Highly efficient NIR-II photothermal therapy amplified ROS oxide breast tumor therapy by mesoporous gallium-enriched platinum nanomedicine
Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal the...
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| Published in | Materials today bio Vol. 32; p. 101869 |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.06.2025
Elsevier |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating via mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG2000 (PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues via the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000–1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both in vitro and in vivo studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation.
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| AbstractList | Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating
via
mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG
2000
(PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues
via
the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000–1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both
in vitro
and
in vivo
studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation.
Image 1 Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating via mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG2000 (PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues via the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000–1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both in vitro and in vivo studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation. Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating via mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG2000 (PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues via the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000-1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both in vitro and in vivo studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation.Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating via mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG2000 (PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues via the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000-1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both in vitro and in vivo studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation. Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG (PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000-1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both and studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation. Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. In this work, in order solve the current bottleneck problems of photothermal therapy (PTT) with longer light excitation as well as synergistic eactive oxygen species (ROS) storm mediating via mental element catalyst without toxic side effects. We have proposed a one-step method to produce mesoporous PtGa bimetallic composition with surface modification of PEG2000 (PtGaP) for the first time. Specifically, it can effectively concentrate at tumor tissues via the mesoporous nanostructure. Owing to the strong absorption in NIR-II region (1000–1700 nm) from Pt and Fenton-like catalyst of Ga, the ROS storm is efficaciously mediated. Remarkably, under safer NIR-II (1064 nm) laser irradiation, both in vitro and in vivo studies confirm that our bimetallic mesoporous nanomedicine effectively prevents tumor growth through synergistic PTT and oxidative therapy (OXT). Given its high bio-safety performance, we can conclude that the PtGaP has strong biocompatibility and holds great prospect in clinic translation. [Display omitted] |
| ArticleNumber | 101869 |
| Author | Ying, Yunfei Wang, Ao Li, Tingting Su, Yonghui Liu, Xiaolong Zhang, Fuxing Li, Siyaqi Wang, Peiyuan Lin, Kecan Zhuang, Hongjun |
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| Cites_doi | 10.1002/1097-0142(19801101)46:9<2009::AID-CNCR2820460919>3.0.CO;2-A 10.1021/acsnano.3c06486 10.1016/j.carbpol.2022.120510 10.1002/anie.202404395 10.1200/JCO.22.01342 10.1038/nrc3495 10.1016/j.jcis.2024.02.160 10.1016/j.jcis.2024.08.154 10.1038/s41467-024-50557-w 10.1002/adhm.202201986 10.1002/adhm.202101607 10.1039/D5MH00003C 10.1016/j.jcis.2019.09.120 10.1016/j.apsb.2024.10.009 10.1002/adma.201701683 10.1039/C5NR04557F 10.3322/caac.21763 10.1021/acsami.3c09324 10.1021/acsnano.2c00732 10.1021/acs.accounts.4c00031 10.1002/adfm.202211846 10.1093/annonc/mdw092 10.1021/acsestengg.1c00323 10.1016/j.ccr.2024.215718 10.1002/1097-0142(197911)44:5<1722::AID-CNCR2820440528>3.0.CO;2-C 10.1016/j.biomaterials.2013.03.077 10.1007/978-1-0716-3786-9_16 10.1038/nphoton.2016.76 10.1016/j.jcis.2024.12.076 10.1002/adfm.202407317 10.1016/j.apt.2021.01.032 10.1002/adma.201904836 10.1126/science.1136726 10.1016/j.ceramint.2024.11.050 10.1016/j.ccr.2024.216056 10.1093/neuonc/noad179.0339 10.1016/j.jcis.2024.09.160 10.1016/j.jconrel.2023.11.005 10.1016/j.cej.2023.148270 10.1002/cpz1.531 10.1021/acsami.2c05992 10.1021/acsnano.1c10732 10.1038/nmat2930 10.1016/j.jcis.2023.02.041 10.1002/anie.201510031 10.1073/pnas.2203994119 10.1039/D3CS00926B 10.1063/5.0021647 10.1016/S0140-6736(20)32381-3 10.1038/nmat1983 10.1002/biof.1159 10.1016/j.carbpol.2024.121795 10.1002/cac2.12358 |
