Survival in Children With Down Syndrome Undergoing Single-Ventricle Palliation

• Published in: The Annals of thoracic surgery Vol. 101; no. 5; pp. 1834 - 1841
• Main Authors: Colquitt, John L., MD, Morris, Shaine A., MD, MPH, Denfield, Susan W., MD, Fraser, Charles D., MD, Wang, Yunfei, PhD, Kyle, W. Buck, MD
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.05.2016
• Subjects: Airway Obstruction - etiology; Airway Obstruction - surgery; Cardiothoracic Surgery; Down Syndrome - mortality; Female; Heart Defects, Congenital - genetics; Heart Septal Defects - surgery; Heart Ventricles - abnormalities; Heart Ventricles - surgery; Humans; Hypertension, Pulmonary - drug therapy; Hypertension, Pulmonary - etiology; Infant; Kaplan-Meier Estimate; Male; Palliative Care; Postoperative Complications - mortality; Proportional Hazards Models; Retrospective Studies; Risk Factors; ROC Curve; Surgery; Survival Rate; Treatment Outcome; Vascular Resistance; Vasodilator Agents - therapeutic use

Background We describe survival in patients with Down syndrome (DS) with single-ventricle anatomy and palliation and characterize risk factors associated with mortality. Methods All patients with DS and single-ventricle anatomy documented in the electronic medical record at our institution from Janu...