Non-Targeted Metabolomics Approach Revealed Significant Changes in Metabolic Pathways in Patients with Chronic Traumatic Encephalopathy - Lee, Jinkyung; Kim, Suhyun; Kim, Yoon Hwan; Park, Uiyeol; Lee, Junghee; McKee, Ann C.; Kim, Kyoung Heon; Ryu, Hoon; Lee, Jeongae (Biomedicines, 2022)
Keywords: Acids; Alzheimer's disease; astrocyte activation; Autopsy; catecholamines; Chronic traumatic encephalopathy; chronic traumatic encephalopathy (CTE); Cognitive ability; Dementia; Discriminant analysis; Head injuries; High-performance liquid chromatography; Inflammation; Mass spectroscopy; Metabolic pathways; Metabolism; Metabolites; Metabolomics; Neurodegenerative diseases; non-targeted metabolomics; Patients; Phenylalanine; phenylalanine metabolism; Software; Solvents; Systems stability; Trauma; Traumatic brain injury; Tyrosine; tyrosine metabolism; United States--US; Germany