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| Keywords | PtGaP nanomedicine Mesoporous structure Tumor targeting NIR-II PTT Synergistic OXT |
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| References | Du, Li, Wu, Wang, Yang, Fan, Qiu, Yan, Wang, Zhao, Zhao, Chen (bib15) 2022; 14 Yu, Li, Yu, Yan, Xu, Yin (bib38) 2024; 518 Lin, Chen, Yu, Wang, Qiu, Li, Yin, Stang (bib40) 2022; 119 Younis, Wang, An, Wang, Younis, Li, Wang, Ihsan, Ye, Xia (bib34) 2019; 13 Lu, Song, Feng, Wang, Mao, Gao, Zhao, Wang (bib47) 2024; 481 Feldenzer, Sarno (bib22) 2018; 9 Wang, Zhang, Wang, Liu, Yang, Zhao, Peng (bib12) 2024; 329 Deng, Xian, Cai, Liao, Lei, Han, An, He, Quan, Wu, Peng, Lu, Zhang (bib19) 2023; 33 Wang, Wang, Yang, Jin, Wang, Yan, Wu, Gao, Lei, Zhu, Wang, Song, Zhang (bib61) 2019; 31 Xu, Li, Yin, Huang (bib36) 2024; 53 Mahner, Trillsch, Chi, Harter, Pfisterer, Hilpert, Burges, Weissenbacher, du Bois (bib6) 2016; 27 Xu, Zhang, Liu, Guo, Zhang, Cai, Li, Zhang, Guan, Yu, Zou, Xiao, Wu (bib17) 2025 Kang, Wang, Xin, Chen, Zhao, Yu, Song, Zheng, Dai, Zhang, Zhang (bib43) 2024; 13 Siegel, Miller, Wagle, Jemal (bib1) 2023; 73 Chen, Wang, Cui, Li, Lee (bib18) 2021; 10 Torti, Torti (bib21) 2013; 13 Loibl, Poortmans, Morrow, Denkert, Curigliano (bib7) 2021; 397 Truong, Hayles, Bright, Luu, Dickey, Kalantar-Zadeh, Vasilev (bib25) 2023; 17 Takano, Hayashi, Fukushima, Takizawa (bib56) 2021; 32 Lee, Gao, Chou, Wan, Hsu, Tan, Li, Guan, Chen, Li, Wong, Lee (bib14) 2024; 34 Cathcart-Rake, Tevaarwerk, Haddad, D'Andre, Ruddy (bib5) 2023; 382 Tiwari, Shukla, Yadav, Singh, Marwaha, Gautam, Bakshi, Rai, Kumar, Sharma, Mishra (bib10) 2024; 365 Manikandan, Hasan, Wu (bib53) 2013; 34 Yao, Qiu, Xing, Li, Zhang, Tu, Peng, Wu, Yang, Wu (bib20) 2024; 18 Zhang, Han, Xu, Foley, Zhang, Codrington, Gray, Sun (bib51) 2016; 10 Feng, Mao, Wang, Zhou, Lu, Zhao, Wang (bib59) 2020; 559 Wang, Zhou, Liu, Qiao, Han, Wang, Liu, Qiu, Zhang, Wang, Zhou, Zeng, Yu, Fu (bib48) 2024; 15 Zhu, Wang, Zhao, Zhou, Feng, Gai, Yang (bib52) 2022; 16 Hsieh, Frisch, Wilks, Bär (bib57) 2023; 15 Bonchi, Imperi, Minandri, Visca, Frangipani (bib23) 2014; 40 Li, Liu, Huo, Su, Wu, Lin, Ge, Mu, Zhang, Zheng, Song (bib54) 2022; 16 Lee, Khaja, Velasquez-Castano, Dasari, Sun, Petros, Taylor, Murthy (bib49) 2007; 6 Feng, Xiao, Lu, Chen, Jiang, Xu, Gu, Wang, Zhao (bib45) 2024; 663 Mao, Ma, Wang, Ye (bib16) 2025; 15 Li, Huang, Stang, Yin (bib37) 2024; 57 Li, Tian, Zhu, Jiang, He, Li, Luo, Sun, Liu, Wang (bib41) 2022; 11 Zhang, Xu, Wei, Wu, Zeng (bib50) 2025; 678 Chen, Zhang, Huang, Dong, Dai, Feng, Lin, Sun, Yang, Xie, Chen, Guo, Jing (bib9) 2023; 10 Carrageta, Brito, Oliveira, Alves (bib63) 2022; 2 Kelsen, Alcock, Yeh, Brown, Young (bib27) 1980; 46 Moghaddam, Heidari, Zare, Djatoubai, Paiva-Santos, Bertani, Wu (bib11) 2023; 304 Wittkämper, Maisel, Wu, Frisch, Wilks, Grabau, Spiecker, Bär, Görling, Steinrück, Papp (bib58) 2020; 153 Connelly, Zoss, Schmainda, Al-Gizawiy, Pinheiro, Chitambar (bib26) 2023; 25 Eid, Wang, He, Wang, Ahamad, Alshehri, Yamauchi, Wang (bib55) 2015; 7 Zhang, Bu, Ni, Zhang, Li, Yao, Zhang, Yao, Wang, Shi (bib32) 2016; 55 Xie, Huang, Wang, Guo, Lin, Lin, Du (bib2) 2025; 51 Shah, Dobrovoskaia (bib62) 2024; 2789 Krakoff, Newman, Goldberg (bib28) 1979; 44 Jayasekera, Zhao, Schechter, Lowry, Yeh, Schwartz, O'Neill, Wernli, Stout, Mandelblatt, Kurian, Isaacs (bib4) 2023; 41 Hong, Xu (bib3) 2022; 42 Demetriou, Launey, Garrett, Schramm, Hofmann, Johnson, Ritchie (bib31) 2011; 10 He, Ye, Zhang, Yao, Zhou (bib24) 2022; 34 Tang, Zhang, Liu, Ni, Zhang, Zhang, Yao, He, Shi, Bo (bib33) 2017; 29 Chowdhury, Ghosh, Samanta, Jaggi, Chauhan, Yallapu (bib8) 2021; 6 Yang, Xu, Gu, Nan, Chen, Wang, Zhang, Zhao (bib46) 2025; 683 Cheng, He, Lu, Yan, Song, Mao, Di, Gao, Zhao, Wang (bib60) 2023; 639 Xie, Qi, Li, Zhang, Li, Zhong, Tang, Zhou (bib29) 2021; 6 Liu, Wang, Wang, Zhao, Pan, Wang (bib30) 2007; 315 Wei, Wu, Zheng, Ouyang, Ma, Ji, Yin (bib44) 2024; 63 Wang, Zhang, Wang, Yu, Gao, Yang, Li, Wang, Li (bib13) 2024; 34 Hu, Zhou, Yang, Hall, Nie, Yao, Duan, Wang (bib35) 2022; 2 Meng, Wang, Wang, Tao, Anastassova, Sun, Sun, Wang (bib42) 2025 Li, Jiang, Yan, Ye, Li, Dehaen, Yin (bib39) 2024; 506 Lin (10.1016/j.mtbio.2025.101869_bib40) 2022; 119 Xie (10.1016/j.mtbio.2025.101869_bib29) 2021; 6 Zhu (10.1016/j.mtbio.2025.101869_bib52) 2022; 16 Yu (10.1016/j.mtbio.2025.101869_bib38) 2024; 518 Mahner (10.1016/j.mtbio.2025.101869_bib6) 2016; 27 Wang (10.1016/j.mtbio.2025.101869_bib48) 2024; 15 Chowdhury (10.1016/j.mtbio.2025.101869_bib8) 2021; 6 Demetriou (10.1016/j.mtbio.2025.101869_bib31) 2011; 10 Wang (10.1016/j.mtbio.2025.101869_bib12) 2024; 329 Kelsen (10.1016/j.mtbio.2025.101869_bib27) 1980; 46 Takano (10.1016/j.mtbio.2025.101869_bib56) 2021; 32 Chen (10.1016/j.mtbio.2025.101869_bib18) 2021; 10 Manikandan (10.1016/j.mtbio.2025.101869_bib53) 2013; 34 Siegel (10.1016/j.mtbio.2025.101869_bib1) 2023; 73 Hu (10.1016/j.mtbio.2025.101869_bib35) 2022; 2 Lee (10.1016/j.mtbio.2025.101869_bib49) 2007; 6 Krakoff (10.1016/j.mtbio.2025.101869_bib28) 1979; 44 Xu (10.1016/j.mtbio.2025.101869_bib36) 2024; 53 Chen (10.1016/j.mtbio.2025.101869_bib9) 2023; 10 Kang (10.1016/j.mtbio.2025.101869_bib43) 2024; 13 Wei (10.1016/j.mtbio.2025.101869_bib44) 2024; 63 Wittkämper (10.1016/j.mtbio.2025.101869_bib58) 2020; 153 Xu (10.1016/j.mtbio.2025.101869_bib17) 2025 Cathcart-Rake (10.1016/j.mtbio.2025.101869_bib5) 2023; 382 Tiwari (10.1016/j.mtbio.2025.101869_bib10) 2024; 365 Meng (10.1016/j.mtbio.2025.101869_bib42) 2025 Bonchi (10.1016/j.mtbio.2025.101869_bib23) 2014; 40 Li (10.1016/j.mtbio.2025.101869_bib37) 2024; 57 Li (10.1016/j.mtbio.2025.101869_bib41) 2022; 11 Wang (10.1016/j.mtbio.2025.101869_bib13) 2024; 34 Li (10.1016/j.mtbio.2025.101869_bib39) 2024; 506 Shah (10.1016/j.mtbio.2025.101869_bib62) 2024; 2789 Cheng (10.1016/j.mtbio.2025.101869_bib60) 2023; 639 Li (10.1016/j.mtbio.2025.101869_bib54) 2022; 16 Feng (10.1016/j.mtbio.2025.101869_bib59) 2020; 559 Wang (10.1016/j.mtbio.2025.101869_bib61) 2019; 31 Connelly (10.1016/j.mtbio.2025.101869_bib26) 2023; 25 Hsieh (10.1016/j.mtbio.2025.101869_bib57) 2023; 15 Lee (10.1016/j.mtbio.2025.101869_bib14) 2024; 34 Du (10.1016/j.mtbio.2025.101869_bib15) 2022; 14 Yao (10.1016/j.mtbio.2025.101869_bib20) 2024; 18 Xie (10.1016/j.mtbio.2025.101869_bib2) 2025; 51 Loibl (10.1016/j.mtbio.2025.101869_bib7) 2021; 397 Torti (10.1016/j.mtbio.2025.101869_bib21) 2013; 13 Truong (10.1016/j.mtbio.2025.101869_bib25) 2023; 17 Mao (10.1016/j.mtbio.2025.101869_bib16) 2025; 15 Liu (10.1016/j.mtbio.2025.101869_bib30) 2007; 315 Feldenzer (10.1016/j.mtbio.2025.101869_bib22) 2018; 9 Hong (10.1016/j.mtbio.2025.101869_bib3) 2022; 42 Feng (10.1016/j.mtbio.2025.101869_bib45) 2024; 663 Lu (10.1016/j.mtbio.2025.101869_bib47) 2024; 481 Moghaddam (10.1016/j.mtbio.2025.101869_bib11) 2023; 304 Deng (10.1016/j.mtbio.2025.101869_bib19) 2023; 33 Eid (10.1016/j.mtbio.2025.101869_bib55) 2015; 7 Jayasekera (10.1016/j.mtbio.2025.101869_bib4) 2023; 41 Zhang (10.1016/j.mtbio.2025.101869_bib51) 2016; 10 Yang (10.1016/j.mtbio.2025.101869_bib46) 2025; 683 Zhang (10.1016/j.mtbio.2025.101869_bib32) 2016; 55 Tang (10.1016/j.mtbio.2025.101869_bib33) 2017; 29 He (10.1016/j.mtbio.2025.101869_bib24) 2022; 34 Zhang (10.1016/j.mtbio.2025.101869_bib50) 2025; 678 Younis (10.1016/j.mtbio.2025.101869_bib34) 2019; 13 Carrageta (10.1016/j.mtbio.2025.101869_bib63) 2022; 2 |
| References_xml | – volume: 41 start-page: 859 year: 2023 end-page: 870 ident: bib4 article-title: Reassessing the benefits and harms of risk-reducing medication considering the persistent risk of breast cancer mortality in estrogen receptor-positive breast cancer publication-title: J. Clin. Oncol. – volume: 34 year: 2022 ident: bib24 article-title: Visualized gallium/lyticase-integrated antifungal strategy for fungal keratitis treatment publication-title: Adv. Mater. – volume: 25 start-page: 89 year: 2023 ident: bib26 article-title: CTNI-57. Preliminary results of a phase 1 trial of oral gallium maltolate in recurrent glioblastoma publication-title: Neuro Oncol. – volume: 13 start-page: 2544 year: 2019 end-page: 2557 ident: bib34 article-title: Low power single laser activated synergistic cancer phototherapy using photosensitizer functionalized dual plasmonic photothermal nanoagents publication-title: ACS Nano – volume: 34 year: 2024 ident: bib14 article-title: Construction of through‐space charge‐transfer nanoparticles for facilely realizing high‐performance NIR‐II cancer phototheranostics publication-title: Adv. Funct. Mater. – volume: 14 start-page: 36527 year: 2022 end-page: 36535 ident: bib15 article-title: In situ engineering of the Cu publication-title: ACS Appl. Mater. Interfaces – start-page: 796 year: 2025 end-page: 803 ident: bib42 article-title: Photothermal and enhanced chemodynamic reinforced anti-tumor therapy based on PDA@POM nanocomposites publication-title: J. Colloid Interface Sci. 678 Part C – volume: 639 start-page: 249 year: 2023 end-page: 262 ident: bib60 article-title: Degradable iron-rich mesoporous dopamine as a dual-glutathione depletion nanoplatform for photothermal-enhanced ferroptosis and chemodynamic therapy publication-title: J. Colloid Interface Sci. – volume: 329 year: 2024 ident: bib12 article-title: A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy publication-title: Carbohydr. Polym. – volume: 6 start-page: 3269 year: 2021 end-page: 3287 ident: bib8 article-title: mBioactive nanotherapeutic trends to combat triple negative breast cancer publication-title: Bioact. Mater. – volume: 10 year: 2023 ident: bib9 article-title: Single atom-doped nanosonosensitizers for mutually optimized sono/chemo-nanodynamic therapy of triple negative breast cancer publication-title: Adv. Sci. – volume: 32 start-page: 860 year: 2021 end-page: 865 ident: bib56 article-title: Room-temperature synthesis of γ-Ga publication-title: Adv. Powder Technol. – volume: 559 start-page: 51 year: 2020 end-page: 64 ident: bib59 article-title: Triple stimuli-responsive ZnO quantum dots-conjugated hollow mesoporous carbon nanoplatform for NIR-induced dual model antitumor therapy publication-title: J. Colloid Interface Sci. – volume: 51 start-page: 685 year: 2025 end-page: 692 ident: bib2 article-title: Pt loaded CoFe2O4-based