The Molecular and Mechanistic Insights Based on Gut–Liver Axis: Nutritional Target for Non-Alcoholic Fatty Liver Disease (NAFLD) Improvement

• Published in: International journal of molecular sciences Vol. 21; no. 9; p. 3066
• Main Authors: Ji, Yun, Yin, Yue, Sun, Lijun, Zhang, Weizhen
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.04.2020; MDPI
• Subjects: Animals; Bacteria; Bacteria - classification; Bacteria - metabolism; Bile; Deoxyribonucleic acid; Diet; Dietary Fiber - pharmacology; Dietary Fiber - therapeutic use; Disease Progression; DNA; DNA methylation; Dysbiosis - complications; Dysbiosis - diet therapy; Epigenetics; Fatty liver; Gastrointestinal Microbiome - drug effects; Gene expression; Homeostasis; Humans; Inflammation; Insulin resistance; Liver diseases; Metabolism; Metabolites; Microbiota; Non-alcoholic Fatty Liver Disease - microbiology; Non-alcoholic Fatty Liver Disease - pathology; Non-alcoholic Fatty Liver Disease - prevention & control; Obesity; Pathogenesis; Permeability; Polyunsaturated fatty acids; Probiotics - pharmacology; Probiotics - therapeutic use; Review; nutrition; liver disease; gut–liver axis; barrier function; gut microbiota

Non-alcoholic fatty liver disease (NAFLD) is recognized as the most frequent classification of liver disease around the globe. Along with the sequencing technologies, gut microbiota has been regarded as a vital factor for the maintenance of human and animal health and the mediation of multiple disea...