Tissue engineering of retina through high resolution 3-dimensional inkjet bioprinting

• Published in: Biofabrication Vol. 12; no. 2; p. 025006
• Main Authors: Masaeli, Elahe, Forster, Valérie, Picaud, Serge, Karamali, Fereshte, Nasr-Esfahani, Mohammad Hossein, Marquette, Christophe
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 31.01.2020
• Subjects: Animals; Biochemistry; Biochemistry, Molecular Biology; Bioengineering; Biomaterials; Bioprinting - instrumentation; Bioprinting - methods; Biotechnology; Cell Proliferation; Humans; Life Sciences; Photoreceptor Cells - cytology; Photoreceptor Cells - metabolism; Printing, Three-Dimensional - instrumentation; Retina - cytology; Retina - metabolism; Retinal Pigment Epithelium - cytology; Rhodopsin - metabolism; Swine; Tissue Engineering - instrumentation; Tissue Engineering - methods; Tissue Scaffolds - chemistry; Vascular Endothelial Growth Factor A - metabolism

The mammalian retina contains multiple cellular layers, each carrying out a specific task. Such a controlled organization should be considered as a crucial factor for designing retinal therapies. The maintenance of retinal layered complexity through the use of scaffold-free techniques has recently e...