nanoparticles for breast cancer treatment with chemodynamic therapy and sonodynamic therapy publication-title: Cerm. Int. – volume: 10 start-page: 123 year: 2011 end-page: 128 ident: bib31 article-title: A damage-tolerant glass publication-title: Nat. Mater. – volume: 27 start-page: i30 year: 2016 end-page: i32 ident: bib6 article-title: Neoadjuvant chemotherapy in ovarian cancer revisited publication-title: Ann. Oncol. – volume: 663 start-page: 577 year: 2024 end-page: 590 ident: bib45 article-title: Tumor microenvironment sensitization via dual-catalysis of carbon-based nanoenzyme for enhanced photodynamic therapy publication-title: J. Colloid Interface Sci. – volume: 9 start-page: 496 year: 2018 end-page: 504 ident: bib22 article-title: Hypercalcemia of malignancy publication-title: J. Adv. Pract. Oncol. – volume: 53 start-page: 3167 year: 2024 end-page: 3204 ident: bib36 article-title: Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications publication-title: Chem. Soc. Rev. – volume: 29 year: 2017 ident: bib33 article-title: Antiferromagnetic pyrite as the tumor microenvironment-mediated nanoplatform for self-enhanced tumor imaging and therapy publication-title: Adv. Mater. – volume: 683 start-page: 910 year: 2025 end-page: 925 ident: bib46 article-title: Oxidative stress-augmented Cu-doped hollow mesoporous carbon nanozyme for photothermal/photodynamic synergistic therapy publication-title: J. Colloid Interface Sci. – volume: 55 start-page: 2101 year: 2016 end-page: 2106 ident: bib32 article-title: Synthesis of iron nanometallic glasses and their application in cancer therapy by a localized Fenton reaction publication-title: Angew. Chem. Int. Ed. – volume: 42 start-page: 913 year: 2022 end-page: 936 ident: bib3 article-title: Breast cancer: an up-to-date review and future perspectives publication-title: Cancer Commun. – volume: 6 start-page: 3812 year: 2021 end-page: 3823 ident: bib29 article-title: Ultrasmall Ga-ICG nanoparticles based gallium ion/photodynamic synergistic therapy to eradicate biofilms and against drug-resistant bacterial liver abscess publication-title: Bioact. Mater. – volume: 7 year: 2015 ident: bib55 article-title: One-step synthesis of porous bimetallic PtCu nanocrystals with high electrocatalytic activity for methanol oxidation reaction publication-title: Nanoscale – volume: 44 start-page: 1722 year: 1979 end-page: 1727 ident: bib28 article-title: Clinical toxicologic and pharmacologic studies of gallium nitrate publication-title: Cancer – volume: 481 year: 2024 ident: bib47 article-title: Nanozyme-mediated biocatalysis as a mitochondrial oxidative stress amplifier for tumor nanocatalytic immunotherapy publication-title: Chem. Eng. J. – volume: 15 start-page: 657 year: 2025 end-page: 660 ident: bib16 article-title: Microglial APOE4 promotes neuron degeneration in Alzheimer's disease through inhibition of lipid droplet autophagy publication-title: Acta Pharm. Sin. B – volume: 506 year: 2024 ident: bib39 article-title: Near-infrared boron–dipyrrin (BODIPY) nanomaterials: molecular design and anti-tumor therapeutics publication-title: Coord. Chem. Rev. – year: 2025 ident: bib17 article-title: Reducing exciton binding energy of antimony-based perovskites by improving the phase purity for efficient solar cells publication-title: Mater. Horiz. – volume: 518 year: 2024 ident: bib38 article-title: Biomarker-activatable photosensitizers with aggregation-induced emission characteristics for photodynamic therapy publication-title: Coord. Chem. Rev. – volume: 73 start-page: 17 year: 2023 end-page: 48 ident: bib1 article-title: Cancer statistics publication-title: Ca - Cancer J. Clin. – volume: 382 year: 2023 ident: bib5 article-title: Advances in the care of breast cancer survivors publication-title: BMJ Br. Med. J. (Clin. Res. Ed.) – volume: 13 year: 2024 ident: bib43 article-title: Biodegradable cascade-amplified nanotheranostics for photoacoustic-guided synergistic PTT/CDT/starvation antitumor in the NIR-II window publication-title: Adv. Healthcare Mater. – volume: 2789 start-page: 153 year: 2024 end-page: 159 ident: bib62 article-title: Detection of nanoparticle-mediated change in mitochondrial membrane potential in T cells using JC-1 dye publication-title: Methods Mol. Biol. – volume: 153 year: 2020 ident: bib58 article-title: Oxidation induced restructuring of Rh-Ga SCALMS model catalyst systems publication-title: J. Chem. Phys. – volume: 34 year: 2024 ident: bib13 article-title: A NIR‐II‐emissive organic nanomedicine with biomimetic engineering for high‐contrast targeted bioimaging and multiple phototherapies of pancreatic tumors publication-title: Adv. Funct. Mater. – volume: 34 start-page: 5833 year: 2013 end-page: 5842 ident: bib53 article-title: Platinum nanoparticles for the photothermal treatment of Neuro 2A cancer cells publication-title: Biomaterials – volume: 119 year: 2022 ident: bib40 article-title: Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy publication-title: Proc. Natl. Acad. Sci. U.S.A – volume: 397 start-page: 1750 year: 2021 end-page: 1769 ident: bib7 article-title: Breast cancer publication-title: Lancet – volume: 15 start-page: 6362 year: 2024 ident: bib48 