Clinical presentation of celiac disease in the pediatric population

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 128; no. 4 Suppl 1; p. S68
• Main Author: Fasano, Alessio
• Format: Journal Article
• Language: English
• Published: United States 01.04.2005
• Subjects: Adolescent; Age of Onset; Anorexia - etiology; Autoimmune Diseases; Celiac Disease - complications; Celiac Disease - diagnosis; Celiac Disease - pathology; Child; Child Development; Child, Preschool; Diarrhea - etiology; Female; Genetic Predisposition to Disease; Glutens - metabolism; Humans; Infant; Infant, Newborn; Male; Risk Factors; Severity of Illness Index

Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten-containing grains (including wheat, rye, and barley) in genetically susceptible individuals. CD is associated with HLA molecules DQ2 (90%-95%) and DQ8 (5%-10%), and in the continued presence of gluten the dise...