Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing

• Published in: International journal of molecular sciences Vol. 23; no. 2; p. 583
• Main Authors: Sadeghi, Hosna Mohammad, Adeli, Ida, Calina, Daniela, Docea, Anca Oana, Mousavi, Taraneh, Daniali, Marzieh, Nikfar, Shekoufeh, Tsatsakis, Aristidis, Abdollahi, Mohammad
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 06.01.2022; MDPI
• Subjects: Disease Management; Drug Repositioning; Epigenetics; Female; Hormones; Humans; Hyperandrogenism; Insulin Resistance; Kinases; Polycystic ovary syndrome; Polycystic Ovary Syndrome - drug therapy; Polycystic Ovary Syndrome - etiology; Polycystic Ovary Syndrome - metabolism; Review; United States > US; molecular mechanisms; hyperandrogenism; management; insulin resistance; repurposing drugs; polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is an endocrine-gynecology disorder affecting many women of childbearing age. Although a part of the involved mechanism in PCOS occurrence is discovered, the exact etiology and pathophysiology are not comprehensively understood yet. We searched PubMed for PCOS pathog...