article-title: Pt nanoshells with a high NIR-II photothermal conversion efficiency mediates multimodal neuromodulation against ventricular arrhythmias publication-title: Nat. Commun. – volume: 11 year: 2022 ident: bib41 article-title: Amorphous ultra-small Fe-based nanocluster engineered and ICG loaded organo-mesoporous silica for GSH depletion and photothermal-chemodynamic synergistic therapy publication-title: Adv. Healthcare Mater. – volume: 10 start-page: 473 year: 2016 end-page: 482 ident: bib51 article-title: Near-field dielectric scattering promotes optical absorption by platinum nanoparticles publication-title: Nat. Photonics – volume: 2 year: 2022 ident: bib63 article-title: Evaluation of human spermatozoa mitochondrial membrane potential using the JC-1 dye publication-title: Curr. Protoc. – volume: 315 start-page: 1385 year: 2007 end-page: 1388 ident: bib30 article-title: Super plastic bulk metallic glasses at room temperature publication-title: Science – volume: 6 start-page: 765 year: 2007 end-page: 769 ident: bib49 article-title: Synthesis of iron nanometallic glasses and their application in cancer therapy by a localized Fenton reaction publication-title: Nat. Mater. – volume: 304 year: 2023 ident: bib11 article-title: Carbohydrate polymer-based nanocomposites for breast cancer treatment publication-title: Carbohydr. Polym. – volume: 10 year: 2021 ident: bib18 article-title: Recent advances in hypoxia-overcoming strategy of aggregation-induced emission photosensitizers for efficient photodynamic therapy publication-title: Adv. Healthcare Mater. – volume: 40 start-page: 303 year: 2014 end-page: 312 ident: bib23 article-title: Repurposing of gallium-based drugs for antibacterial therapy publication-title: Biofactors – volume: 678 start-page: 42 year: 2025 end-page: 52 ident: bib50 article-title: Pt/Pd dual-modified porphyrin metal-organic frameworks for NIR-II photothermal-enhanced photodynamic/catalytic therapy publication-title: J. Colloid Interface Sci. – volume: 18 start-page: 5556 year: 2024 end-page: 5570 ident: bib20 article-title: Highly-efficient gallium-interference tumor therapy mediated by gallium-enriched prussian blue nanomedicine publication-title: ACS Nano – volume: 2 start-page: 110 year: 2022 end-page: 120 ident: bib35 article-title: Degradation of microplastics by a thermal Fenton reaction publication-title: ACS EST Engg. – volume: 63 year: 2024 ident: bib44 article-title: A light-triggered J-aggregation-regulated therapy conversion: from photodynamic/photothermal therapy to long-lasting chemodynamic therapy for effective tumor ablation publication-title: Angew. Chem. Int. Ed. – volume: 17 start-page: 14406 year: 2023 end-page: 14423 ident: bib25 article-title: Gallium liquid metal: nanotoolbox for antimicrobial applications publication-title: ACS Nano – volume: 16 start-page: 7947 year: 2022 end-page: 7960 ident: bib54 article-title: Nanosized janus AuNR-Pt motor for enhancing NIR-II photoacoustic imaging of deep tumor and Pt publication-title: ACS Nano – volume: 15 start-page: 47725 year: 2023 end-page: 47732 ident: bib57 article-title: Unravelling the surface oxidation-induced evolution of the electronic structure of gallium publication-title: ACS Appl. Mater. Interfaces – volume: 16 start-page: 3105 year: 2022 end-page: 3118 ident: bib52 article-title: Pt decorated T publication-title: ACS Nano – volume: 46 start-page: 2009 year: 1980 end-page: 2013 ident: bib27 article-title: Pharmacokinetics of gallium nitrate in man publication-title: Cancer – volume: 57 start-page: 1174 year: 2024 end-page: 1187 ident: bib37 article-title: Supramolecular coordination complexes for synergistic cancer therapy publication-title: Acc. Chem. Res. – volume: 13 start-page: 342 year: 2013 end-page: 355 ident: bib21 article-title: Iron and cancer: more ore to be mined publication-title: Nat. Rev. Cancer – volume: 365 start-page: 43 year: 2024 end-page: 59 ident: bib10 article-title: Dacarbazine-primed carbon quantum dots coated with breast cancer cell-derived exosomes for improved breast cancer therapy publication-title: J. Contr. Release – volume: 31 year: 2019 ident: bib61 article-title: Plasmonic Pt superstructures with boosted near-infrared absorption and photothermal conversion efficiency in the second biowindow for cancer therapy publication-title: Adv. Mater. – volume: 33 year: 2023 ident: bib19 article-title: Surface-EngineeredVanadium carbide MXenzyme for anti-inflammation and photo enhanced antitumor therapy of colon diseases publication-title: Adv. Funct. Mater. – volume: 46 start-page: 2009 year: 1980 ident: 10.1016/j.mtbio.2025.101869_bib27 article-title: Pharmacokinetics of gallium nitrate in man publication-title: Cancer doi: 10.1002/1097-0142(19801101)46:9<2009::AID-CNCR2820460919>3.0.CO;2-A – volume: 17 start-page: 14406 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib25 article-title: Gallium liquid metal: nanotoolbox for antimicrobial applications publication-title: ACS Nano doi: 10.1021/acsnano.3c06486 – volume: 304 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib11 article-title: Carbohydrate polymer-based nanocomposites for breast cancer treatment publication-title: