Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome - Mirzayans, Razmik; Andrais, Bonnie; Kumar, Piyush; Murray, David (International journal of molecular sciences, 2017)
Keywords: Antineoplastic Agents - chemistry; Antineoplastic Agents - therapeutic use; Antineoplastic Agents - toxicity; Apoptosis; Apoptosis - drug effects; Cell cycle; Cell Cycle Checkpoints - drug effects; Cellular Senescence - drug effects; Chemotherapy; Cyclin-Dependent Kinase Inhibitor p21 - genetics; Cyclin-Dependent Kinase Inhibitor p21 - metabolism; Deoxyribonucleic acid; DNA; DNA Damage - drug effects; HSP40 Heat-Shock Proteins - genetics; HSP40 Heat-Shock Proteins - metabolism; Humans; Membrane Proteins - genetics; Membrane Proteins - metabolism; Molecular Chaperones - genetics; Molecular Chaperones - metabolism; Neoplasms - drug therapy; Neoplasms - metabolism; Neoplasms - pathology; Review; Signal Transduction - drug effects; Tumor Suppressor Protein p53 - genetics; Tumor Suppressor Protein p53 - metabolism; mutational processes; multinucleated giant cells; chemical genotoxic agents; DNAJB9; apoptosis; p53 signaling; premature senescence; p21WAF1 (CDKN1A)