Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE - Galeotti, Caroline; Stephen-Victor, Emmanuel; Karnam, Anupama; Das, Mrinmoy; Gilardin, Laurent; Maddur, Mohan S.; Wymann, Sandra; Vonarburg, Cédric; Chevailler, Alain; Dimitrov, Jordan D.; Benveniste, Olivier; Bruhns, Pierre; et al. (Journal of allergy and clinical immunology, 2019)
Keywords: Animal models; Animals; anti-IgE IgG; Anti-Inflammatory Agents - pharmacology; Antigens, CD - metabolism; Antigens, Differentiation, T-Lymphocyte - metabolism; antisynthetase syndrome; Autoimmune diseases; Basophils - drug effects; Basophils - immunology; Blocking antibodies; CD69 antigen; Cells, Cultured; Chromatography; Cytokines; dendritic cell immunoreceptor; dendritic cell–specific intercellular adhesion molecule 3–grabbing nonintegrin; dermatomyositis; Disease Models, Animal; Fc receptors; FcγRIIB; FcεRI; Flow cytometry; Granulocyte-macrophage colony-stimulating factor; Histamine; Histamine Release; Human subjects; Humans; Immunoglobulin E; Immunoglobulin E - metabolism; Immunoglobulin Fc Fragments - pharmacology; Immunoglobulin G; Immunoglobulins; Immunoglobulins, Intravenous - pharmacology; Inflammation; Inflammatory diseases; Interleukin 3; Interleukin 4; Interleukin 6; Interleukin 8; Interleukin-3 - metabolism; Intravenous administration; Lectins; Lectins, C-Type - metabolism; Leukocytes (basophilic); Lymphocytes T; Mice; Multiple myeloma; Myopathy; Phenotypes; Phosphorylation; polymyositis; Secretion; Signal transduction; Spleen; Syk Kinase - metabolism; Thymus; Up-Regulation; France; Germany; dendritic cell–specific intercellular adhesion molecule 3–grabbing nonintegrin; pSyk; Siglec; Syk; TSLP; antisynthetase syndrome; qRT-PCR; polymyositis; IVIG; dermatomyositis; SIGN-R1; anti-IgE IgG; FcγRIIB; dendritic cell immunoreceptor; FITC; APC; FcR; PE; DC-SIGN; DCIR; HSA; FcεRI; IL-33R; DC