The monoamine neurotransmitter disorders: an expanding range of neurological syndromes

• Published in: Lancet neurology Vol. 10; no. 8; pp. 721 - 733
• Main Authors: Kurian, Manju A, Dr, Gissen, Paul, PhD, Smith, Martin, PhD, Heales, Simon JR, Prof, Clayton, Peter T, Prof
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2011; Elsevier Limited
• Subjects: Animals; Basal ganglia; Biogenic Monoamines - metabolism; Biomarkers - metabolism; Biosynthesis; Central nervous system diseases; Cerebrospinal fluid; Cofactors; Dopamine; Dopamine transporter; Dystonia; Encephalopathy; Enzymes; Epilepsy; Epinephrine; Humans; Hypoxia; Metabolic disorders; Metabolism; Metabolites; monoamines; Movement disorders; Nervous System Diseases - diagnosis; Nervous System Diseases - metabolism; Neurological diseases; Neurological disorders; Neurology; Neurotransmitter Agents - metabolism; Neurotransmitters; Norepinephrine; Paralysis; Parkinson's disease; Physiology; Serotonin; Syndrome

Summary The monoamine neurotransmitter disorders consist of a rapidly expanding heterogeneous group of neurological syndromes characterised by primary and secondary defects in the biosynthesis degradation, or transport of dopamine, norepinephrine, epinephrine, and serotonin. Disease onset can occur...