Carbohydr. Polym. doi: 10.1016/j.carbpol.2022.120510 – volume: 9 start-page: 496 year: 2018 ident: 10.1016/j.mtbio.2025.101869_bib22 article-title: Hypercalcemia of malignancy publication-title: J. Adv. Pract. Oncol. – volume: 63 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib44 article-title: A light-triggered J-aggregation-regulated therapy conversion: from photodynamic/photothermal therapy to long-lasting chemodynamic therapy for effective tumor ablation publication-title: Angew. Chem. Int. Ed. doi: 10.1002/anie.202404395 – volume: 41 start-page: 859 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib4 article-title: Reassessing the benefits and harms of risk-reducing medication considering the persistent risk of breast cancer mortality in estrogen receptor-positive breast cancer publication-title: J. Clin. Oncol. doi: 10.1200/JCO.22.01342 – volume: 13 start-page: 342 year: 2013 ident: 10.1016/j.mtbio.2025.101869_bib21 article-title: Iron and cancer: more ore to be mined publication-title: Nat. Rev. Cancer doi: 10.1038/nrc3495 – volume: 663 start-page: 577 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib45 article-title: Tumor microenvironment sensitization via dual-catalysis of carbon-based nanoenzyme for enhanced photodynamic therapy publication-title: J. Colloid Interface Sci. doi: 10.1016/j.jcis.2024.02.160 – volume: 678 start-page: 42 issue: Part A year: 2025 ident: 10.1016/j.mtbio.2025.101869_bib50 article-title: Pt/Pd dual-modified porphyrin metal-organic frameworks for NIR-II photothermal-enhanced photodynamic/catalytic therapy publication-title: J. Colloid Interface Sci. doi: 10.1016/j.jcis.2024.08.154 – volume: 15 start-page: 6362 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib48 article-title: Pt nanoshells with a high NIR-II photothermal conversion efficiency mediates multimodal neuromodulation against ventricular arrhythmias publication-title: Nat. Commun. doi: 10.1038/s41467-024-50557-w – volume: 11 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib41 article-title: Amorphous ultra-small Fe-based nanocluster engineered and ICG loaded organo-mesoporous silica for GSH depletion and photothermal-chemodynamic synergistic therapy publication-title: Adv. Healthcare Mater. doi: 10.1002/adhm.202201986 – volume: 10 year: 2021 ident: 10.1016/j.mtbio.2025.101869_bib18 article-title: Recent advances in hypoxia-overcoming strategy of aggregation-induced emission photosensitizers for efficient photodynamic therapy publication-title: Adv. Healthcare Mater. doi: 10.1002/adhm.202101607 – year: 2025 ident: 10.1016/j.mtbio.2025.101869_bib17 article-title: Reducing exciton binding energy of antimony-based perovskites by improving the phase purity for efficient solar cells publication-title: Mater. Horiz. doi: 10.1039/D5MH00003C – volume: 559 start-page: 51 year: 2020 ident: 10.1016/j.mtbio.2025.101869_bib59 article-title: Triple stimuli-responsive ZnO quantum dots-conjugated hollow mesoporous carbon nanoplatform for NIR-induced dual model antitumor therapy publication-title: J. Colloid Interface Sci. doi: 10.1016/j.jcis.2019.09.120 – volume: 15 start-page: 657 year: 2025 ident: 10.1016/j.mtbio.2025.101869_bib16 article-title: Microglial APOE4 promotes neuron degeneration in Alzheimer's disease through inhibition of lipid droplet autophagy publication-title: Acta Pharm. Sin. B doi: 10.1016/j.apsb.2024.10.009 – volume: 29 year: 2017 ident: 10.1016/j.mtbio.2025.101869_bib33 article-title: Antiferromagnetic pyrite as the tumor microenvironment-mediated nanoplatform for self-enhanced tumor imaging and therapy publication-title: Adv. Mater. doi: 10.1002/adma.201701683 – volume: 7 year: 2015 ident: 10.1016/j.mtbio.2025.101869_bib55 article-title: One-step synthesis of porous bimetallic PtCu nanocrystals with high electrocatalytic activity for methanol oxidation reaction publication-title: Nanoscale doi: 10.1039/C5NR04557F – volume: 34 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib24 article-title: Visualized gallium/lyticase-integrated antifungal strategy for fungal keratitis treatment publication-title: Adv. Mater. – volume: 6 start-page: 3269 year: 2021 ident: 10.1016/j.mtbio.2025.101869_bib8 article-title: mBioactive nanotherapeutic trends to combat triple negative breast cancer publication-title: Bioact. Mater. – volume: 73 start-page: 17 issue: 2023 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib1 article-title: Cancer statistics publication-title: Ca - Cancer J. Clin. doi: 10.3322/caac.21763 – volume: 15 start-page: 47725 issue: 40 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib57 article-title: Unravelling the surface oxidation-induced evolution of the electronic structure of gallium publication-title: ACS Appl. Mater. Interfaces doi: 10.1021/acsami.3c09324 – volume: 16 start-page: 7947 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib54 article-title: Nanosized janus AuNR-Pt motor for enhancing NIR-II photoacoustic imaging of deep tumor and Pt2+ ion-based chemotherapy publication-title: ACS Nano doi: 10.1021/acsnano.2c00732 – volume: 57 start-page: 1174 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib37 article-title: Supramolecular coordination