.009_bib45 article-title: The psychometric tradition: developing the Wechsler adult intelligence scale publication-title: Contemp. Educ. Psychol. doi: 10.1016/0361-476X(81)90035-7 contributor: fullname: Wechsler – volume: 82 start-page: 133 year: 2005 ident: 10.1016/j.neuropharm.2012.07.009_bib31 article-title: Cognitive effects of modafinil in student volunteers may depend on IQ publication-title: Pharmacol. Biochem. Behav. doi: 10.1016/j.pbb.2005.07.019 contributor: fullname: Randall – volume: 353 start-page: 476 year: 2005 ident: 10.1016/j.neuropharm.2012.07.009_bib7 article-title: Modafinil for excessive sleepiness associated with shift-work sleep disorder publication-title: N. Engl. J. Med. doi: 10.1056/NEJMoa041292 contributor: fullname: Czeisler – volume: 42 start-page: 185 year: 2004 ident: 10.1016/j.neuropharm.2012.07.009_bib18 article-title: Wakepromoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity publication-title: Appetite doi: 10.1016/j.appet.2003.11.003 contributor: fullname: Makris – volume: 53 start-page: 52 year: 2009 ident: 10.1016/j.neuropharm.2012.07.009_bib15 article-title: Hemodynamic and cardiac neurotransmitter-releasing effects in conscious dogs of attention- and wake-promoting agents: a comparison of d-amphetamine, atomoxetine, modafinil, and a novel quinazolinone H3 inverse agonist publication-title: J. Cardiovasc. Pharmacol. doi: 10.1097/FJC.0b013e318195a470 contributor: fullname: Lynch – year: 2002 ident: 10.1016/j.neuropharm.2012.07.009_bib12 contributor: fullname: Goff – volume: 49 start-page: 373 year: 1976 ident: 10.1016/j.neuropharm.2012.07.009_bib14 article-title: Factor analysis of analogue scales measuring subjective feelings before and after sleep publication-title: Br. J. Med. Psychol. doi: 10.1111/j.2044-8341.1976.tb02388.x contributor: fullname: Herbert – volume: 33 start-page: 1 year: 1995 ident: 10.1016/j.neuropharm.2012.07.009_bib29 article-title: Visual spatial short term recognition working memory and learning after temporal lobe excision, frontal lobe excision or amygdalo-hippocampectomy in man publication-title: Neuropsychologia doi: 10.1016/0028-3932(94)00098-A contributor: fullname: Owen – ident: 10.1016/j.neuropharm.2012.07.009_bib37 doi: 10.1016/j.neuropharm.2012.07.011 – volume: 203 start-page: 541 year: 2009 ident: 10.1016/j.neuropharm.2012.07.009_bib10 article-title: When we can enhance cognition with Adderall, do we sacrifice creativity? publication-title: Psychopharmacology doi: 10.1007/s00213-008-1369-3 contributor: fullname: Farah – volume: 6 start-page: 455 year: 2006 ident: 10.1016/j.neuropharm.2012.07.009_bib43 article-title: A review of the use of modafinil for attention-deficit hyperactivity disorder publication-title: Expert Rev. Neurother. doi: 10.1586/14737175.6.4.455 contributor: fullname: Turner – year: 2004 ident: 10.1016/j.neuropharm.2012.07.009_bib16 contributor: fullname: Lezak – volume: 49 start-page: 2060 year: 2011 ident: 10.1016/j.neuropharm.2012.07.009_bib8 article-title: Hippocampal dysfunction in patients with mild cognitive impairment: a functional neuroimaging study of a visuospatial paired associates learning task publication-title: Neuropsychologia doi: 10.1016/j.neuropsychologia.2011.03.037 contributor: fullname: de Rover – volume: 37 start-page: 1398 year: 1979 ident: 10.1016/j.neuropharm.2012.07.009_bib13 article-title: A creative personality scale for the adjective check list publication-title: J. Personality Soc. Psychol. doi: 10.1037/0022-3514.37.8.1398 contributor: fullname: Gough – volume: 8 start-page: 339 year: 2004 ident: 10.1016/j.neuropharm.2012.07.009_bib2 article-title: Psychopharmacology for excessive daytime sleepiness publication-title: Sleep Med. Rev. doi: 10.1016/j.smrv.2004.03.002 