Oxytocin and Its Relationship to Body Composition, Bone Mineral Density, and Hip Geometry Across the Weight Spectrum

• Published in: The journal of clinical endocrinology and metabolism Vol. 102; no. 8; pp. 2814 - 2824
• Main Authors: Schorr, Melanie, Marengi, Dean A, Pulumo, Reitumetse L, Yu, Elaine, Eddy, Kamryn T, Klibanski, Anne, Miller, Karen K, Lawson, Elizabeth A
• Format: Journal Article
• Language: English
• Published: Washington, DC Endocrine Society 01.08.2017; Copyright Oxford University Press; Oxford University Press
• Subjects: Absorptiometry; Absorptiometry, Photon; Adult; Anorexia; Anorexia Nervosa - metabolism; Body Composition; Body Mass Index; Body weight; Bone composition; Bone Density; Bone mineral density; Clinical s; Cross-Sectional Studies; Dual energy X-ray absorptiometry; Eating disorders; Energy; Female; Geometry; Hip; Hip - diagnostic imaging; Hormones; Humans; Hypothalamus; Intra-Abdominal Fat - diagnostic imaging; Obesity; Obesity - metabolism; Osteoporosis; Overweight; Oxytocin; Oxytocin - metabolism; Spine; Spine - diagnostic imaging; Subcutaneous Fat - diagnostic imaging; Weight; Young Adult

ContextOxytocin (OXT), an anorexigenic hypothalamic hormone anabolic to bone, may reflect energy availability. Basal serum OXT levels are lower in anorexia nervosa (AN, state of energy deficit) than healthy controls (HC) and negatively associated with spine bone mineral density (BMD). Reports are co...