Screening for Pancreatic Cancer

Neither extended surgery nor extended indication for surgery has improved survival in patients with pancreatic cancer. According to autopsy studies, presumably 90% are metastatic. The only cure is complete removal of the tumor at an early stage before it becomes a systemic disease or becomes invasiv...

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Bibliographic Details
Published inThe Surgical clinics of North America Vol. 95; no. 5; p. 1041
Main Authors Wada, Keita, Takaori, Kyoichi, Traverso, L William
Format Journal Article
LanguageEnglish
Published United States 01.10.2015
Subjects
Adenocarcinoma, Mucinous - diagnosis
Adenocarcinoma, Mucinous - surgery
Carcinoma, Pancreatic Ductal - diagnosis
Carcinoma, Pancreatic Ductal - surgery
Carcinoma, Papillary - diagnosis
Carcinoma, Papillary - surgery
Early Detection of Cancer - methods
Humans
Pancreatectomy
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - surgery
Risk Assessment
Risk Factors
Screening
Intraductal papillary mucinous neoplasm
Familial pancreatic cancer
Pancreatic intraepithelial neoplasia
Pancreatic cancer
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Summary:Neither extended surgery nor extended indication for surgery has improved survival in patients with pancreatic cancer. According to autopsy studies, presumably 90% are metastatic. The only cure is complete removal of the tumor at an early stage before it becomes a systemic disease or becomes invasive. Early detection and screening of individuals at risk is currently under way. This article reviews the evidence and methods for screening, either familial or sporadic. Indication for early-stage surgery and precursors are discussed. Surgeons should be familiar with screening because it may provide patients with a chance for cure by surgical resection.
ISSN:1558-3171
DOI:10.1016/j.suc.2015.05.010