Efficacy of levofloxacin as an antibacterial prophylaxis for acute leukemia patients receiving intensive chemotherapy: a systematic review and meta-analysis

• Published in: Hematology (Luxembourg) Vol. 24; no. 1; pp. 362 - 368
• Main Authors: Owattanapanich, Weerapat, Chayakulkeeree, Methee
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.01.2019
• Subjects: acute lymphoblastic leukemia; Acute myeloid leukemia; febrile; levofloxacin; neutropenia; prophylaxis; neutropenia; febrile; acute lymphoblastic leukemia; levofloxacin; Acute myeloid leukemia; prophylaxis

The incidence of febrile neutropenia (FN) in acute leukemia patients following induction or consolidation chemotherapy is high. Several clinical practice guidelines recommend the use of a fluoroquinolone prophylaxis to prevent bacterial infection in patients being prone to prolonged profound neutrop...