Comparative Study on Epidermal Moisturizing Effects and Hydration Mechanisms of Rice-Derived Glucosylceramides and Ceramides

• Published in: International Journal of Molecular Sciences Vol. 24; no. 1; p. 83
• Main Authors: Takeda, Shogo, Yoneda, Akari, Miyasaka, Kenchi, Manse, Yoshiaki, Morikawa, Toshio, Shimoda, Hiroshi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.12.2022; MDPI
• Subjects: Ceramides; Ceramides - metabolism; Epidermis; Epidermis - metabolism; Glucosylceramides; Glucosylceramides - metabolism; Humans; Oryza; Oryza - metabolism; rice bran oil; glucosylceramide; elasticamide; transepidermal water loss; stratum corneum; filaggrin; corneodesmosin; corneodesmosin; stratum corneum; transepidermal water loss; glucosylceramide; elasticamide; rice bran oil; filaggrin

Ceramide (Cer) plays an important role in skin barrier functions in the stratum corneum (SC). The ingestion of food-derived glucosylceramides (GlcCer) attenuates transepidermal water loss (TEWL). However, the moisturizing effects of single molecules of GlcCer and Cer remain unclear. Therefore, we he...