contributor: fullname: Benerjee – volume: 146 start-page: 162 year: 1999 ident: 10.1016/j.neuropharm.2012.07.009_bib20 article-title: Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson’s disease publication-title: Psychopharmacology doi: 10.1007/s002130051102 contributor: fullname: Mehta – volume: 167 start-page: 331 year: 2010 ident: 10.1016/j.neuropharm.2012.07.009_bib24 article-title: Normalizing effects of modafinil on sleep in chronic cocaine users publication-title: Am. J. Psychiatry doi: 10.1176/appi.ajp.2009.09050613 contributor: fullname: Morgan – volume: 25 start-page: 197 year: 2011 ident: 10.1016/j.neuropharm.2012.07.009_bib34 article-title: Neuroethical issues in cognitive enhancement publication-title: J. Psychopharmacol. doi: 10.1177/0269881109106926 contributor: fullname: Sahakian – volume: 182 start-page: 186 year: 2005 ident: 10.1016/j.neuropharm.2012.07.009_bib39 article-title: Reinforcing effects of modafinil: influence of dose and behavioral demands following drug administration publication-title: Psychopharmacology doi: 10.1007/s00213-005-0044-1 contributor: fullname: Stoops – volume: 12 start-page: 265 year: 2001 ident: 10.1016/j.neuropharm.2012.07.009_bib40 article-title: Early detection and differential diagnosis of Alzheimer's disease and depression with neuropsychological tasks publication-title: Dement. Geriatr. Cogn. doi: 10.1159/000051269 contributor: fullname: Swainson – volume: 17 start-page: 42 year: 2004 ident: 10.1016/j.neuropharm.2012.07.009_bib3 article-title: Detecting dementia: novel neuropsychological markers of preclinical Alzheimer's disease publication-title: Demen. Geriat. Cogn. Dis. doi: 10.1159/000074081 contributor: fullname: Blackwell – year: 1997 ident: 10.1016/j.neuropharm.2012.07.009_bib30 contributor: fullname: Provigil – volume: 62 start-page: 187 year: 2010 ident: 10.1016/j.neuropharm.2012.07.009_bib32 article-title: Modafinil and methylphenidate for neuroenhancement in healthy individuals: a systematic review publication-title: Pharmacol. Res. doi: 10.1016/j.phrs.2010.04.002 contributor: fullname: Repantis – year: 2002 ident: 10.1016/j.neuropharm.2012.07.009_bib47 contributor: fullname: Witkin – volume: 177 start-page: 161 year: 2004 ident: 10.1016/j.neuropharm.2012.07.009_bib25 article-title: Effects of modafinil on working memory processes in humans publication-title: Psychopharmacology doi: 10.1007/s00213-004-1926-3 contributor: fullname: Müller – volume: 210 start-page: 317 year: 2010 ident: 10.1016/j.neuropharm.2012.07.009_bib11 article-title: Effects of modafinil and methylphenidate on visual attention capacity: a TVA-based study publication-title: Psychopharmacology doi: 10.1007/s00213-010-1823-x contributor: fullname: Finke – year: 2011 ident: 10.1016/j.neuropharm.2012.07.009_bib5 contributor: fullname: CANTABeclipse – volume: 161 start-page: 387 year: 2002 ident: 10.1016/j.neuropharm.2012.07.009_bib9 article-title: Study of the addictive potential of modafinil in naive and cocaine-experienced rats publication-title: Psychopharmacology doi: 10.1007/s00213-002-1080-8 contributor: fullname: Deroche-Gamonet – volume: 114 start-page: 597 year: 1994 ident: 10.1016/j.neuropharm.2012.07.009_bib38 article-title: The stimulant effect of modafinil on wakefulness is not associated with an increase in anxiety in mice: a comparison with dexamphetamine publication-title: Psychopharmacology doi: 10.1007/BF02244990 contributor: fullname: Simon – volume: 29 start-page: 1363 year: 2004 ident: 10.1016/j.neuropharm.2012.07.009_bib42 article-title: Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300457 contributor: fullname: Turner – volume: 49 start-page: 794 year: 2009 ident: 10.1016/j.neuropharm.2012.07.009_bib6 article-title: An