LncRNA OIP5-AS1/miR-410-3p/Wnt7b axis promotes the proliferation of rheumatoid arthritis fibroblast-like synoviocytes via regulating the Wnt/β-catenin pathway

• Published in: Autoimmunity (Chur, Switzerland) Vol. 56; no. 1; p. 2189136
• Main Authors: Sun, Yuan, Jiang, Hui, Pan, LingYu, Han, YanQuan, Chen, Yan, Jiang, Yeke, Wang, Yongzhong
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 31.12.2023; Taylor & Francis Group
• Subjects: Animals; Arthritis, Rheumatoid - genetics; beta Catenin - genetics; beta Catenin - metabolism; Cell Proliferation - genetics; fibroblast-like synoviocytes; Fibroblasts - metabolism; LncRNA OIP5-AS1; MicroRNAs - genetics; MicroRNAs - metabolism; proliferation; Rats; Rheumatoid arthritis; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Synoviocytes - metabolism; Wnt Signaling Pathway - genetics; Wnt/β-catenin pathway; LncRNA OIP5-AS1; fibroblast-like synoviocytes; Wnt/β-catenin pathway; proliferation; Rheumatoid arthritis

LncRNA OIP5-AS1 has a common gene imbalance in various cancers and tumours, which plays an important role in regulating its biological function. However, there are few studies on lncRNA OIP5-AS1 in rheumatoid arthritis (RA). The purpose of the present study was to investigate the role of lncRNA OIP5...