Sensing Cells-Peptide Hydrogel Interaction In Situ via Scanning Ion Conductance Microscopy

• Published in: Cells (Basel, Switzerland) Vol. 11; no. 24; p. 4137
• Main Authors: Tikhonova, Tatiana N., Kolmogorov, Vasilii S., Timoshenko, Roman V., Vaneev, Alexander N., Cohen-Gerassi, Dana, Osminkina, Liubov A., Gorelkin, Petr V., Erofeev, Alexander S., Sysoev, Nikolay N., Adler-Abramovich, Lihi, Shirshin, Evgeny A.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.12.2022; MDPI
• Subjects: Aqueous solutions; Biocompatibility; Biomedical materials; Cell adhesion; Cell culture; Cell migration; Cell physiology; cells; Composition; Conductance; Cytosol; fibrillation; Gels (Pharmacy); hydrogel; Hydrogels; Ions; Lasers; Methods; Microscope and microscopy; Microscopy; Microscopy, Fluorescence; peptide self-assembly; Peptides; pH effects; Physiological aspects; Regenerative medicine; Scanning; scanning ion conductance microscopy; Tissue engineering; Topography; Russia; United Kingdom > UK; United States > US; Berlin Germany; Germany; scanning ion conductance microscopy; cells; hydrogel; regenerative medicine; reactive oxygen species; peptide self-assembly; fibrillation

Peptide-based hydrogels were shown to serve as good matrices for 3D cell culture and to be applied in the field of regenerative medicine. The study of the cell-matrix interaction is important for the understanding of cell attachment, proliferation, and migration, as well as for the improvement of th...