complexes for synergistic cancer therapy publication-title: Acc. Chem. Res. doi: 10.1021/acs.accounts.4c00031 – volume: 33 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib19 article-title: Surface-EngineeredVanadium carbide MXenzyme for anti-inflammation and photo enhanced antitumor therapy of colon diseases publication-title: Adv. Funct. Mater. doi: 10.1002/adfm.202211846 – volume: 27 start-page: i30 year: 2016 ident: 10.1016/j.mtbio.2025.101869_bib6 article-title: Neoadjuvant chemotherapy in ovarian cancer revisited publication-title: Ann. Oncol. doi: 10.1093/annonc/mdw092 – volume: 10 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib9 article-title: Single atom-doped nanosonosensitizers for mutually optimized sono/chemo-nanodynamic therapy of triple negative breast cancer publication-title: Adv. Sci. – volume: 2 start-page: 110 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib35 article-title: Degradation of microplastics by a thermal Fenton reaction publication-title: ACS EST Engg. doi: 10.1021/acsestengg.1c00323 – volume: 506 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib39 article-title: Near-infrared boron–dipyrrin (BODIPY) nanomaterials: molecular design and anti-tumor therapeutics publication-title: Coord. Chem. Rev. doi: 10.1016/j.ccr.2024.215718 – volume: 44 start-page: 1722 year: 1979 ident: 10.1016/j.mtbio.2025.101869_bib28 article-title: Clinical toxicologic and pharmacologic studies of gallium nitrate publication-title: Cancer doi: 10.1002/1097-0142(197911)44:5<1722::AID-CNCR2820440528>3.0.CO;2-C – volume: 18 start-page: 5556 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib20 article-title: Highly-efficient gallium-interference tumor therapy mediated by gallium-enriched prussian blue nanomedicine publication-title: ACS Nano – volume: 34 start-page: 5833 year: 2013 ident: 10.1016/j.mtbio.2025.101869_bib53 article-title: Platinum nanoparticles for the photothermal treatment of Neuro 2A cancer cells publication-title: Biomaterials doi: 10.1016/j.biomaterials.2013.03.077 – volume: 2789 start-page: 153 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib62 article-title: Detection of nanoparticle-mediated change in mitochondrial membrane potential in T cells using JC-1 dye publication-title: Methods Mol. Biol. doi: 10.1007/978-1-0716-3786-9_16 – volume: 10 start-page: 473 year: 2016 ident: 10.1016/j.mtbio.2025.101869_bib51 article-title: Near-field dielectric scattering promotes optical absorption by platinum nanoparticles publication-title: Nat. Photonics doi: 10.1038/nphoton.2016.76 – volume: 13 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib43 article-title: Biodegradable cascade-amplified nanotheranostics for photoacoustic-guided synergistic PTT/CDT/starvation antitumor in the NIR-II window publication-title: Adv. Healthcare Mater. – volume: 683 start-page: 910 year: 2025 ident: 10.1016/j.mtbio.2025.101869_bib46 article-title: Oxidative stress-augmented Cu-doped hollow mesoporous carbon nanozyme for photothermal/photodynamic synergistic therapy publication-title: J. Colloid Interface Sci. doi: 10.1016/j.jcis.2024.12.076 – volume: 34 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib14 article-title: Construction of through‐space charge‐transfer nanoparticles for facilely realizing high‐performance NIR‐II cancer phototheranostics publication-title: Adv. Funct. Mater. doi: 10.1002/adfm.202407317 – volume: 13 start-page: 2544 year: 2019 ident: 10.1016/j.mtbio.2025.101869_bib34 article-title: Low power single laser activated synergistic cancer phototherapy using photosensitizer functionalized dual plasmonic photothermal nanoagents publication-title: ACS Nano – volume: 6 start-page: 3812 year: 2021 ident: 10.1016/j.mtbio.2025.101869_bib29 article-title: Ultrasmall Ga-ICG nanoparticles based gallium ion/photodynamic synergistic therapy to eradicate biofilms and against drug-resistant bacterial liver abscess publication-title: Bioact. Mater. – volume: 32 start-page: 860 year: 2021 ident: 10.1016/j.mtbio.2025.101869_bib56 article-title: Room-temperature synthesis of γ-Ga2O3 nanoparticles from galliummetal via ultrasound irradiation publication-title: Adv. Powder Technol. doi: 10.1016/j.apt.2021.01.032 – volume: 31 year: 2019 ident: 10.1016/j.mtbio.2025.101869_bib61 article-title: Plasmonic Pt superstructures with boosted near-infrared absorption and photothermal conversion efficiency in the second biowindow for cancer therapy publication-title: Adv. Mater. doi: 10.1002/adma.201904836 – volume: 315 start-page: 1385 year: 2007 ident: 10.1016/j.mtbio.2025.101869_bib30 article-title: Super plastic bulk metallic glasses at room temperature publication-title: Science doi: 10.1126/science.1136726 – volume: 51 start-page: 685 year: 2025 ident: 10.1016/j.mtbio.2025.101869_bib2 article-title: Pt loaded CoFe2O4-based nanoparticles for breast cancer treatment with chemodynamic therapy and sonodynamic therapy publication-title: Cerm. Int. doi: 10.1016/j.ceramint.2024.11.050 – volume: 518 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib38 article-title: Biomarker-activatable photosensitizers with aggregation-induced emission characteristics for photodynamic