Evaluation of the VE1 Antibody in Thyroid Cytology Using Ex Vivo Papillary Thyroid Carcinoma Specimens

• Published in: Journal of pathology and translational medicine Vol. 50; no. 1; pp. 58 - 66
• Main Authors: Kim, Yon Hee, Yim, Hyunee, Lee, Yong-Hee, Han, Jae Ho, Lee, Kyi Beom, Lee, Jeonghun, Soh, Euy Young, Jeong, Seon-Yong, Kim, Jang-Hee
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Society of Pathologists, Korean Society for Cytopathology 01.01.2016; The Korean Society of Pathologists and the Korean Society for Cytopathology; 대한병리학회
• Subjects: Cellular biology; Deoxyribonucleic acid; DNA; Immunoglobulins; Kinases; Melanoma; Mutation; Original; Proteins; Skin cancer; Thyroid cancer; 병리학; Immunohistochemistry; Thyroid gland; Biopsy, fine-needle; Cytology; BRAF mutation

Recently, VE1, a monoclonal antibody against the BRAFV600E mutant protein, has been investigated in terms of its detection of the BRAFV600E mutation. Although VE1 immunostaining and molecular methods used to assess papillary thyroid carcinoma in surgical specimens are in good agreement, evaluation o...