Transplantation of Adipose-Tissue-Engineered Constructs with CRISPR-Mediated UCP1 Activation - Michurina, Svetlana; Stafeev, Iurii; Boldyreva, Maria; Truong, Vu Anh; Ratner, Elizaveta; Menshikov, Mikhail; Hu, Yu-Chen; Parfyonova, Yelena (International journal of molecular sciences, 2023)
Keywords: Adipocytes; Adipocytes, Brown - metabolism; Adipose Tissue, Brown - transplantation; Adipose tissues; Analysis; Animals; Body fat; Cells; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR; Diabetes Mellitus, Type 2 - therapy; Efficiency; Energy consumption; Energy dissipation; Gene expression; Genes; Genetic engineering; Genomes; Glucose; Glucose - metabolism; Humans; Inflammation; Metabolism; Mice; Mice, Inbred C57BL; Morphology; Obesity; Scientific equipment and supplies industry; Technology application; Thermogenesis; Thermogenesis - genetics; Tissue engineering; Type 2 diabetes; Uncoupling Protein 1 - metabolism; United States; Massachusetts; Germany; Russia; CRISPR; thermogenesis; tissue engineering; adipocytes