Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias

• Published in: Parkinsonism & related disorders Vol. 47; pp. 50 - 56
• Main Authors: Hinkle, Jared T., Perepezko, Kate, Rosenthal, Liana S., Mills, Kelly A., Pantelyat, Alexander, Mari, Zoltan, Tochen, Laura, Bang, Jee Yun, Gudavalli, Medha, Yoritomo, Nadine, Butala, Ankur, Bakker, Catherine C., Johnson, Vanessa, Moukheiber, Emile, Dawson, Ted M., Pontone, Gregory M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2018
• Subjects: Adult; Aged; Aged, 80 and over; Biomarkers; Cognition Disorders - etiology; DDS; Depression; Disruptive, Impulse Control, and Conduct Disorders - diagnosis; Disruptive, Impulse Control, and Conduct Disorders - etiology; Dopamine Dysregulation Syndrome; Dyskinesias; Dyskinesias - diagnosis; Dyskinesias - etiology; Female; Hallucinations; Humans; ICD; Impulse control disorders; Logistic Models; Male; Middle Aged; Motor subtypes; Parkinson Disease - complications; Parkinson Disease - drug therapy; Parkinson Disease - psychology; Parkinson's disease; Psychiatric Status Rating Scales; Psychotic Disorders - diagnosis; Psychotic Disorders - etiology; Severity of Illness Index; Dyskinesias; DDS; Motor subtypes; Parkinson's disease; Impulse control disorders; Hallucinations; Depression; ICD; Dopamine Dysregulation Syndrome

Dopaminergic therapy in Parkinson's disease (PD) can be associated with both motoric (e.g., dyskinesias) and neuropsychiatric adverse effects. Examples of the latter include Dopamine Dysregulation Syndrome (DDS) and impulse control disorder (ICD), which are separate but related behavioral/psych...