The Effectiveness of a Weak Opioid Medication versus a Cyclo-Oxygenase-2 (COX-2) Selective Non-Steroidal Anti-Inflammatory Drug in Treating Flare-Up of Chronic Low-Back Pain: Results from Two Randomized, Double-Blind, 6-Week Studies - O'Donnell, JB; Ekman, EF; Spalding, WM; Bhadra, P; McCabe, D; Berger, MF (Journal of international medical research, 2009)
Keywords: Adolescent; Adult; Aged; Analgesics, Opioid - adverse effects; Analgesics, Opioid - therapeutic use; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Causality; Celecoxib; Chronic Disease; Cyclooxygenase 2 Inhibitors - adverse effects; Cyclooxygenase 2 Inhibitors - therapeutic use; Demography; Double-Blind Method; Female; Humans; Low Back Pain - drug therapy; Male; Middle Aged; Pyrazoles - adverse effects; Pyrazoles - therapeutic use; Sulfonamides - adverse effects; Sulfonamides - therapeutic use; Tramadol - adverse effects; Tramadol - therapeutic use; Treatment Outcome; Young Adult; Chronic low-back pain; Cyclo-oxygenase-2 (COX-2); Celecoxib; Tramadol; Opioids; Non-steroidal anti-inflammatory drugs