investigation into the relationship between convergent and divergent thinking, schizotypy, and autistic traits publication-title: Pers. Indiv. Differ. doi: 10.1016/j.paid.2009.01.018 contributor: fullname: Claridge – volume: 220 start-page: 249 issue: 2 year: 2012 ident: 10.1016/j.neuropharm.2012.07.009_bib36 article-title: Effects of modafinil on cognitive functions in first episode psychosis publication-title: Psychopharmacology doi: 10.1007/s00213-011-2472-4 contributor: fullname: Scoriels – volume: 38 start-page: 276 year: 1998 ident: 10.1016/j.neuropharm.2012.07.009_bib48 article-title: Single-dose pharmacokinetics of modafinil and methylphenidate given alone in and in combination to healthy male volunteers publication-title: J. Clin. Pharmacol. doi: 10.1002/j.1552-4604.1998.tb04425.x contributor: fullname: Wong – volume: 322 start-page: 1700 year: 2008 ident: 10.1016/j.neuropharm.2012.07.009_bib22 article-title: Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI publication-title: Science doi: 10.1126/science.1164908 contributor: fullname: Minzenberg – volume: 33 start-page: 1477 year: 2008 ident: 10.1016/j.neuropharm.2012.07.009_bib21 article-title: Modafinil: a review of neurochemical action and effects on cognition publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1301534 contributor: fullname: Minzenberg – volume: 24 start-page: 1649 year: 2010 ident: 10.1016/j.neuropharm.2012.07.009_bib46 article-title: Effects of modafinil and prazosin on cognitive and physiological functions in healthy volunteers publication-title: J. Psychopharmacol. doi: 10.1177/0269881109105899 contributor: fullname: Winder-Rhodes – volume: 9 start-page: 369 year: 1996 ident: 10.1016/j.neuropharm.2012.07.009_bib27 article-title: Progression in the service of the ego, cognitive styles, and creative thinking publication-title: Creativity Res. J. doi: 10.1207/s15326934crj0904_8 contributor: fullname: Noppe – volume: 54 start-page: 1465 year: 2003 ident: 10.1016/j.neuropharm.2012.07.009_bib1 article-title: Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder publication-title: Biol. Psychiatry doi: 10.1016/S0006-3223(03)00609-7 contributor: fullname: Aron – volume: 15 start-page: 559 year: 2012 ident: 10.1016/j.neuropharm.2012.07.009_bib23 article-title: The ethics of elective psychopharmacology publication-title: Int. J. Neuropsychopharmacol. doi: 10.1017/S146114571100037X contributor: fullname: Mohamed – volume: 4 start-page: 474 year: 1998 ident: 10.1016/j.neuropharm.2012.07.009_bib33 article-title: A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging publication-title: J. Int. Neuropsych. Soc. doi: 10.1017/S1355617798455073 contributor: fullname: Robbins – volume: 85 start-page: 399 year: 1992 ident: 10.1016/j.neuropharm.2012.07.009_bib35 article-title: Computerized assessment in neuropsychiatry using CANTAB: discussion paper publication-title: J. Roy Soc. Med. contributor: fullname: Sahakian – volume: 47 start-page: 211 year: 1974 ident: 10.1016/j.neuropharm.2012.07.009_bib4 article-title: The use of analogue scales in rating subjective feelings publication-title: Br. J. Med. Psychol. doi: 10.1111/j.2044-8341.1974.tb02285.x contributor: fullname: Bond – year: 1991 ident: 10.1016/j.neuropharm.2012.07.009_bib26 contributor: fullname: Nelson – volume: 28 start-page: 1021 year: 1990 ident: 10.1016/j.neuropharm.2012.07.009_bib28 article-title: Planning and spatial working memory following frontal lobe lesions in man publication-title: Neuropsychologia doi: 10.1016/0028-3932(90)90137-D contributor: fullname: Owen – volume: 165 start-page: 260 year: 2003 ident: 10.1016/j.neuropharm.2012.07.009_bib41 article-title: Cognitive enhancing effects of modafinil in healthy volunteers publication-title: Psychopharmacology doi: 10.1007/s00213-002-1250-8 contributor: fullname: Turner – year: 1965 ident: 10.1016/j.neuropharm.2012.07.009_bib44 contributor: fullname: Wallach |
