Hydroxycitric acid reconstructs damaged articular cartilages by modifying the metabolic cascade in chondrogenic cells - Mizushina, Yoshiyuki; Sun, Liping; Nishio, Megumi; Nagata, Sanae; Kamakura, Takeshi; Fukuda, Masayuki; Tanaka, Kousuke; Toguchida, Junya; Jin, Yonghui (Osteoarthritis and cartilage open, 2025)
Keywords: ATP citrate lyase; Chondrogenesis; Hydroxycitric acid; Mitochondria; ORIGINAL PAPER; Osteoarthritis; β-catenin; ATP citrate lyase; DM-α-KG; OXPHOS; FCCP; WB; TMRE; FGF2; ActA; β-catenin; iPSCs; ACAN; LC-MS/MS; Mitochondria; OA; CPII; C2C; α-KG; FBS; Ac-CoA; Hydroxycitric acid; Chondrogenesis; RT-qPCR; Hyp; CP4H; PBS; 2D-CI; TSA; BM-MSCs; HCA; IP; 3D-CI; GAG; EDTA; ECAR; BMPs; ACLY; COL2A1; iMSCs; TGFβ; Osteoarthritis; HE; PN; dsDNA; OCR