therapy publication-title: Coord. Chem. Rev. doi: 10.1016/j.ccr.2024.216056 – volume: 382 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib5 article-title: Advances in the care of breast cancer survivors publication-title: BMJ Br. Med. J. (Clin. Res. Ed.) – volume: 25 start-page: 89 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib26 article-title: CTNI-57. Preliminary results of a phase 1 trial of oral gallium maltolate in recurrent glioblastoma publication-title: Neuro Oncol. doi: 10.1093/neuonc/noad179.0339 – start-page: 796 year: 2025 ident: 10.1016/j.mtbio.2025.101869_bib42 article-title: Photothermal and enhanced chemodynamic reinforced anti-tumor therapy based on PDA@POM nanocomposites publication-title: J. Colloid Interface Sci. 678 Part C doi: 10.1016/j.jcis.2024.09.160 – volume: 365 start-page: 43 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib10 article-title: Dacarbazine-primed carbon quantum dots coated with breast cancer cell-derived exosomes for improved breast cancer therapy publication-title: J. Contr. Release doi: 10.1016/j.jconrel.2023.11.005 – volume: 481 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib47 article-title: Nanozyme-mediated biocatalysis as a mitochondrial oxidative stress amplifier for tumor nanocatalytic immunotherapy publication-title: Chem. Eng. J. doi: 10.1016/j.cej.2023.148270 – volume: 2 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib63 article-title: Evaluation of human spermatozoa mitochondrial membrane potential using the JC-1 dye publication-title: Curr. Protoc. doi: 10.1002/cpz1.531 – volume: 14 start-page: 36527 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib15 article-title: In situ engineering of the Cu+/Cu0 interface to boost C2+ selectivity in CO2 electroreduction publication-title: ACS Appl. Mater. Interfaces doi: 10.1021/acsami.2c05992 – volume: 16 start-page: 3105 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib52 article-title: Pt decorated Ti3C2Tx MXene with NIR-II light amplified nanozyme catalytic activity for efficient phototheranostics publication-title: ACS Nano doi: 10.1021/acsnano.1c10732 – volume: 34 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib13 article-title: A NIR‐II‐emissive organic nanomedicine with biomimetic engineering for high‐contrast targeted bioimaging and multiple phototherapies of pancreatic tumors publication-title: Adv. Funct. Mater. – volume: 10 start-page: 123 year: 2011 ident: 10.1016/j.mtbio.2025.101869_bib31 article-title: A damage-tolerant glass publication-title: Nat. Mater. doi: 10.1038/nmat2930 – volume: 639 start-page: 249 year: 2023 ident: 10.1016/j.mtbio.2025.101869_bib60 article-title: Degradable iron-rich mesoporous dopamine as a dual-glutathione depletion nanoplatform for photothermal-enhanced ferroptosis and chemodynamic therapy publication-title: J. Colloid Interface Sci. doi: 10.1016/j.jcis.2023.02.041 – volume: 55 start-page: 2101 year: 2016 ident: 10.1016/j.mtbio.2025.101869_bib32 article-title: Synthesis of iron nanometallic glasses and their application in cancer therapy by a localized Fenton reaction publication-title: Angew. Chem. Int. Ed. doi: 10.1002/anie.201510031 – volume: 119 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib40 article-title: Phenylthiol-BODIPY-based supramolecular metallacycles for synergistic tumor chemo-photodynamic therapy publication-title: Proc. Natl. Acad. Sci. U.S.A doi: 10.1073/pnas.2203994119 – volume: 53 start-page: 3167 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib36 article-title: Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications publication-title: Chem. Soc. Rev. doi: 10.1039/D3CS00926B – volume: 153 year: 2020 ident: 10.1016/j.mtbio.2025.101869_bib58 article-title: Oxidation induced restructuring of Rh-Ga SCALMS model catalyst systems publication-title: J. Chem. Phys. doi: 10.1063/5.0021647 – volume: 397 start-page: 1750 year: 2021 ident: 10.1016/j.mtbio.2025.101869_bib7 article-title: Breast cancer publication-title: Lancet doi: 10.1016/S0140-6736(20)32381-3 – volume: 6 start-page: 765 year: 2007 ident: 10.1016/j.mtbio.2025.101869_bib49 article-title: Synthesis of iron nanometallic glasses and their application in cancer therapy by a localized Fenton reaction publication-title: Nat. Mater. doi: 10.1038/nmat1983 – volume: 40 start-page: 303 year: 2014 ident: 10.1016/j.mtbio.2025.101869_bib23 article-title: Repurposing of gallium-based drugs for antibacterial therapy publication-title: Biofactors doi: 10.1002/biof.1159 – volume: 329 year: 2024 ident: 10.1016/j.mtbio.2025.101869_bib12 article-title: A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy publication-title: Carbohydr. Polym. doi: 10.1016/j.carbpol.2024.121795 – volume: 42 start-page: 913 year: 2022 ident: 10.1016/j.mtbio.2025.101869_bib3 article-title: Breast cancer: an up-to-date review and future perspectives publication-title: Cancer Commun. doi: 10.1002/cac2.12358 |
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| Title | Highly efficient NIR-II photothermal therapy amplified ROS oxide breast tumor therapy by mesoporous gallium-enriched platinum nanomedicine |
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