Role of aetiology, diabetes, tobacco smoking and hypertension in hepatocellular carcinoma survival

• Published in: Digestive and liver disease Vol. 47; no. 11; pp. 950 - 956
• Main Authors: Raffetti, Elena, Portolani, Nazario, Molfino, Sarah, Baiocchi, Gian Luca, Limina, Rosa Maria, Caccamo, Giovanni, Lamera, Rossella, Donato, Francesco
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.11.2015
• Subjects: Aged; Alcoholism - epidemiology; Attributable risk; Carcinoma, Hepatocellular - etiology; Carcinoma, Hepatocellular - mortality; Clinical-pathologic features; Comorbidity; Diabetes Mellitus - epidemiology; Female; Gastroenterology and Hepatology; Hepatitis, Chronic - complications; Hepatitis, Viral, Human - complications; Humans; Hypertension - epidemiology; Italy - epidemiology; Kaplan-Meier Estimate; Liver Cirrhosis, Alcoholic - complications; Liver Neoplasms - etiology; Liver Neoplasms - mortality; Male; Middle Aged; Prognosis; Proportional Hazards Models; Retrospective Studies; Risk Factors; Smoking - epidemiology; Survival Rate; Italy; Attributable risk; Clinical-pathologic features; Prognosis

Abstract Background Aim of this study was to investigate the role of aetiology, diabetes, tobacco smoking and hypertension in the survival of patients with hepatocellular carcinoma. Methods A prospective cohort of 552 patients (81.5% males, mean age 64.4 years) first diagnosed with hepatocellular ca...