Evolution of Influenza A Virus by Mutation and Re-Assortment

• Published in: International journal of molecular sciences Vol. 18; no. 8; p. 1650
• Main Authors: Shao, Wenhan, Li, Xinxin, Goraya, Mohsan, Wang, Song, Chen, Ji-Long
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 07.08.2017; MDPI
• Subjects: Animals; Evolution, Molecular; Genome, Viral; Genomes; Host-Pathogen Interactions; Humans; Influenza; Influenza A virus - classification; Influenza A virus - genetics; Influenza, Human - epidemiology; Influenza, Human - virology; Mutation; Orthomyxoviridae Infections - epidemiology; Orthomyxoviridae Infections - virology; Pathogens; Reassortant Viruses - genetics; Review; Virus Replication; Viruses; virus-host interaction; mutation; re-assortment; influenza A virus

Influenza A virus (IAV), a highly infectious respiratory pathogen, has continued to be a significant threat to global public health. To complete their life cycle, influenza viruses have evolved multiple strategies to interact with a host. A large number of studies have revealed that the evolution of...