Innate immune activation and depressive and anxious symptoms across the peripartum: An exploratory study

• Published in: Psychoneuroendocrinology Vol. 99; pp. 80 - 86
• Main Authors: Osborne, Lauren M., Yenokyan, Gayane, Fei, Kezhen, Kraus, Thomas, Moran, Thomas, Monk, Catherine, Sperling, Rhoda
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2019
• Subjects: Adult; Affect - physiology; Anxiety; Anxiety - immunology; Anxiety - physiopathology; Anxiety Disorders - immunology; Biomarkers - blood; Cytokine; Cytokines; Depression; Depression - immunology; Depression - physiopathology; Depression, Postpartum - immunology; Female; Humans; Immunity; Immunity, Innate - immunology; Immunity, Innate - physiology; Inflammation; Longitudinal Studies; Peripartum Period - immunology; Peripartum Period - psychology; Pregnancy; Pregnancy Trimester, Third - immunology; Pregnancy Trimester, Third - psychology; Psychiatric Status Rating Scales; Pregnancy; Depression; Anxiety; Inflammation; Immunity; Cytokine

•Recent evidence indicates complex associations between immune functioning and depression.•Perinatal evidence is sparse, and rarely includes anxiety, which is more prevalent than depression in pregnancy.•This study measured mood, anxiety, and 23 cytokines at 5 points in pregnancy and postpartum in 5...