SSID | ssj0004818 |
Score | 2.447232 |
Snippet | Modafinil, a putative cognitive enhancing drug, has previously been shown to improve performance of healthy volunteers as well as patients with attention... ► Subjective ratings of task performance enjoyment were greater under modafinil. ► Modafinil enhanced performance on cognitive tests of planning and working... |
SourceID | pubmedcentral crossref pubmed elsevier |
SourceType | Open Access Repository Aggregation Database Index Database Publisher |
StartPage | 490 |
SubjectTerms | Adult Benzhydryl Compounds - adverse effects Benzhydryl Compounds - pharmacology Cognition - drug effects Cognitive enhancer Creative thinking Creativity Double-Blind Method Executive Function - drug effects Executive functions Female Humans Male Memory Memory, Short-Term - drug effects Modafinil Motivation Motivation - drug effects Nootropic Agents - adverse effects Nootropic Agents - pharmacology Pattern Recognition, Visual - drug effects Performance-Enhancing Substances - adverse effects Performance-Enhancing Substances - pharmacology Pleasure - drug effects Problem Solving - drug effects Spatial Behavior - drug effects Task Performance and Analysis Thinking - drug effects Young Adult |
Title | Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers |
URI | https://dx.doi.org/10.1016/j.neuropharm.2012.07.009 https://www.ncbi.nlm.nih.gov/pubmed/22820554 https://pubmed.ncbi.nlm.nih.gov/PMC3485563 |
Volume | 64 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1NT9wwELUQXHpBLaVlaUFzqPa0KUnsJI44rRBoW6QVB5C4Rfba0YYPZ9VNkfbCb-9MnLDsCaRe7cRxPKN5E-fNM2M_ZGYzy8NZkNrEBkLxKNBlqQMqdDTRLFPYR2yLaTq5Eb9vk9stdtbXwhCtsov9Pqa30bprOelW82RRVVTji9CYI6TFrW4dFfEJBCP06Z_Pa5qHkJHslZjp6o7N4zlerWbkgjSiieQVtzKeRE18A6I26ZOv8OjiI9vtEkkY-7l-YlvW7bHhlVeiXo3gel1YtRzBEK7WGtWrz2zuVYuXUJfwWBtVVq56gNqBq12A3q1x6I5ZVLsRNGp5D9bd1SvaTATlDPhs88lCM_fHL0DlwFdVroBiHloMU8t9dnNxfn02CbpDF4KZyPImMImWCanCmdTGUkvLpZ1JlUsTSpuXIklKTOFUFPKktLoMtZaRNUYpmeZGSM2_sG2cqj1gkHJt8F0EjzMcm4dahkYIlRls5YidAxb161wsvLZG0ZPO7oq1bQqyTRHSj_J8wE57gxQbflIgBLzj7q_edC_Pi_GTM8SUasCyDaO-XEDy25s9rpq3MtycdHVSfvhfM_rGPsTtARu0qfOdbTd__tojTHMafdz68THbGf-6nEz_AfMUA1g |
link.rule.ids | 230,315,786,790,891,4521,24144,27957,27958,45620,45714 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Nb9swDCW69NBdhq1bt2ztysPQU4zalmzL6KkoWqRfQQ8p0JshRTLibpODxSuQf1_KspvltAG7SpYsiwRJS4-PAN9EZjLDwlmQmsQEXLIoUGWpApfoqKNZJqnPoS0m6fieXz0kD1tw1ufCOFhlZ_u9TW-tdddy3O3m8aKqXI4vucacXFrc8tblr2CbJ1nEB7B9enk9nqzTI0UkejJmN6AD9HiYV0sbuXA00Q7nFbdMng6d-BcvtYmg_MMlXbyFN10siad-ue9gy9hdOLrzZNSrEU7XuVXLER7h3ZqmevUe5p64eIl1iT9rLcvKVj-wtmhrG5CCK5q6AxfVdoSNXH5HYx_rlTtPRGk1-oDzyWAz9xUYsLLoEytX6MweCY2iyw9wf3E-PRsHXd2FYMazvAl0okTiiOF0amKhhGHCzITMhQ6FyUueJCVFcTIKWVIaVYZKichoLaVIc82FYnswoKWaT4ApU5q-hbM4o7lZqESoOZeZplZG7nMIUb_PxcLTaxQ97uyxWMumcLIpQndXng_hpBdIsaEqBXmBfxj90Yvu5X0x_XWGFFUNIdsQ6ssDjoF7s8dW85aJmzlqnZR9_q8VHcLOeHp7U9xcTq6_wOu4rbfhznj2YdD8-m0OKOpp1NdOq58Bzt8GDg |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effects+of+modafinil+on+non-verbal+cognition%2C+task+enjoyment+and+creative+thinking+in+healthy+volunteers&rft.jtitle=Neuropharmacology&rft.au=M%C3%BCller%2C+U&rft.au=Rowe%2C+J+B&rft.au=Rittman%2C+T&rft.au=Lewis%2C+C&rft.date=2013-01-01&rft.eissn=1873-7064&rft.volume=64&rft.spage=490&rft_id=info:doi/10.1016%2Fj.neuropharm.2012.07.009&rft_id=info%3Apmid%2F22820554&rft.externalDocID=22820554 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0028-3908&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0028-3908&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0028-3908&client=summon |